Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard's lab had suggested...

The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family....

and locomotor activity, mediating some behaviors and modulating dopamine receptor D2-mediated events. They play a role in addiction by facilitating the...

to. The D1-like class of dopamine receptors is coupled to Gαs/olf and stimulates adenylate cyclase production, whereas the D2-like class is coupled to...

A dopamine agonist is a compound that activates dopamine receptors. There are two families of dopamine receptors, D1-like and D2-like. They are all G protein-coupled...

The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of DRD4...

Dopamine receptor D3 is a protein that in humans is encoded by the DRD3 gene. This gene encodes the D3 subtype of the dopamine receptor. The D3 subtype...

antipsychotics. Dopamine supersensitivity may be caused by the dopamine receptor D2 antagonizing effect of antipsychotics, causing a compensatory increase in D2 receptors...

Dopamine receptor D5, also known as D1BR, is a protein that in humans is encoded by the DRD5 gene. It belongs to the D1-like receptor family along with...

The D1–D2 dopamine receptor heteromer is a receptor heteromer consisting of D1 and D2 protomers. D1 and D2 receptors interact primarily through discrete...

the dopamine receptor (D2). Aripiprazole is a partial agonist at dopamine D2 receptors, partial agonist at 5-HT1A receptors and at 5-HT2A, receptors. It...

of the dopamine receptor D2 plays a role in self-administration and the reinforcing effects of cocaine and other stimulants. The D2 receptor availability...

anterior pituitary gland lactotrophs by binding to dopamine receptor D2. Some antipsychotic drugs block dopamine in the tuberoinfundibular pathway, which can...

The D2-like receptors are a subfamily of dopamine receptors that bind the endogenous neurotransmitter dopamine. The D2-like subfamily consists of three...

on decreased levels of dopamine activity due to: Dopamine receptor blockade Genetically reduced function of dopamine receptor D2 Sympathoadrenal hyperactivity...

area contains a large population of type D2 dopamine receptors. Consequently, drugs that activate D2 receptors have a high potential to cause nausea. This...

and DRD5) or D2-type (i.e., DRD2, DRD3, and DRD4) dopamine receptors. A subpopulation of MSNs contain both D1-type and D2-type receptors, with approximately 40%...

(300 μg/kg), the D2/D3 receptors were 94% occupied, while at the lowest dose (1 μg/kg), receptors were 5% occupied. Dopamine D2 and D3 receptor occupancy in...

behavioural supersensitivity to dopamine and a marked rise in the number of dopamine D2 receptors in the high-affinity state for dopamine. This latter work implies...

taken by mouth. Cabergoline is an ergot derivative and a potent dopamine D2 receptor agonist. Cabergoline was patented in 1980 and approved for medical...

System Dopamine receptor D2, a protein Levuglandin D2 Prostaglandin D2 receptor, a G-protein coupled receptor Resolvin D2 Cyclin D2 (CCND2) Vitamin D2, or...

A2A receptor has been shown to interact with Dopamine receptor D2. As a result, Adenosine receptor A2A decreases activity in the Dopamine D2 receptors. The...

stimulating beta-2 adrenergic receptors and peripheral dopamine receptor D1 and dopamine receptor D2. It also inhibits the neuronal re-uptake of norepinephrine...

evidence indicates abnormal dopamine receptor D2 structure, as well as a reduced link between dopamine receptor D1 and receptor D2. Studies have shown that...

disorders. Dopamine is now one of the primary neurotransmitters implicated in psychotic symptomology. Blocking dopamine receptors (namely, the dopamine D2 receptors)...

respective main articles of the individual subtypes: D2-like receptor "Dopamine D1-Like Receptor Family Signaling Pathways". Rndsystems. 26 March 2022...

D2 receptor of 60%+, brexpiprazole has an intrinsic activity at the same receptor of about 45%. For aripiprazole, this means more dopamine receptor activation...

2015). "Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors". British Journal of Pharmacology. 172 (4):...

interval timing, whereas antagonists of D2 type dopamine receptors typically slow timing;... Depletion of dopamine in healthy volunteers impairs timing,...

agonist of the dopamine D2 receptor. It also interacts with other dopamine receptors and with various serotonin and adrenergic receptors. Bromocriptine...