• Thumbnail for Helicase
    Helicases are a class of enzymes thought to be vital to all organisms. Their main function is to unpack an organism's genetic material. Helicases are...
    56 KB (6,916 words) - 17:01, 27 August 2024
  • Thumbnail for DnaB helicase
    DnaB helicase is an enzyme in bacteria which opens the replication fork during DNA replication. Although the mechanism by which DnaB both couples ATP hydrolysis...
    6 KB (766 words) - 17:05, 27 August 2024
  • Thumbnail for Minichromosome maintenance
    The minichromosome maintenance protein complex (MCM) is a DNA helicase essential for genomic DNA replication. Eukaryotic MCM consists of six gene products...
    24 KB (3,042 words) - 22:16, 29 October 2022
  • Thumbnail for DNA replication
    DNA helicases for leading strands and lagging strands are loaded on the template DNAs, the helicases run along the DNAs into each other. The helicases remain...
    60 KB (7,286 words) - 08:26, 2 July 2024
  • A helicase–primase complex (also helicase-primase, Hel/Prim, H-P or H/P) is a complex of enzymes including DNA helicase and DNA primase. A helicase-primase...
    3 KB (331 words) - 17:05, 27 August 2024
  • Thumbnail for DEAD box
    but not all. Many organisms, including humans, contain DEAD-box (SF2) helicases, which are involved in RNA metabolism. DEAD box proteins were first brought...
    12 KB (1,436 words) - 16:39, 3 April 2024
  • Helicase-dependent amplification (HDA) is a method for in vitro DNA amplification (like the polymerase chain reaction) that takes place at a constant temperature...
    6 KB (741 words) - 21:52, 19 October 2024
  • RecQ helicase is a family of helicase enzymes initially found in Escherichia coli that has been shown to be important in genome maintenance. They function...
    17 KB (1,891 words) - 06:23, 24 September 2024
  • Thumbnail for Werner syndrome helicase
    helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. WRN is a member of the RecQ Helicase family...
    34 KB (4,157 words) - 13:23, 31 October 2024
  • Thumbnail for RNA Helicase A
    ATP-dependent RNA helicase A (RHA; also known as DHX9, LKP, and NDHI) is an enzyme that in humans is encoded by the DHX9 gene. DEAD/DEAH box helicases are proteins...
    14 KB (1,658 words) - 17:06, 27 August 2024
  • Chromodomain helicase DNA-binding (CHD) proteins is a subfamily of ATP-dependent chromatin remodeling complexes (remodelers). All remodelers fall under...
    6 KB (760 words) - 06:27, 24 September 2024
  • bacteria, primase binds to the DNA helicase forming a complex called the primosome. Primase is activated by the helicase where it then synthesizes a short...
    20 KB (2,371 words) - 23:07, 9 November 2024
  • Thumbnail for Eukaryotic DNA replication
    strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ahead of polymerases, forming a replication fork containing two single-stranded...
    119 KB (14,646 words) - 22:02, 3 July 2024
  • Thumbnail for LGP2
    ATP-dependent RNA helicase DHX58 also known as RIG-I-like receptor 3 (RLR-3) or RIG-I-like receptor LGP2 (RLR) is a RIG-I-like receptor dsRNA helicase enzyme that...
    9 KB (1,101 words) - 12:27, 13 August 2023
  • Thumbnail for PIF1 5'-to-3' DNA helicase
    PIF1 5'-to-3' DNA helicase is a protein that in humans is encoded by the PIF1 gene. This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing...
    4 KB (541 words) - 17:06, 27 August 2024
  • Thumbnail for Replisome
    Replisome (section Helicases)
    lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase III...
    32 KB (3,700 words) - 00:38, 1 January 2024
  • Thumbnail for HELLS
    Lymphoid-specific helicase (Lsh) is a member of the SNF2 helicase family of chromatin remodeling proteins that in humans is encoded by the HELLS gene...
    7 KB (746 words) - 16:58, 11 September 2024
  • RNA helicase database stored data about RNA helicases. The URL referenced in the article has been invalid since at least December 31st 2017. Helicase Jankowsky...
    2 KB (76 words) - 06:22, 24 September 2024
  • Thumbnail for Helicase, POLQ-like
    Helicase, POLQ-like, also known as Helicase Q (HELQ), HEL308 and Holliday junction migration protein, encoded by the gene HELQ1, is a DNA helicase found...
    14 KB (1,600 words) - 06:20, 24 September 2024
  • Thumbnail for DDX20
    DDX20 (redirect from DEAD-box helicase 20)
    Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded...
    14 KB (1,639 words) - 02:34, 16 July 2024
  • Thumbnail for Dicer
    Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the...
    26 KB (3,267 words) - 20:14, 27 September 2024
  • Thumbnail for DDX3X
    ATP-dependent RNA helicase DDX3X is an enzyme that in humans is encoded by the DDX3X gene. DEAD box proteins are putative RNA helicases characterized by...
    17 KB (1,788 words) - 09:39, 10 October 2024
  • Thumbnail for DHX8
    DHX8 (redirect from DEAH-box helicase 8)
    DEAH-box helicase 8, is a protein that in humans is encoded by the DHX8 gene. This protein is member of the DEAH box polypeptide family. The main characteristic...
    11 KB (1,311 words) - 22:09, 20 September 2024
  • Thumbnail for Twinkle (protein)
    Twinkle protein also known as twinkle mtDNA helicase is a mitochondrial protein that in humans is encoded by the TWNK gene (also known as C10orf2 or PEO1)...
    15 KB (1,860 words) - 16:07, 2 November 2024
  • Thumbnail for Origin of replication
    initiators (often with the help of co-loader proteins) deposit replicative helicases onto DNA, which subsequently drive the recruitment of additional replisome...
    113 KB (12,561 words) - 17:02, 14 May 2024
  • Thumbnail for Hoyeraal–Hreidarsson syndrome
    Lamm N, Dheekollu J, et al. (September 2013). "Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal–Hreidarsson syndrome". Proceedings...
    7 KB (570 words) - 01:49, 16 September 2024
  • Thumbnail for Pritelivir
    the drugs act through inhibition of the viral helicase primase complex, encoded by the UL5 (helicase), UL8 (scaffold protein) and UL52 (primase) genes...
    10 KB (997 words) - 16:34, 11 August 2024
  • Thumbnail for MDA5
    (melanoma differentiation-associated protein 5) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded by the IFIH1 gene in humans. MDA5 is part of the...
    18 KB (2,222 words) - 09:48, 7 July 2024
  • contains an Snf2 helicase domain that is responsible for the hydrolysis of ATP to adenosine diphosphate (ADP). CHD8 encodes a DNA helicase that functions...
    255 KB (27,437 words) - 20:40, 9 November 2024
  • Thumbnail for CHD8
    Chromodomain-helicase-DNA-binding protein 8 is an enzyme that in humans is encoded by the CHD8 gene. The gene CHD8 encodes the protein chromodomain helicase DNA...
    15 KB (1,606 words) - 09:02, 7 June 2024