Tyrosinase is an oxidase that is the rate-limiting enzyme for controlling the production of melanin. The enzyme is mainly involved in two distinct reactions...

complex process involving the enzyme tyrosinase. Mammals have a gene that codes for the presence of tyrosinase in cells – called the TYR gene. If this...

Tyrosinase-related protein 1, also known as TYRP1, is an intermembrane enzyme which in humans is encoded by the TYRP1 gene. Tyrp1 is a melanocyte-specific...

"Oculocutaneous albinism type 1B associated with a functionally significant tyrosinase gene polymorphism detected with Whole Exome Sequencing". Ophthalmic Genetics...

arbutin (β-arbutin), and like the β-form it is an enzyme inhibitor of human tyrosinase. α-Arbutin is used in the cosmetic and pharmaceutical industries for its...

often associated with the TYR gene, which controls the production of the tyrosinase enzyme that produces melanin. The color point allele is at the C locus...

oculocutaneous albinism that is caused by a dysfunction in the gene for tyrosinase (symbol TYR or OCA1). The location of OCA1 may be written as "11q1.4–q2...

l-DOPA are all precursors to the biological pigment melanin. The enzyme tyrosinase catalyzes the oxidation of l-DOPA to the reactive intermediate dopaquinone...

action of PPOs to form o-quinone. Hence, PPOs may also be referred to as tyrosinases. Common foods producing the enzyme include mushrooms (Agaricus bisporus)...

of tyrosinase: The catalytic action of tyrosinase is inhibited by the skin whitening agent. Inhibition of the expression or activation of tyrosinase: The...

all vertebrates, including humans. It is due to absence or defect of tyrosinase, a copper-containing enzyme involved in the production of melanin. Unlike...

hyperpigmentation issues. Its mechanism of action involves inhibiting the activity of tyrosinase, an essential enzyme for melanin synthesis in the human skin, thereby...

believed to be related to the enzyme tyrosinase which produces melanin. Among several chemicals known to inhibit tyrosinase production, such as hydroquinone...

being a component of a number of hair and skin conditioners. AzA inhibits tyrosinase. Azelaic acid is industrially produced by the ozonolysis of oleic acid...

OCA1A, which impairs tyrosinase production. In other mammals, the diagnosis of albinism is based on the impairment of tyrosinase production through defects...

regulated by the microphthalmia-associated transcription factor (MITF). Tyrosinase-related protein 1 (TYRP1) Dopachrome, a cyclization product of L-DOPA...

Tyrosinemia type II is an autosomal recessive condition with onset between ages 2 and 4 years, when painful circumscribed calluses develop on the pressure...

Poly-γ-glutamate is a metabolite of Bacillus subtilis. Poly-γ-glutamate inhibits tyrosinase and melanogenesis in vitro. Liu, X.; Liu, F.; Liu, S.; Li, H.; Ling, P...

albinism, resulting from a mutation in tyrosinase, an enzyme involved in melanin production. The mutated tyrosinase enzyme is heat-sensitive; it fails to...

Studies have shown that the reduced pigment comes from a mutation in the gene for tyrosinase, the same as causes Type I oculocutaneous albinism in humans....

organelles called melanosomes. This reaction is catalyzed by the enzyme tyrosinase. The initial product, dopaquinone can transform into either 5,6-dihydroxyindole...

Mutations in the genes microphthalmia-associated transcription factor and tyrosinase are possibly responsible for the colour of manes. It starts growing when...

is often but not always related to the TYR gene coding the tyrosinase enzyme. Tyrosinase is required for melanocytes to produce melanin from the amino...

Rhododendron. The phenolic compound was first developed in 2010 as a tyrosinase inhibitor for skin-lightening cosmetics. In 2013, after rhododendrol reportedly...

Oculocutaneous albinism type 3 Oculocutaneous albinism, tyrosinase negative Oculocutaneous albinism, tyrosinase positive Oculocutaneous tyrosinemia Oculodental...

an albino phenotype may be caused by a mutation in the gene encoding tyrosinase which is a key enzyme in melanin formation. However, exposure to UV radiation...

Stevens G, Zwane E, Kromberg J, Farrall M, et al. (October 1992). "The tyrosinase-positive oculocutaneous albinism locus maps to chromosome 15q11.2-q12"...

Robinson-Laverick, S. M.; Paton, D.; Jarman, S. N. (2011). "Variation in the Tyrosinase Gene Associated with a White Humpback Whale (Megaptera novaeangliae)"...

example of such a protein is the enzyme tyrosinase, which is required for melanin production. Normally tyrosinase is produced in minute quantities but its...

pigments called melanins, commonly associated with a genetic loss of tyrosinase function. Amelanism can affect fish, amphibians, reptiles, birds, and...