Cholesterol 7 alpha-hydroxylase also known as cholesterol 7-alpha-monooxygenase or cytochrome P450 7A1 (CYP7A1) is an enzyme that in humans is encoded...
22 KB (2,658 words) - 06:17, 17 August 2024
respectively. Cholic acid downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis), and cholesterol does the opposite. This is why...
10 KB (785 words) - 12:04, 13 May 2024
Hydroxylation (redirect from Hydroxylase)
into dopamine. 17α-Hydroxylase Cholesterol 7 alpha-hydroxylase Dopamine β-hydroxylase Phenylalanine hydroxylase Tyrosine hydroxylase One example of non-biological...
9 KB (1,058 words) - 07:42, 20 June 2024
phloroglucinol. In an animal model, THAP was reported to enhance cholesterol 7 alpha-hydroxylase (CYP7A1) activity. THAP is also used as a matrix in matrix-assisted...
3 KB (168 words) - 02:11, 1 July 2022
down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase expression, therefore making it easier for cholesterol to precipitate and...
10 KB (1,091 words) - 01:14, 8 October 2024
similar to human prostacyclin synthase (CYP8) and 31% similar to cholesterol 7 alpha-hydroxylase (CYP7). This enzymatic activity is now known to be performed...
4 KB (418 words) - 12:48, 26 August 2023
nucleus by the enzyme cholesterol 7 alpha-hydroxylase. This enzyme is down-regulated by cholic acid, up-regulated by cholesterol and is inhibited by the...
36 KB (4,583 words) - 04:41, 8 October 2024
Boyd GS (1971). "The oxidation of cholesterol in rat liver sub-cellular particles The cholesterol-7-alpha-Hydroxylase enzyme system". Eur. J. Biochem....
3 KB (252 words) - 06:19, 3 December 2023
27-triol + NADP+ + H2O 25-hydroxycholesterol 7α-hydroxylase is a heme-thiolate protein (P-450). cholesterol; 25-hydroxycholesterol. Toll A, Wikvall K, Sudjana-Sugiaman...
3 KB (274 words) - 14:14, 27 November 2023
D 1-alpha-hydroxylase (VD 1A hydroxylase) also known as calcidiol 1-monooxygenase or cytochrome p450 27B1 (CYP27B1) or simply 1-alpha-hydroxylase is a...
13 KB (1,499 words) - 16:32, 11 August 2024
Steroid 21-hydroxylase is a protein that in humans is encoded by the CYP21A2 gene. The protein is an enzyme that hydroxylates steroids at the C21 position...
50 KB (5,615 words) - 20:02, 8 August 2024
3-Ketosteroid 9alpha-monooxygenase (redirect from 3-ketosteroid 9alpha-hydroxylase)
(April 2009). "Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis"...
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is the suppression of cholesterol 7 alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis from cholesterol. FXR does not directly...
17 KB (1,945 words) - 06:08, 25 July 2024
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) is a genetic disorder characterized by impaired production of cortisol in the adrenal...
177 KB (20,588 words) - 05:38, 2 November 2024
the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP". Genes & Development. 7 (10): 1871–84. doi:10.1101/gad.7.10.1871...
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hydroxylases, also termed cytochrome P450 ω-hydroxylases, CYP450 omega hydroxylases, CYP450 ω-hydroxylases, CYP omega hydroxylase, CYP ω-hydroxylases...
14 KB (1,685 words) - 02:13, 17 June 2024
7α-Hydroxy-4-cholesten-3-one (redirect from 7 alpha-hydroxy-4-cholesten-3-one)
bile acids from cholesterol. Its precursor, 7α-hydroxycholesterol, is produced from cholesterol by hepatic cholesterol 7α-hydroxylase (CYP7A1). It is...
4 KB (365 words) - 22:44, 17 December 2023
receptor alpha with liver X receptor alpha antagonizes the stimulatory effect of their respective ligands on the murine cholesterol 7alpha-hydroxylase gene...
14 KB (1,641 words) - 03:02, 20 June 2024
inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase". Arch. Biochem. Biophys. 311 (2):...
6 KB (476 words) - 17:17, 29 September 2024
receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene". Mol. Endocrinol. 18 (10): 2424–39. doi:10.1210/me.2004-0009...
11 KB (1,103 words) - 22:24, 27 March 2024
(ACTH). The cells of the zona glomerulosa do not express 11β-hydroxylase and 17α-hydroxylase. This is the reason zona glomerulosa cannot synthesize cortisol...
13 KB (1,476 words) - 20:50, 17 July 2024
P450, family 8, subfamily B, polypeptide 1) also known as sterol 12-alpha-hydroxylase is a protein which in humans is encoded by the CYP8B1 gene. This gene...
6 KB (827 words) - 05:01, 15 December 2023
Late onset congenital adrenal hyperplasia (category Cholesterol and steroid metabolism disorders)
Noaimi AA, Saleh BO, Anbar ZN (December 2009). "The frequency of 21-alpha hydroxylase enzyme deficiency and related sex hormones in Iraqi healthy male subjects...
43 KB (4,673 words) - 09:43, 2 November 2024
25-hydroxycholesterol 7-alpha-hydroxylase also known as oxysterol and steroid 7-alpha-hydroxylase is an enzyme that in humans is encoded by the CYP7B1...
9 KB (1,147 words) - 04:52, 15 December 2023
CYP2R1 (redirect from Cholecalciferol 25-hydroxylase)
cholesterol, steroids and other lipids. CYP2R1 is present in the endoplasmic reticulum of the liver (the microsomal fraction). It has 25-hydroxylase activity...
9 KB (1,133 words) - 14:06, 24 January 2024
Cholecalciferol (redirect from Activated 7-dehydrocholesterol)
ingested. Hydroxylation in the kidneys of calcifediol to calcitriol by 1-alpha-hydroxylase is tightly regulated: it is stimulated by parathyroid hormone and...
41 KB (4,177 words) - 06:59, 25 October 2024
17α-Hydroxyprogesterone (redirect from 17-alpha-hydroxyprogesterone)
PMC 3509141. PMID 23209664. Kim SM, Rhee JH (2015). "A case of 17 alpha-hydroxylase deficiency". Clinical and Experimental Reproductive Medicine. 42 (2)...
14 KB (1,126 words) - 10:08, 7 July 2024
7α-Hydroxycholesterol (redirect from 7-alpha-hydroxycholesterol)
7α-Hydroxycholesterol is a precursor of bile acids, created by cholesterol 7α-hydroxylase (CYP7A1). Its formation is the rate-determining step in bile acid...
3 KB (69 words) - 22:52, 27 April 2023
genes coding for steroidogenic enzymes, especially P450scc, steroid 11β-hydroxylase, and their associated electron transfer proteins. This effect is observed...
18 KB (1,830 words) - 01:25, 26 September 2024
5-pyridoxate dioxygenase - 6-endo-hydroxycineole dehydrogenase - 7-deoxyloganin 7-hydroxylase - 7beta-hydroxysteroid dehydrogenase (NADP+) - 8-oxocoformycin...
23 KB (1,969 words) - 13:07, 28 September 2024