Potassium-chloride transporter member 5 (aka: KCC2 and SLC12A5) is a neuron-specific chloride potassium symporter responsible for establishing the chloride...

The chloride potassium symporter is a membrane transport protein of the solute carrier family 12 that is present in the S3-segment of the renal proximal...

Potassium-chloride transporter, member 4 is a chloride potassium symporter protein. It is encoded by the gene SLC12A4. Solute carrier family GRCh38: Ensembl...

potassium (K), and chloride (Cl) ions across the cell membrane. Because they move each solute in the same direction, they are considered symporters....

The sodium-chloride symporter (also known as Na+-Cl− cotransporter, NCC or NCCT, or as the thiazide-sensitive Na+-Cl− cotransporter or TSC) is a cotransporter...

Superfamily SLC12A9 SLC12A8 Chloride potassium symporter 5 Transporter Classification Database Saier, MH Jr. "2.A.30 The Cation-Chloride Cotransporter (CCC) Family"...

replacement. The symporter requires chloride to be transported in as well. Water passively follows to maintain isotonicity; excess chloride and potassium passively...

cotransport (secondary active transport) and include antiporters and symporters. In general, cotransporters consist of two out of the three classes of...

it reacts with glucose to give carbon dioxide, water molecules and potassium chloride: 3 KClO4 + C6H12O6 → 6 CO2 + 6 H2O + 3 KCl The conversion of solid...

sodium potassium pump, and are paired with water to thin the mucus of the airway lumen when the active Cystic Fibrosis Transport Receptor moves chloride ions...

membrane while another is cotransported in the opposite direction. In a symporter, two substrates are transported in the same direction across the membrane...

Thiazide diuretics reduce potassium concentration in blood through two indirect mechanisms: inhibition of sodium-chloride symporter at distal convoluted tubule...

The potassium (K+) uptake permease (KUP) family (TC# 2.A.72) is a member of the APC superfamily of secondary carriers. Proteins of the KUP/HAK/KT family...

Sodium/potassium/calcium exchanger 5 (NCKX5), also known as solute carrier family 24 member 5 (SLC24A5), is a protein that in humans is encoded by the...

act on the Na+-K+-2Cl− symporter (NKCC2) in the thick ascending limb of the loop of Henle to inhibit sodium, chloride and potassium reabsorption. This is...

permeable to ions. Ascending limb of loop of Henle Sodium (Na+), potassium (K+) and chloride (Cl−) ions are reabsorbed from the urine by secondary active...

Chlortalidone reduces reabsorption of sodium and chloride primarily through inhibition of the Na+/Cl− symporter in the apical membrane of distal convoluted...

membrane by Na+/K+-ATPases, and chloride ions pass by facilitated diffusion through basolateral chloride channels. Potassium, however, is able to diffuse...

restarted. The recommended formulation includes sodium chloride, sodium citrate, potassium chloride, and glucose. Glucose may be replaced by sucrose and...

acid:cation symporter (proton glutamate symporter) Monovalent cation/proton antiporter (Sodium/proton antiporter 1 NhaA) Neurotransmitter sodium symporter Ammonia...

nitrogen, creatinine, and basic electrolytes (including sodium, potassium, chloride, and bicarbonate). As the kidney is the most important organ in controlling...

hydrochlorothiazide act on the distal convoluted tubule and inhibit the sodium-chloride symporter leading to a retention of water in the urine, as water normally follows...

genes regulate the Sodium-chloride symporter (NCC) transporter, which is involved in controlling the levels of sodium and chloride in the body. Normally,...

dependent on both the concentration of potassium ion in the cytoplasm and the concentrations of sodium and chloride ions in the extracellular fluid. In order...

transport commonly uses types of carrier proteins, typically symporters and antiporters. Symporter proteins couple the transport of one molecule down its concentration...

another molecule up its electrochemical gradient. This is in contrast to symporters, which are another type of cotransporter that moves two or more ions in...

ascending limb is largely impermeable to water. Sodium (Na+), potassium (K+) and chloride (Cl−) ions are reabsorbed by active transport. The predominant...

The sodium/iodide cotransporter, also known as the sodium/iodide symporter (NIS), is a protein that in humans is encoded by the SLC5A5 gene. It is a transmembrane...

ions to harmless chloride, has also been proposed. Perchlorate is a potent competitive inhibitor of the thyroid sodium-iodide symporter. Thus, it has been...

Common side effects include dizziness, low blood pressure, low blood potassium, muscle cramps, and kidney problems. Other serious side effects may include...