Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, activin enhances...
26 KB (2,557 words) - 08:59, 5 August 2024
Inhibin, beta A, also known as INHBA, is a protein which in humans is encoded by the INHBA gene. INHBA is a subunit of both activin and inhibin, two closely...
9 KB (1,109 words) - 18:55, 11 April 2024
INHA (redirect from Inhibin-alpha)
"Characterization and determination of the biological activities of noncleavable high molecular weight forms of inhibin A and activin A". Mol. Endocrinol...
9 KB (1,000 words) - 18:54, 11 April 2024
Hypogonadism (category Gonadotropin-releasing hormone and gonadotropins)
progesterone, DHEA, anti-Müllerian hormone, activin, and inhibin. Sperm development (spermatogenesis) and release of the egg from the ovaries (ovulation)...
25 KB (2,614 words) - 22:07, 6 September 2024
activin and inhibin, myostatin, anti-Müllerian hormone (AMH), and NODAL. TGFβ family receptors are grouped into three types, type I, type II, and type...
5 KB (468 words) - 03:56, 29 November 2023
Transforming growth factor beta superfamily (category Developmental genes and proteins)
morphogenetic proteins and the growth differentiation factors The activin and inhibin subfamilies The left-right determination factors A group encompassing...
7 KB (595 words) - 13:39, 10 September 2024
transducer of activin or activin-like ligands (e.g., inhibin) signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. These go on...
12 KB (1,542 words) - 05:48, 28 March 2024
location and ACVR2A gene details page in the UCSC Genome Browser. Welt CK (2002). "The physiology and pathophysiology of inhibin, activin and follistatin...
12 KB (1,427 words) - 20:41, 13 August 2023
(June 2002). "Expression and localization of inhibin alpha, inhibin/activin betaA and betaB and the activin type II and inhibin beta-glycan receptors in...
6 KB (583 words) - 15:40, 29 March 2023
chromosome 11p13, and is expressed in gonadotropes of the pituitary cells, controlled by GnRH, inhibited by inhibin, and enhanced by activin.[citation needed]...
21 KB (2,261 words) - 03:48, 13 June 2024
and so the release of gonads. Inhibins and activins also regulate bone mass. Beall, C.; Ashford, M. L.; McCrimmon, R. J. (2011). "The physiology and pathophysiology...
4 KB (461 words) - 09:07, 29 January 2023
Macroorchidism (section Signs and symptoms)
therefore producing inhibin B which brings into play a negative feedback over the pituitary FSHB expression. The IGSF1 gene inhibits the activin A pathway which...
18 KB (1,858 words) - 03:18, 6 June 2024
Hypothalamic–pituitary–gonadal axis (category Gonadotropin-releasing hormone and gonadotropins)
spermatogenesis and inhibits the hypothalamus. Inhibin is produced by the spermatogenic cells, which, also through inactivating activin, inhibits the hypothalamus...
20 KB (2,454 words) - 08:21, 31 May 2024
binds with high affinity to free hemoglobin released from erythrocytes, and thereby inhibits its deleterious oxidative activity. Compared to Hp, hemopexin...
25 KB (2,863 words) - 09:58, 19 May 2024
Peptidoglycan (section Inhibition and degradation)
is a unique large macromolecule, a polysaccharide, consisting of sugars and amino acids that forms a mesh-like layer (sacculus) that surrounds the bacterial...
36 KB (4,018 words) - 15:22, 12 September 2024
involves the stomach, pancreas and small intestine, and is mediated by two carriers: Haptocorrin and intrinsic factor, and because Haptocorrin (transcobalamin...
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condom Accidental incest Acrosome Acrosome reaction Acrotomophilia Activin and inhibin Adolescent sexuality Adolescent sexuality in the United States Adult...
33 KB (3,525 words) - 10:24, 28 August 2024
cytosol and nucleus can be modified through the reversible addition of a single GlcNAc residue that is considered reciprocal to phosphorylation and the functions...
28 KB (2,653 words) - 04:14, 23 July 2024
Schaik RH, Themmen AP, de Jong FH (1997). "Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary...
11 KB (1,346 words) - 02:52, 22 July 2024
of MUC16 is its large size. MUC16 is more than twice as long as MUC1 and MUC4 and contains about 22,000 amino acids, making it the largest membrane-associated...
16 KB (1,916 words) - 18:26, 3 December 2023
sulfate and uronic acid groups. Proteoglycans occur in connective tissue. Proteoglycans are categorized by their relative size (large and small) and the nature...
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Teresa Woodruff (category Fellows of the American Academy of Arts and Sciences)
physiology of inhibin and activin in pituitary and ovarian function in rodent and the effects of recombinant human inhibin and activin in primates. Woodruff...
20 KB (1,915 words) - 06:35, 11 September 2024
Mucin (section Genes and proteins)
mineralization, including nacre formation in mollusks, calcification in echinoderms and bone formation in vertebrates. They bind to pathogens as part of the immune...
22 KB (2,309 words) - 12:39, 19 July 2024
An Activin receptor is a receptor which binds activin. These proteins are receptor-type kinases of Ser/Thr type, which have a single transmembrane domain...
2 KB (174 words) - 10:58, 22 March 2023
fungicide) and is part of the innate defense, mainly at mucoses. It is constantly produced and released into saliva, tears, as well as seminal and vaginal...
48 KB (5,690 words) - 06:26, 13 September 2024
produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Tg is secreted and accumulated at hundreds of grams per litre in...
17 KB (1,983 words) - 19:38, 30 June 2024
with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved...
4 KB (490 words) - 01:04, 4 March 2023
Liao AW, Ong CY, Flack NJ, Nicolaides KH (2001). "Maternal serum activin A and inhibin A in trisomy 18 pregnancies at 10-14 weeks". Prenat Diagn. 21 (7):...
12 KB (1,179 words) - 21:19, 28 March 2024
activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair...
14 KB (1,641 words) - 23:08, 5 September 2024