Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects...
25 KB (3,269 words) - 20:18, 15 January 2024
Pharmacodynamics (section Toxicodynamics)
Pharmacokinetics and pharmacodynamics are termed toxicokinetics and toxicodynamics in the field of ecotoxicology. Here, the focus is on toxic effects on...
19 KB (2,225 words) - 21:08, 29 May 2024
Abrin (section Toxicodynamics)
Abrin is an extremely toxic toxalbumin found in the seeds of the rosary pea (or jequirity pea), Abrus precatorius. It has a median lethal dose of 0.7 micrograms...
19 KB (2,291 words) - 00:11, 13 June 2024
Latrotoxin (section Toxicodynamics)
A latrotoxin is a high-molecular mass neurotoxin found in the venom of spiders of the genus Latrodectus (widow spiders) as well as at least one species...
17 KB (2,274 words) - 00:42, 29 June 2024
In toxicodynamics and pharmacodynamics, Loewe additivity (or dose additivity) is one of several common reference models used for measuring the effects...
4 KB (571 words) - 11:04, 31 October 2023
Bifenthrin (section Toxicodynamics)
Bifenthrin is a pyrethroid insecticide. It is widely used against ant infestations. Bifenthrin is poorly soluble in water and often remains in soil. Its...
18 KB (1,940 words) - 21:03, 23 August 2024
Lead poisoning (section Toxicodynamics)
through the feces, and very small amounts in hair, nails, and sweat. Toxicodynamics describes how the toxin affects the body, including the mechanisms causing...
198 KB (21,311 words) - 19:59, 26 September 2024
Cadmium poisoning (section Toxicodynamics)
Cadmium is a naturally occurring toxic metal with common exposure in industrial workplaces, plant soils, and from smoking. Due to its low permissible exposure...
22 KB (2,624 words) - 01:01, 2 October 2024
toxic effects, toxicokinetics can be combined with toxicodynamics. Such toxicokinetic-toxicodynamic (TKTD) models are used in ecotoxicology (see ecotoxmodels...
4 KB (468 words) - 21:15, 20 July 2022
Fumonisin B1 (section Toxicodynamics)
Fumonisin B1 is the most prevalent member of a family of toxins, known as fumonisins, produced by multiple species of Fusarium molds, such as Fusarium...
27 KB (3,202 words) - 14:45, 18 September 2024
Bolon, Brad (eds.), "Chapter 4 - Principles of Pharmacodynamics and Toxicodynamics", Fundamentals of Toxicologic Pathology (Third Edition), Academic Press...
6 KB (625 words) - 00:59, 6 June 2024
Benoxaprofen (section Toxicodynamics)
Benoxaprofen, also known as Benoxaphen, is a chemical compound with the formula C16H12ClNO3. It is a non-steroidal anti-inflammatory drug (NSAID) of the...
24 KB (2,663 words) - 17:28, 7 September 2024
particulate matter and carbon black are very diverse and each has different toxicodynamics, detailed mechanisms of translocation are not clear. Water-soluble fractions...
29 KB (2,820 words) - 11:00, 12 September 2024
Hexachlorocyclopentadiene (section Toxicodynamics)
Hexachlorocyclopentadiene (HCCPD), also known as C-56, Graphlox, and HRS 1655, is an organochlorine compound with the formula C5Cl6. It is a precursor...
22 KB (2,929 words) - 15:53, 8 May 2024
Protoxin-I (section Toxicodynamics)
Protoxin-I, also known as ProTx-I, or Beta/omega-theraphotoxin-Tp1a, is a 35-amino-acid peptide neurotoxin extracted from the venom of the tarantula Thrixopelma...
16 KB (1,797 words) - 03:30, 2 May 2024
Apamin (section Toxicodynamics)
Apamin is an 18 amino acid globular peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks...
19 KB (1,992 words) - 22:36, 21 August 2024
Leptophos (section Toxicodynamics)
Leptophos (O-(4-bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate) belongs to the organophosphates and at room temperature it is a stable white...
14 KB (1,183 words) - 08:48, 23 December 2023
Batroxobin (section Toxicodynamics and reactivity)
Batroxobin, also known as reptilase, is a snake venom enzyme with Venombin A activity produced by Bothrops atrox and Bothrops moojeni, venomous species...
15 KB (2,037 words) - 21:44, 18 October 2023
Arenobufagin (section Toxicodynamics)
Arenobufagin is a cardiotoxic bufanolide steroid secreted by the Argentine toad Bufo arenarum. It has effects similar to digitalis, blocking the Na+/K+...
13 KB (1,536 words) - 00:10, 8 August 2024
2001). "The toxicology of microcystin-LR: occurrence, toxicokinetics, toxicodynamics, diagnosis and treatment". Veterinary and Human Toxicology. 43 (5):...
104 KB (11,579 words) - 19:29, 18 September 2024
2011). "General unified threshold model of survival--a toxicokinetic-toxicodynamic framework for ecotoxicology". Environmental Science & Technology. 45...
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amine-associated receptor 1 (hTAAR1). It has comparable pharmacodynamic and toxicodynamic properties to that of phenethylamine, amphetamine, and other methylphenethylamines...
10 KB (1,125 words) - 02:12, 22 April 2024
et al. (2020). "Vancomycin-Induced Kidney Injury: Animal Models of Toxicodynamics, Mechanisms of Injury, Human Translation, and Potential Strategies for...
83 KB (8,190 words) - 02:52, 25 October 2024
mathematical models in ecotoxicology, with emphasis on toxicokinetic-toxicodynamic models CDD Vault, Example of Dose-Response Curve fitting software...
17 KB (1,788 words) - 21:35, 5 September 2024
(355 nm) or N2 (337 nm) laser for ionization. Pharmacodynamics and toxicodynamics in tissue have been studied by MALDI imaging. Desorption electrospray...
28 KB (3,322 words) - 17:12, 26 May 2024
Retrieved 31 May 2019. Kretschmann, Andreas; et al. (2011). "Mechanistic Toxicodynamic Model for Receptor-Mediated Toxicity of Diazoxon, the Active Metabolite...
20 KB (2,154 words) - 19:03, 14 May 2024
Morse, Bridget L.; Morris, Marilyn E. (2013-06-28). "Toxicokinetics/Toxicodynamics ofγ-Hydroxybutyrate-Ethanol Intoxication: Evaluation of Potential Treatment...
32 KB (3,618 words) - 16:27, 24 October 2024
Ehsan; Arjmand, Abdollah; Pourahmad, Jalal (December 2019). "A Review on Toxicodynamics of Depleted Uranium". Iranian Journal of Pharmaceutical Research. 18...
31 KB (3,754 words) - 06:56, 20 September 2024
humans and animals (as appropriate), the substance's toxicokinetics and toxicodynamics (including carry-over of the toxic substance from feed to edible animal...
7 KB (829 words) - 06:20, 20 February 2024
2003, The Bayesian population approach to physiological toxicokinetic-toxicodynamic models – An example using the MCSim software, Toxicology Letters 138:143-150...
7 KB (989 words) - 04:39, 1 January 2024