• Thumbnail for Ciclosporin
    Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is taken orally or intravenously...
    57 KB (5,350 words) - 21:25, 11 November 2024
  • Thumbnail for Immunosuppressive drug
    corticosteroids. The most frequent combination is to use antibodies and ciclosporin simultaneously in order to prevent patients from gradually developing...
    29 KB (3,378 words) - 02:54, 25 September 2024
  • Thumbnail for Pyoderma gangrenosum
    gangrenosum is not infectious. Treatments may include corticosteroids, ciclosporin, infliximab, or canakinumab. The disease was identified in 1930. It affects...
    14 KB (1,417 words) - 05:19, 12 August 2024
  • Thumbnail for Dry eye syndrome
    suggested to help treat the condition. The immunosuppressant cyclosporine (ciclosporin) may be recommended to increase tear production and, for short term use...
    62 KB (6,352 words) - 09:15, 11 November 2024
  • General: diuretics, β-blockers, vasodilator agents Local: ACE inhibitors, ciclosporin, tacrolimus. Proximal convoluted tubule: Aminoglycoside antibiotics (e...
    6 KB (521 words) - 16:43, 13 February 2024
  • Thumbnail for Hair loss
    Hair loss, also known as alopecia or baldness, refers to a loss of hair from part of the head or body. Typically at least the head is involved. The severity...
    48 KB (5,558 words) - 18:18, 2 November 2024
  • Thumbnail for Methylprednisolone
    Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive...
    57 KB (5,143 words) - 05:47, 15 October 2024
  • anti-thymocyte globulin—combined with corticosteroids, chemotherapy, and ciclosporin. Hematopoietic stem cell transplantation is also used, especially for...
    40 KB (4,353 words) - 10:50, 24 October 2024
  • Thumbnail for Trichodysplasia spinulosa
    spinulosa, viral-associated trichodysplasia, pilomatrix dysplasia and ciclosporin-induced folliculodystrophy, although the last is a misnomer) is a rare...
    15 KB (1,480 words) - 06:34, 1 January 2024
  • Ciclosporin is a cyclic polypeptide that has been used widely as an orally-available immunosuppressant. It was originally used to prevent transplant rejection...
    21 KB (2,276 words) - 18:52, 20 November 2023
  • Thumbnail for Grapefruit–drug interactions
    metabolism to morphine entirely by CYP2D6. Ciclosporin (cyclosporine, Neoral): Blood levels of ciclosporin are increased if taken with grapefruit juice...
    54 KB (5,664 words) - 00:01, 10 November 2024
  • Thumbnail for Tacrolimus
    500,000 prescriptions. It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated...
    43 KB (4,357 words) - 08:39, 29 October 2024
  • Thumbnail for Cyclic peptide
    novel oral medications. Examples include: Amanitins Bacitracin Colistin Ciclosporin Dactinomycin Daptomycin Gramicidin S Hymenistatin Microcystins Nisin...
    9 KB (981 words) - 18:07, 25 September 2024
  • Thumbnail for Lercanidipine
    inhibitors of the liver enzyme CYP3A4 or with the immunosuppressant drug ciclosporin. Lercanidipine is generally well tolerated; no single adverse effect...
    15 KB (1,415 words) - 11:56, 29 September 2024
  • allogeneic renal transplantation. It is to be used concomitantly with ciclosporin for microemulsion- and corticosteroid-based immunosuppression, in people...
    9 KB (587 words) - 12:00, 30 September 2024
  • Thumbnail for Fungus
    specific desirable properties. Other antibiotics produced by fungi include: ciclosporin, commonly used as an immunosuppressant during transplant surgery; and...
    200 KB (19,205 words) - 21:46, 10 November 2024
  • Thumbnail for Trimethoprim/sulfamethoxazole
    while on co-trimoxazole Ciclosporin — patients who have received a kidney transplant and are receiving co-trimoxazole and ciclosporin concomitantly are at...
    49 KB (4,070 words) - 11:37, 11 November 2024
  • that, under certain conditions, produces the immunosuppressant drug ciclosporin. In its sexual stage (teleomorph) it is a parasite on scarab beetles...
    17 KB (1,735 words) - 18:06, 4 November 2024
  • Thumbnail for Statin
    ciclosporin Pravastatin or fluvastatin Drug interactions are possible, but studies have not shown that these statins increase exposure to ciclosporin...
    134 KB (13,062 words) - 13:35, 14 October 2024
  • Thumbnail for Leukopenia
    Immunosuppressive drugs, such as sirolimus, mycophenolate mofetil, tacrolimus, ciclosporin, leflunomide and TNF inhibitors, have leukopenia as a known complication...
    9 KB (810 words) - 17:18, 30 September 2024
  • Commonly used agents are prednisone, mycophenolate, cyclophosphamide, ciclosporin, tacrolimus, everolimus, thymoglobulin and sirolimus. Newer, so-called...
    25 KB (2,838 words) - 02:41, 5 October 2024
  • Thumbnail for Pharmacokinetics
    to (or can be ascribed to). An example is the relaunch of the use of ciclosporin as an immunosuppressor to facilitate organ transplant. The drug's therapeutic...
    46 KB (4,510 words) - 13:42, 23 September 2024
  • Thumbnail for Cirrhosis
    transplantation. Transplantation necessitates the use of immune suppressants (ciclosporin or tacrolimus). Manifestations of decompensation in cirrhosis include...
    118 KB (12,408 words) - 06:11, 11 November 2024
  • Thumbnail for Novartis
    carcinoma Ritalin (methylphenidate) ADHD 554 2012 1% Sandimmune/Neoral (ciclosporin) Prevention of transplant rejection 821 2012 −9% Sandostatin (octreotide)...
    144 KB (12,146 words) - 09:25, 31 October 2024
  • Thumbnail for Ezetimibe
    statin. Ezetimibe may have significant medication interactions with ciclosporin and with fibrates other than fenofibrate. Common adverse drug reactions...
    20 KB (1,874 words) - 10:04, 21 October 2024
  • Thumbnail for Disease-modifying antirheumatic drug
    induce apoptosis of inflammatory cells and decrease chemotaxis unknown ciclosporin (Cyclosporin A) calcineurin inhibitor unknown D-penicillamine (seldom...
    10 KB (854 words) - 06:50, 2 November 2024
  • Thumbnail for Methotrexate
    Baron S, Browne F, et al. (November 2023). "Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children...
    37 KB (3,397 words) - 01:51, 12 November 2024
  • Thumbnail for Immunosuppression
    specific[vague] azathioprine was identified in 1960, but it was the discovery of ciclosporin in 1980 (together with azathioprine) that allowed significant expansion...
    10 KB (938 words) - 16:41, 3 December 2023
  • Thumbnail for Psoriasis
    include methotrexate, ciclosporin, hydroxycarbamide, fumarates such as dimethyl fumarate, and retinoids. Methotrexate and ciclosporin are medications that...
    116 KB (13,061 words) - 15:20, 6 November 2024
  • Thumbnail for Mefenamic acid
    their excretion via the kidneys. It can increase the kidney toxicity of ciclosporin and tacrolimus. Combination with antihypertensive drugs such as ACE inhibitors...
    26 KB (2,513 words) - 05:24, 22 October 2024