Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
40 KB (4,580 words) - 05:24, 3 June 2024
Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth...
24 KB (3,053 words) - 02:36, 28 March 2024
Vascular endothelial growth factor B also known as VEGF-B is a protein that, in humans, is encoded by the VEGF-B gene. VEGF-B is a growth factor that belongs...
14 KB (1,558 words) - 02:03, 27 November 2023
while fibroblast growth factors and vascular endothelial growth factors stimulate blood vessel differentiation (angiogenesis). Growth factor is sometimes...
10 KB (1,131 words) - 19:14, 31 March 2024
Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor...
27 KB (3,104 words) - 23:27, 27 March 2024
VEGF receptor (redirect from Receptors, vascular endothelial growth factor)
VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
8 KB (755 words) - 18:51, 2 November 2023
trophoblast. The placental growth factor (PGF) gene is a protein-coding gene and a member of the vascular endothelial growth factor (VEGF) family. The PGF...
15 KB (1,923 words) - 12:01, 27 September 2023
Anti-VEGF (redirect from Anti vascular endothelial growth factor therapy)
Anti–vascular endothelial growth factor therapy, also known as anti-VEGF (/vɛdʒˈɛf/) therapy or medication, is the use of medications that block vascular endothelial...
14 KB (1,671 words) - 12:47, 23 April 2024
C-fos-induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded...
10 KB (1,253 words) - 05:14, 9 February 2024
family represents the vascular endothelial growth factor (VEGF) internal ribosome entry site (IRES) A. VEGF is an endothelial cell mitogen with many...
2 KB (123 words) - 05:06, 10 October 2019
domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. KDR is...
6 KB (794 words) - 11:50, 18 May 2022
vascular endothelial growth factors B and C (VEGF-B, VEGF-C) which are active in angiogenesis and endothelial cell growth, and placenta growth factor...
24 KB (2,877 words) - 10:08, 2 June 2024
Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is protein that in humans...
10 KB (1,378 words) - 23:28, 27 March 2024
Endothelium (redirect from Vascular endothelial cells)
are called vascular endothelial cells whereas those in direct contact with lymph are known as lymphatic endothelial cells. Vascular endothelial cells line...
27 KB (2,992 words) - 20:50, 1 July 2024
Angiogenesis (redirect from Vascularized)
secrete vascular endothelial growth factor (VEGF-A) which is a proangiogenic growth factor. These biological signals activate receptors on endothelial cells...
49 KB (5,763 words) - 10:02, 2 June 2024
Bevacizumab (category Chemicals that do not have a ChemSpider ID assigned)
slowing the growth of new blood vessels by inhibiting vascular endothelial growth factor A (VEGF-A), in other words anti–VEGF therapy. Bevacizumab was approved...
74 KB (6,565 words) - 05:35, 13 June 2024
Angiogenesis inhibitor (redirect from Antiangiogenesis factor)
paracrine factors (including angiogenin, vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and transforming growth factor-β (TGF-β)...
33 KB (3,229 words) - 04:14, 17 June 2024
Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. FLT1 is a member of VEGF receptor gene family. It...
9 KB (1,086 words) - 00:25, 5 October 2022
Bates, D. O. & Harper, S. J. Regulation of vascular permeability by vascular endothelial growth factors. Vascul Pharmacol 39, 225-237 (2002) Patlak,...
4 KB (469 words) - 15:49, 27 July 2023
Aflibercept (category Chemicals that do not have a ChemSpider ID assigned)
developed by Regeneron Pharmaceuticals. It is an inhibitor of vascular endothelial growth factor (VEGF). Aflibercept (Eylea) is indicated for the treatment...
26 KB (1,884 words) - 19:14, 28 June 2024
Neuropilin (category Protein pages needing a picture)
and Vascular Endothelial Growth Factor (VEGF) receptors/VEGF ligands, respectively. Neuropilins predominantly act as co-receptors as they have a very...
11 KB (1,055 words) - 03:34, 23 June 2024
reason intravitreal injections are used is to administer anti-vascular endothelial growth factor (anti-VEGF) therapies to treat wet age related macular degeneration...
19 KB (2,323 words) - 20:58, 30 April 2024
the growth of new blood vessels from the pre-existing vasculature. FGF1 and FGF2 are more potent angiogenic factors than vascular endothelial growth factor...
25 KB (3,123 words) - 20:10, 26 April 2024
Recentin) is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases. The drug is being developed by AstraZeneca as a possible...
8 KB (644 words) - 19:21, 20 December 2023
Protein kinase inhibitor (redirect from Vascular endothelial growth factor receptor tyrosine kinase inhibitor)
Archived from the original on 2008-05-11. Jänne, Pasi A.; Gray, Nathanael; Settleman, Jeff (2009). "Factors underlying sensitivity of cancers to small-molecule...
23 KB (742 words) - 04:57, 30 December 2023
TGF beta 1 (redirect from Transforming growth factor-β1)
Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein...
19 KB (2,290 words) - 20:43, 26 March 2024
human neuropilins. NRP1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (for example, VEGFA) and...
16 KB (1,958 words) - 17:08, 8 June 2024
diarrhea. It is a small molecule tyrosine-kinase inhibitor, targeting vascular endothelial growth factor receptor, fibroblast growth factor receptor and...
34 KB (3,010 words) - 05:48, 22 May 2024
Brolucizumab (category Chemicals that do not have a ChemSpider ID assigned)
was designed to attach to and block a substance called vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein that makes blood vessels grow...
14 KB (1,121 words) - 07:47, 19 June 2024
responsive to factors including platelet-derived growth factor B (PDGFB) and vascular endothelial growth factor (VEGF). The weakness and disorganization of...
5 KB (564 words) - 06:05, 15 November 2023