Capecitabine, sold under the brand name Xeloda among others, is a anticancer medication used to treat breast cancer, gastric cancer and colorectal cancer...
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months vs. 25.1 months) compared to the combination of lapatinib and capecitabine. Based on that trial, the U.S. Food and Drug Administration (FDA) approved...
29 KB (2,696 words) - 14:16, 27 July 2024
is a kinase inhibitor indicated in combination with trastuzumab and capecitabine for the treatment of adults with advanced unresectable or metastatic...
21 KB (1,685 words) - 05:17, 16 July 2024
CAPOX (also called XELOX) is a chemotherapy regimen consisting of capecitabine (trade name Xeloda) combined with oxaliplatin. Xelox regime operates in...
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cabozantinib, cytarabine, doxorubicin, and fluorouracil and its prodrug capecitabine. Targeted cancer therapies, especially the tyrosine kinase inhibitors...
16 KB (1,639 words) - 14:02, 28 August 2024
lapatinib in combination therapy for breast cancer patients already using capecitabine (Xeloda). In January 2010, Tykerb received accelerated approval for the...
17 KB (1,479 words) - 09:07, 5 September 2024
Erlotinib Gefitinib Imatinib Vemurafenib Vismodegib Azacitidine Azathioprine Capecitabine Cladribine Clofarabine Cytarabine Decitabine Doxifluridine Fludarabine...
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following an overdose of chemotherapy drugs 5-fluorouracil (5-FU) or capecitabine regardless of the presence of symptoms, or who exhibit early-onset, severe...
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com. Walsh, Sandy. "Press Announcements - FDA approves first generic capecitabine to treat colorectal and breast cancers". www.fda.gov. United States Food...
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treatment of cancer. Beside 5-FU, widely prescribed oral fluoropyrimidine capecitabine (Xeloda) could put DPD-deficient patients at risk of experiencing severe...
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5-fluorouracil, leucovorin, and irinotecan. The regimen XELIRI consists of capecitabine and irinotecan. It may also be used together with fluorouracil and folinic...
26 KB (2,315 words) - 04:55, 13 April 2024
antimetabolites and are used as anticancer medications, which include: Capecitabine Carmofur (HCFU) Doxifluridine Fluorouracil (5-FU) Tegafur Some metabolites...
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ribonucleotide formyltransferase. The fluoropyrimidines include fluorouracil and capecitabine. Fluorouracil is a nucleobase analogue that is metabolised in cells to...
155 KB (17,546 words) - 16:49, 16 August 2024
184 randomly received physician's choice of chemotherapy (eribulin, capecitabine, gemcitabine, nab paclitaxel, or paclitaxel). The results showed improvement...
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drugs approved by the Food and Drug Administration in the United States. Capecitabine tablets, a nucleoside metabolic inhibitor for the treatment of colon...
20 KB (1,693 words) - 16:58, 26 September 2024
treatment with docetaxel. Docetaxel is also used in combination with capecitabine, a DNA synthesis inhibitor. Docetaxel is a cytotoxic chemotherapeutic...
45 KB (4,765 words) - 15:32, 26 September 2024
anthracyclines (doxorubicin and epirubicin), antimetabolites (fluorouracil, capecitabine, and methotrexate), taxanes (docetaxel and paclitaxel), and platinum-based...
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kill tumours. Some people seem to respond to a combination chemo called capecitabine and temozolomide but there is no report that it totally cured people...
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include capecitabine, fluorouracil, irinotecan, oxaliplatin and UFT. The drugs capecitabine and fluorouracil are interchangeable, with capecitabine being...
145 KB (15,860 words) - 13:57, 30 September 2024
(leucovorin) and fluorouracil in a combination known as FOLFOX or along with capecitabine in a combination known as CAPOX or XELOX. It may also be effective against...
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used, such as doxorubicin with streptozocin and fluorouracil (5-FU) and capecitabine with temozolomide.[citation needed] Although marginally effective in...
28 KB (2,476 words) - 01:37, 1 October 2024
gemcitabine as a single agent, or gemcitabine plus cisplatin, irinotecan, or capecitabine. A small pilot study suggested possible benefit from the tyrosine kinase...
74 KB (7,649 words) - 05:26, 16 August 2024
(Mercaptopurine# Tioguanine#) Pyrimidine Thymidylate synthase inhibitor (Capecitabine# Carmofur Doxifluridine Floxuridine Fluorouracil# Tegafur (+gimeracil/oteracil))...
31 KB (2,908 words) - 06:38, 22 September 2024
(Mercaptopurine# Tioguanine#) Pyrimidine Thymidylate synthase inhibitor (Capecitabine# Carmofur Doxifluridine Floxuridine Fluorouracil# Tegafur (+gimeracil/oteracil))...
18 KB (1,467 words) - 23:44, 20 August 2024
(Mercaptopurine# Tioguanine#) Pyrimidine Thymidylate synthase inhibitor (Capecitabine# Carmofur Doxifluridine Floxuridine Fluorouracil# Tegafur (+gimeracil/oteracil))...
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orally (e.g. specialty drugs, melphalan (trade name Alkeran), busulfan, capecitabine). University of Pittsburgh Medical Center National Cancer Institute in...
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5-fluorouracil, cisplatin, epirubicin, etoposide, docetaxel, oxaliplatin, capecitabine, or irinotecan. The TNM staging system is also used. In a study of open-access...
79 KB (8,199 words) - 08:50, 12 August 2024
limited to the following: 5-Fluorouracil (5-FU) 6-Mercaptopurine (6-MP) Capecitabine (Xeloda®) Cytarabine (Ara-C®) Floxuridine Fludarabine Gemcitabine (Gemzar®)...
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of fluoropyrimidines, a class of drugs that includes 5-fluorouracil, capecitabine, and tegafur. Genetic variations within the DPD gene (DPYD) can lead...
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symptoms as well, such as thin, brittle hair. The anti-cancer medication capecitabine may cause the loss of fingerprints. Swelling of the fingers, such as...
111 KB (12,052 words) - 00:43, 19 September 2024