Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic...
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of chemotherapy resistance, particularly to the chemotherapy drug, L-asparaginase. Escherichia coli derived asparagine synthetase is a dimeric protein...
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(1st ed.). Wiley. ISBN 978-0-470-40753-0. "Isolation and screening of L-asparaginase free of glutaminase and urease from fungal sp". researchgate.net. 22...
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thiazide diuretics, statins, niacin, pentamidine, protease inhibitors, L-asparaginase, and antipsychotics. The acute administration of stimulants such as...
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enzyme L-asparaginase II conjugated with succinimidyl carbonate monomethoxypolyethylene glycol (pegol). The L-asparaginase portion hydrolyzes L-asparagine...
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include L-asparaginase or cyclophosphamide. For children with low-risk ALL, standard therapy usually consists of three drugs (prednisone, L-asparaginase, and...
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L-asparaginase for the treatment of acute lymphoblastic leukemia in patients who are hypersensitive to the native unmodified form of L-asparaginase (Enzon...
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bacterial asparaginases: I. Isolation and characterization of a tumor inhibitory asparaginase from Alcaligenes Eutrophus. II. Insolubilization of L-Asparaginase...
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either CHOP plus L-asparaginase or, alternatively, SMILE (i.e. dexamethasone, methotrexate, leucovorin, ifosfamide, L-Asparaginase, and etoposide. However...
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L-asparaginase is an enzyme that in humans is encoded by the ASRGL1 gene. The ASRGL1 protein consists of 308 amino acids and is activated by autocleavage...
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Khan AA, Shrivastav A, Jain SK, Singhal PK (2012). "Kinetic studies of L-asparaginase from Penicillium digitatum". Preparative Biochemistry & Biotechnology...
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"Solid-State Fermentation vs Submerged Fermentation for the Production of l-Asparaginase". Advances in Food and Nutrition Research. 78: 115–135. doi:10.1016/bs...
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It is also used to induce remission in ALL with dexamethasone and L-asparaginase, and in combination with prednisone to treat childhood leukemia. Vincristine...
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N4-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26, aspartylglucosylamine deaspartylase, aspartylglucosylaminase, aspartylglucosaminidase, aspartylglycosylamine...
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immunosuppressants cyclosporin A and tacrolimus, the leukemia drug L-asparaginase, and the antibiotic gatifloxicin. Diabetes is typically diagnosed by...
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initial induction therapy, including a glucocorticoid, vincristine, L-asparaginase, and an anthracycline for 4 to 6 weeks,followed by intensive combination...
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efficacy of a combination chemotherapy regimen consisting of methotrexate, L-asparaginase, idarubicin, and dexamethasone followed by allogenic or autologous bone...
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CHOP-like regimens. Subsequent studies discovered that L-asparaginase (NK cells do not express L-asaraginase) and, to a lesser extent, platinum-based antineoplastic...
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cyclophosphamide, hydroxycarbamide, doxorubicin, mitoxantrone, and L-asparaginase, although combinations of different agents are more promising. According...
44 KB (5,640 words) - 16:03, 25 April 2024
treatment is a combination of cyclophosphamide, vincristine, prednisone, L-asparaginase, and doxorubicin. Other chemotherapy drugs such as chlorambucil, lomustine...
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(1973) Doxorubicin (Adriamycin) (1974) Mitomycin C (Mutamycin) (1974) L-Asparaginase (Elspar) (1978) Daunomycin (Cerubidine) (1979) VP-16-213 (Etoposide)...
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ART5: encoding protein Adp-ribosyltransferase 5 ASRGL1: encoding enzyme L-asparaginase ATM: ataxia telangiectasia mutated (includes complementation groups...
28 KB (1,930 words) - 22:58, 28 March 2024
a sugar kinase, fraA a fructose-asparagine transporter, and fraE a L-asparaginase. Notably, mutations in fraB cause the buildup of the toxic intermediate...
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1971). "The in vivo effects of semipermeable microcapsules containing L-asparaginase on 6C3HED lymphosarcoma". Nature. 229 (5280): 117–118. Bibcode:1971Natur...
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Culture Conditions for Production of the Anti-Leukemic Glutaminase Free L-Asparaginase by Newly Isolated NEAE-119 Using Response Surface Methodology". BioMed...
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PMID 10825154. Jerebzoff-Quintin, Simonne; Jerebzoff, Stephan (1985). "L-Asparaginase activity in Leptosphaeria michotii. Isolation and properties of two...
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single course of intensification therapy consisting of cytarabine and L-asparaginase, and concluded with a central nervous system consolidation course of...
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Ortlund E, Lacount MW, Lewinski K, Lebioda L (February 2000). "Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine...
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(2005-09-01). "Selective apoptosis of natural killer-cell tumours by l-asparaginase". British Journal of Haematology. 130 (6): 860–868. doi:10.1111/j.1365-2141...
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The halotolerant Cobetia amphilecti AMI6 produces glutaminase-free L-asparaginase (CobAsnase) with a molecular mass of 37 kDa on SDS-PAGE. The purified...
2 KB (276 words) - 18:00, 27 April 2024