Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of...

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products...

the regulation of gene expression. Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA...

Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. Gene silencing can occur during either transcription...

In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by...

segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression...

List of cis-regulatory RNA elements Polyadenylation signals, mRNA AU-rich element, mRNA Other Regulation of gene expression Cis-trans isomerism Gene regulatory...

proliferation. This gene also has a role in the formation of some cancers and in the regulation of gene expression. The H19 gene is expressed exclusively...

Post-transcriptional regulation is the control of gene expression at the RNA level. It occurs once the RNA polymerase has been attached to the gene's promoter and...

promoter regions of signal-regulated genes. These DSBs allow rapid up-regulation of expression of such signal responsive genes in a number of systems (see...

However, the amount of gene product produced in a cell is more commonly dependent on regulation of gene expression. The normal gene dosage is dependent on...

modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA processing. In vitro methylation of tissue samples...

substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell. GRN also play a central...

master regulator of mitochondrial biogenesis. PGC-1α is also the primary regulator of liver gluconeogenesis, inducing increased gene expression for gluconeogenesis...

such as gene transcription, translation, regulation of gene expression and protein–protein interactions, as opposed to the static aspects of the genomic...

source of genetic variability. They seem to play a particularly important role in the regulation of gene expression and the creation of RNA genes. This...

of high grade, ductal breast cancers. It has long been noted that loss of BRCA1 activity, either by germ-line mutations or by down-regulation of gene...

Spatiotemporal gene expression is the activation of genes within specific tissues of an organism at specific times during development. Gene activation patterns...

Its primary mode of action is the regulation of the iron storage hormone hepcidin. It is possible to delete part or all of a gene of interest in mice...

regulating the expression of adjacent genes; hence these receptors are classified as transcription factors. The regulation of gene expression by nuclear receptors...

operon is an example of repressible negative regulation of gene expression. The repressor protein binds to the operator in the presence of tryptophan (repressing...

heavily on proper expression of the SHH gene and subsequent sonic hedgehog protein, earning it the distinction of being an essential gene to development...

RbAp46/48, and PCL). Mutation or over-expression of EZH2 has been linked to many forms of cancer. EZH2 inhibits genes responsible for suppressing tumor development...

Bedi A (January 2000). "Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha". Genes & Development. 14 (1): 34–44...

involved in regulating gene expression, an important process in synaptic plasticity. Glutamate binding to NMDA upregulates the production of N-cadherin’s intracellular...

MeCP2 has been implicated in regulation of imprinted genes and loci that include UBE3A and DLX5. Reduced expression of MECP2 in Mecp2+/- neural stem...

transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can...

deletion of the kir6.2 or sur2 genes leads to coronary artery vasospasm and death. Upon further exploration of sarcKATP's role in cardiac rhythm regulation, it...

genetics, a regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences...

circadian rhythmicity of the gene's expression. CRE/CREB-mediated regulation of the AVP gene is activated through the cAMP activation of Ras signaling pathways...