In biochemistry, a kinase (/ˈkaɪneɪs, ˈkɪneɪs, -eɪz/) is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating...
34 KB (3,807 words) - 19:38, 18 August 2024
Mitogen-activated protein kinase kinase kinase kinase (MAP4K) is a family of proteins involved in cellular signal transduction. MAP4K1 (aka HPK1) MAP4K2...
880 bytes (84 words) - 18:46, 3 April 2021
Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme (EC 2.7.3.2) expressed by various tissues and...
16 KB (1,765 words) - 20:23, 29 July 2024
Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently...
11 KB (1,345 words) - 09:11, 2 January 2024
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as...
43 KB (5,251 words) - 10:44, 24 June 2024
In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
27 KB (2,665 words) - 17:03, 6 April 2024
unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not...
28 KB (3,078 words) - 07:46, 3 June 2024
protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which...
15 KB (1,635 words) - 23:25, 13 August 2024
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
46 KB (5,492 words) - 14:52, 20 August 2024
Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They...
9 KB (974 words) - 14:46, 22 June 2024
A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
14 KB (1,210 words) - 13:35, 14 June 2024
MTOR (redirect from Serine/threonine protein kinase mTOR)
a kinase that in humans is encoded by the MTOR gene. mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR...
119 KB (12,658 words) - 19:25, 19 September 2024
protein kinase kinase kinase 6 is a protein that in humans is encoded by the MAP3K6 gene. This gene encodes a serine/threonine protein kinase that forms...
4 KB (546 words) - 22:00, 3 December 2023
kinase] kinase (EC 2.7.11.3) is an enzyme that catalyzes the chemical reaction ATP + dephospho-{[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase}...
4 KB (411 words) - 13:47, 26 August 2023
transduction MAP kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase Dérijard B, et al. (1995). "Independent human MAP-kinase signal transduction...
3 KB (296 words) - 17:06, 14 September 2023
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
65 KB (7,149 words) - 04:45, 26 August 2024
Phosphatidylinositol 3-kinase-related kinases (PIKKs) are a family of Ser/Thr-protein kinases with sequence similarity to phosphatidylinositol-3 kinases (PI3Ks). The...
2 KB (106 words) - 09:29, 23 October 2022
Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to...
33 KB (4,042 words) - 02:51, 1 February 2024
In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
27 KB (2,716 words) - 12:30, 12 September 2024
Thymidylate kinase (EC 2.7.4.9; dTMP kinase) catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP)...
4 KB (350 words) - 06:28, 29 November 2023
Pyruvate kinase deficiency is an inherited metabolic disorder of the enzyme pyruvate kinase which affects the survival of red blood cells. Both autosomal...
14 KB (1,477 words) - 04:25, 9 August 2024
Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth...
32 KB (3,463 words) - 17:34, 20 November 2023
CAMK (redirect from Calcium/calmodulin-dependent protein kinase II)
or CCaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration...
8 KB (886 words) - 12:46, 31 January 2024
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,829 words) - 14:24, 17 June 2024
Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC 2.7.1.21. It can be found...
103 KB (11,263 words) - 21:37, 25 September 2024
NDR (nuclear dbf2-related) kinases, are an ancient and highly conserved subclass of AGC protein kinases that control diverse processes related to cell...
3 KB (422 words) - 19:38, 18 August 2024
A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, is a type of immune modulating medication, which inhibits the activity of one or more...
36 KB (3,044 words) - 22:30, 11 September 2024
Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck...
10 KB (1,215 words) - 14:38, 22 September 2024
Adenosine kinase (AdK; EC 2.7.1.20) is an enzyme that catalyzes the transfer of gamma-phosphate from Adenosine triphosphate (ATP) to adenosine (Ado) leading...
26 KB (3,178 words) - 04:45, 23 September 2024
RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. The mouse sarcoma virus 3611 contains...
5 KB (556 words) - 08:06, 3 June 2024