Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. It is called "non-homologous" because the break ends are directly...

Non-homologous end-joining factor 1 (NHEJ1), also known as Cernunnos or XRCC4-like factor (XLF), is a protein that in humans is encoded by the NHEJ1 gene...

cells, there are two main DSB repair mechanisms: Homologous recombination (HR) and non-homologous end joining (NHEJ). HR relies on undamaged template DNA as...

strand breaks, mainly non-homologous end joining (NHEJ), homologous recombination (HR), and MMEJ. NHEJ directly joins both ends of the double strand break...

repair of double strand breaks by homologous recombination or non-homologous end joining, repair of single nucleotide damages by base excision repair, and...

double-strand breaks (DSBs): non-homologous end joining (NHEJ), microhomology-mediated end joining (MMEJ), and homologous recombination (HR): In NHEJ,...

transferase (TdT), and Artemis nuclease, a member of the ubiquitous non-homologous end joining (NHEJ) pathway for DNA repair. Several other enzymes are known...

CpG sites within the double-strand break-associated insertion. Non-homologous end joining (NHEJ) repair of a double-strand break can cause a small number...

pathways by which this will occur is the repair mechanism known as non-homologous end joining (NHEJ). Illegitimate recombination is a natural process which...

proteins that have key roles in the DNA repair processes of non-homologous end joining and homologous recombination. Mouse cells deficient for maturation of...

Non-allelic homologous recombination (NAHR) is a form of homologous recombination that occurs between two lengths of DNA that have high sequence similarity...

be repaired through homologous recombination, polymerase theta-mediated end joining (TMEJ) or through non-homologous end joining (NHEJ). NHEJ is a DNA...

breaks Blunt ends Non-homologous end joining Nucleotide Cell cycle Telomere NHEJ Homologous Recombination Microhomology-mediated end joining Jimeno S, Mejías-Navarro...

to tether broken ends prior to repair by non-homologous end joining or to initiate DNA end resection prior to repair by homologous recombination. The...

double-strand breaks are introduced into the sperm DNA. The conventional non-homologous end joining pathway for repairing double-strand breaks is not available for...

relies on Ku to direct it to DNA ends and trigger its kinase activity. DNA-PKcs is required for the non-homologous end joining (NHEJ) pathway of DNA repair...

the absence of non-homologous end joining, free ends of DNA may be rejoined by an alternative pathway biased toward microhomology joins. With the exception...

breakage-induced replication. When the homologous DNA is absent, another process called non-homologous end joining (NHEJ) takes place instead. HDR is important...

that nonhomologous or microhomologous repair mechanisms such as non-homologous end joining (NHEJ) and microhomology-mediated break induced repair (MMBIR)...

deficient in the ability to repair double-strand breaks by the non-homologous end joining (NHEJ) pathway are more sensitive to prolonged desiccation during...

Overexpression of HMGA2 delayed the release of DNA-PKcs (needed for non-homologous end joining DNA repair) from double strand break sites. Overexpression of...

double-strand break repair by an imprecise processes such as non-homologous end joining. Chromosome instability in chronic myeloid leukemia may be due...

repetitive sequences, or through chromosomal breakage followed by non-homologous end joining. Inversions are of two types: paracentric and pericentric. Paracentric...

sequences, the repair of DNA damage by the processes of homologous recombination, non-homologous end joining, DNA mismatch repair or base excision repair may...

repair pathways: theta-mediated end joining (TMEJ). Most double-strand breaks are repaired by non-homologous end joining (NHEJ) or homology directed repair...

inhibition by Ara-CTP of the DNA non-homologous end joining pathway. Thus transient DNA breakage followed by non-homologous end joining appear to be necessary steps...

including repair of DNA double-strand breaks (DSBs) by the process of non-homologous end joining The repair function of alpha-synuclein appears to be greatly reduced...

plants. hXRCC4 is one of several core proteins involved in the non-homologous end joining (NHEJ) pathway to repair DNA double strand breaks (DSBs). NHEJ...

complex that binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. Ku is evolutionarily...

inactivation or the introduction of heterologous genes through non-homologous end joining and homologous recombination respectively in many laboratory model organisms...