• Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,635 words) - 06:03, 24 August 2024
  • Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
    59 KB (6,727 words) - 06:01, 27 October 2024
  • Thumbnail for Epidermal growth factor receptor
    epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 14:26, 16 July 2024
  • Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
    8 KB (827 words) - 22:08, 3 December 2023
  • A growth factor receptor is a receptor that binds to a growth factor. Growth factor receptors are the first stop in cells where the signaling cascade...
    5 KB (591 words) - 15:41, 29 April 2024
  • Thumbnail for Fibroblast growth factor receptor 2
    Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
    14 KB (1,745 words) - 09:02, 15 July 2024
  • Thumbnail for Insulin-like growth factor 1
    is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
    35 KB (4,575 words) - 09:00, 2 November 2024
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    27 KB (3,064 words) - 04:17, 25 November 2024
  • Thumbnail for Hepatocyte nuclear factor 4 alpha
    Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is...
    18 KB (2,230 words) - 15:35, 22 August 2024
  • Thumbnail for Crizotinib
    Crizotinib (category Receptor tyrosine kinase inhibitors)
    cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the oncogenesis...
    22 KB (1,866 words) - 05:42, 2 November 2024
  • Thumbnail for Platelet-derived growth factor receptor
    Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • Thumbnail for Fibroblast growth factor receptor 1
    Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
    44 KB (5,003 words) - 07:11, 15 October 2024
  • Thumbnail for Insulin-like growth factor
    The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
    14 KB (1,689 words) - 01:31, 19 August 2024
  • through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular...
    6 KB (596 words) - 05:15, 1 January 2024
  • Thumbnail for Platelet-derived growth factor receptor A
    Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
    29 KB (3,354 words) - 17:01, 9 December 2023
  • Thumbnail for Fibroblast growth factor receptor 3
    Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
    17 KB (1,845 words) - 01:41, 9 October 2024
  • Thumbnail for Insulin-like growth factor 2 receptor
    Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
    13 KB (1,664 words) - 16:27, 25 May 2024
  • Growth factor receptor inhibitors (growth factor inhibitors, growth factor receptor blockers, growth factor blockers, growth factor receptor antagonists...
    4 KB (381 words) - 22:35, 2 December 2023
  • Thumbnail for Low-affinity nerve growth factor receptor
    nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3...
    37 KB (4,235 words) - 21:48, 19 November 2024
  • Thumbnail for Insulin-like growth factor 1 receptor
    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
    29 KB (3,603 words) - 16:26, 25 May 2024
  • Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
    40 KB (4,578 words) - 12:30, 10 September 2024
  • Thumbnail for TNF receptor superfamily
    exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. In their active form, the majority of TNF receptors form trimeric...
    8 KB (501 words) - 13:55, 10 September 2024
  • Thumbnail for MST1
    Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded...
    7 KB (901 words) - 22:17, 3 March 2023
  • fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor. Members...
    25 KB (3,124 words) - 21:38, 18 August 2024
  • Thumbnail for Insulin-like growth factor 2
    Insulin-like growth factor 2 has been shown to interact with IGFBP3 and transferrin. Insulin-like growth factor 2 receptor Insulin-like growth factor II IRES...
    15 KB (1,932 words) - 08:59, 2 November 2024
  • Thumbnail for Brain-derived neurotrophic factor
    responding to this growth factor, TrkB (pronounced "Track B") and the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). It may...
    46 KB (5,344 words) - 17:28, 12 October 2024
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,708 words) - 22:30, 15 October 2024
  • Thumbnail for Fibroblast growth factor 21
    and ketogenesis. FGF21 stimulates phosphorylation of fibroblast growth factor receptor substrate 2 and ERK1/2 in the liver. Acute FGF21 treatment induced...
    24 KB (3,038 words) - 18:36, 14 July 2024
  • Thumbnail for Fibroblast growth factor 2
    specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was first...
    22 KB (2,698 words) - 17:05, 16 July 2024