HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene. It is an empty intracellular molecule...
36 KB (4,439 words) - 06:11, 25 December 2023
Human leukocyte antigen (redirect from HLA antigen)
and three minor MHC class I genes in HLA. Major MHC class I HLA-A HLA-B HLA-C Minor genes are HLA-E, HLA-F and HLA-G. β2-microglobulin binds with major...
51 KB (5,942 words) - 15:58, 25 September 2024
polymorphic HLA-A (HLA-A) HLA-B (HLA-B) HLA-C (HLA-C) Less polymorphic HLA-E (HLA-E) HLA-F (HLA-F) HLA-G (HLA-G) HLA-K (pseudogene) HLA-L (pseudogene)...
21 KB (2,610 words) - 08:24, 9 August 2024
HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR (Human...
31 KB (2,293 words) - 12:25, 28 December 2023
HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles...
26 KB (2,119 words) - 03:34, 29 November 2023
HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility...
27 KB (3,411 words) - 01:57, 10 March 2024
HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07:01-B*08:01) is a multigene...
23 KB (2,540 words) - 15:48, 3 July 2024
HLA-DQ2 (DQ2) is a serotype group within HLA-DQ (DQ) serotyping system. The serotype is determined by the antibody recognition of β2 subset of DQ β-chains...
33 KB (3,380 words) - 17:14, 6 July 2024
HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products. B35 is one of the largest B serotype groups, it currently...
6 KB (149 words) - 14:44, 26 June 2024
HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene. DRB1 encodes the most prevalent beta...
6 KB (677 words) - 21:44, 22 October 2024
of the HLA System revised the nomenclature for HLAs. Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is...
31 KB (1,695 words) - 14:33, 26 June 2024
HLA-B51 (B51) is an HLA-B serotype. The serotype identifies the more common HLA-B*51 gene products. B51 is a split antigen of the broad antigen B5, and...
16 KB (960 words) - 01:10, 1 June 2024
HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 broad antigen. DQ8 is determined...
67 KB (5,460 words) - 15:43, 3 July 2024
critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system...
17 KB (1,889 words) - 01:57, 10 March 2024
HLA-DR15 (DR15) is a HLA-DR serotype that recognizes the DRB1*1501 to *1505 and *1507 gene products. DR15 is found at high levels from Ireland to Central...
16 KB (1,100 words) - 13:55, 26 March 2024
cells to avoid immune system is upregulation of non-classical MHC I (HLA-E, HLA-F, HLA-G) which prevents NK-mediated immune reaction by interaction with...
11 KB (1,356 words) - 23:48, 15 December 2021
The DQ loci are in close genetic linkage to HLA-DR, and less closely linked to HLA-DP, HLA-A, HLA-B and HLA-C. Different isoforms of DQ can bind to and...
36 KB (2,596 words) - 22:31, 6 November 2024
HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E...
7 KB (954 words) - 16:08, 1 April 2024
complex (MHC) class II membrane-bound proteins. HLA-DM is encoded by the genes HLA-DMA and HLA-DMB. HLA-DM is a molecular chaperone that works in lysosomes...
19 KB (2,371 words) - 10:20, 27 October 2024
HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split 'antigens' serotypes. DR3 is a component gene-allele of the AH8.1 haplotype in Northern and Western...
9 KB (697 words) - 02:42, 27 January 2024
Major histocompatibility complex (section HLA biology)
most studied HLA genes are the nine classical MHC genes: HLA-A, HLA-B, HLA-C, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, and HLA-DRB1. In humans...
58 KB (6,785 words) - 20:25, 21 September 2024
HLA-B52 (B52) is an HLA-B serotype. The serotype identifies the more common HLA-B*52 gene products. B52 is a split antigen of the broad antigen B5, and...
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HLA-DRB3 is linked to these HLA-DR serotypes and DRB1 allele groups: HLA-DR3 - DRB1*03 HLA-DR5 - HLA-DR11 - DRB1*11 HLA-DR12 - DRB1*12 HLA-DR6 - HLA-DR13...
11 KB (884 words) - 02:43, 27 January 2024
affected in the UK have a specific human leukocyte antigen known as the HLA-B27 antigen. The underlying mechanism is believed to be autoimmune or autoinflammatory...
56 KB (5,992 words) - 03:13, 19 October 2024
HLA DR3-DQ2 is a double serotype that specifically recognizes cells from individuals who carry a multigene HLA DR, DQ haplotype. Certain HLA DR and DQ...
51 KB (5,010 words) - 20:40, 4 July 2024
HLA-G histocompatibility antigen, class I, G, also known as human leukocyte antigen G (HLA-G), is a protein that in humans is encoded by the HLA-G gene...
21 KB (2,629 words) - 04:05, 26 August 2024
SH, O'Callaghan CA (Dec 2000). "Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors". European Journal of Immunology...
9 KB (1,162 words) - 19:39, 3 April 2024
HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene. Also known as HLA-DXA or DAAP-381D23...
10 KB (1,251 words) - 06:48, 11 July 2024
HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1; later, it was...
19 KB (1,482 words) - 03:28, 19 October 2022
HLA-DR11 (DR11) is a HLA-DR serotype that recognizes the DRB1*1101 to *1110. DR11 serotype is a split antigen of the older HLA-DR5 serotype group which...
12 KB (829 words) - 19:54, 12 August 2023