• Thumbnail for Ligand
    In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex. The...
    35 KB (3,307 words) - 14:02, 22 November 2024
  • Thumbnail for Ligand (biochemistry)
    In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from...
    29 KB (3,166 words) - 21:19, 21 August 2024
  • Thumbnail for Hill equation (biochemistry)
    equations that reflect the binding of ligands to macromolecules, as a function of the ligand concentration. A ligand is "a substance that forms a complex...
    30 KB (3,330 words) - 13:07, 4 October 2024
  • Thumbnail for Scorpionate ligand
    In coordination chemistry, a scorpionate ligand is a tridentate (three-donor-site) ligand that binds to a central atom in a fac manner. The most popular...
    11 KB (1,281 words) - 22:02, 19 July 2024
  • list of ligands ordered by ligand "strength", and a list of metal ions based on oxidation number, group and element. For a metal ion, the ligands modify...
    7 KB (700 words) - 05:25, 7 October 2024
  • Ligand field theory (LFT) describes the bonding, orbital arrangement, and other characteristics of coordination complexes. It represents an application...
    13 KB (1,581 words) - 05:06, 18 June 2024
  • Thumbnail for Fas ligand
    Fas ligand (FASL or CD95L) is a type-II transmembrane protein expressed on various types of cells, including cytotoxic T lymphocytes, monocytes, neutrophils...
    22 KB (2,547 words) - 08:19, 11 August 2024
  • Thumbnail for Trost ligand
    The Trost ligand is a diphosphine used in the palladium-catalyzed Trost asymmetric allylic alkylation. Other C2-symmetric ligands derived from trans-1...
    3 KB (79 words) - 18:46, 18 July 2023
  • Thumbnail for Ligand-gated ion channel
    Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open...
    29 KB (2,597 words) - 03:43, 7 April 2024
  • Thumbnail for Spectator ligand
    spectator ligand is a ligand that does not participate in chemical reactions of the complex. Instead, spectator ligands (vs "actor ligands") occupy coordination...
    2 KB (233 words) - 15:09, 29 May 2024
  • coordination chemistry, ligand isomerism is a type of structural isomerism in coordination complexes which arises from the presence of ligands which can adopt...
    1 KB (77 words) - 20:49, 23 August 2024
  • Thumbnail for Bridging ligand
    coordination chemistry, a bridging ligand is a ligand that connects two or more atoms, usually metal ions. The ligand may be atomic or polyatomic. Virtually...
    8 KB (844 words) - 15:08, 6 July 2023
  • ligand refers to a ligand that accepts two electrons from the metal center. This is in contrast to X-type ligands, which form a bond with the ligand and...
    9 KB (1,102 words) - 15:15, 23 February 2023
  • Chelation (redirect from Chelating ligand)
    coordinate bonds between a polydentate (multiple bonded) ligand and a single central metal atom. These ligands are called chelants, chelators, chelating agents...
    25 KB (2,842 words) - 18:07, 19 November 2024
  • Thumbnail for Ligand Pharmaceuticals
    Ligand Pharmaceuticals Incorporated is a biopharmaceutical company located in San Diego, California. Founded in 1987 as Progenix Inc., the company went...
    14 KB (1,245 words) - 20:45, 24 October 2024
  • Thumbnail for Tridentate ligand
    A tridentate ligand (or terdentate ligand) is a ligand that has three atoms that can function as donor atoms in a coordination complex. Well-known tridentate...
    4 KB (201 words) - 12:52, 16 October 2023
  • Ligand efficiency is a measurement of the binding energy per atom of a ligand to its binding partner, such as a receptor or enzyme. Ligand efficiency is...
    5 KB (576 words) - 14:23, 16 October 2024
  • Thumbnail for Receptor (biochemistry)
    sends the signal onward, amplification increases the effect of a single ligand, and integration allows the signal to be incorporated into another biochemical...
    26 KB (2,672 words) - 14:14, 22 July 2024
  • Thumbnail for Transition metal pincer complex
    pincer complex is a type of coordination complex with a pincer ligand. Pincer ligands are chelating agents that binds tightly to three adjacent coplanar...
    15 KB (1,768 words) - 23:49, 20 December 2023
  • Thumbnail for Protein–ligand complex
    A protein–ligand complex is a complex of a protein bound with a ligand that is formed following molecular recognition between proteins that interact with...
    11 KB (1,297 words) - 07:08, 20 January 2024
  • breaking assumptions made of relative metal and ligand orbital energies, requiring the use of inverted ligand field theory (ILFT) to better describe bonding...
    17 KB (1,998 words) - 17:53, 20 January 2024
  • Thumbnail for Hexadentate ligand
    hexadentate ligand in coordination chemistry is a ligand that combines with a central metal atom with six bonds. One example of a hexadentate ligand that can...
    2 KB (234 words) - 23:35, 21 July 2023
  • Thumbnail for Salen ligand
    Salen refers to a tetradentate C2-symmetric ligand synthesized from salicylaldehyde (sal) and ethylenediamine (en). It may also refer to a class of compounds...
    4 KB (274 words) - 13:03, 21 October 2024
  • Thumbnail for Denticity
    Denticity (redirect from Monodentate ligand)
    groups in a given ligand that bind to the central metal atom in a coordination complex. In many cases, only one atom in the ligand binds to the metal...
    5 KB (669 words) - 11:37, 1 October 2024
  • Ligand may refer to: Ligand, an atom, ion, or functional group that donates one or more of its electrons through a coordinate covalent bond to one or...
    361 bytes (82 words) - 20:04, 9 January 2019
  • Thumbnail for Drug design
    Drug design (redirect from Ligand design)
    therapeutics have also been developed. The phrase "drug design" is similar to ligand design (i.e., design of a molecule that will bind tightly to its target)...
    44 KB (5,022 words) - 08:47, 12 October 2024
  • In chemistry, tetradentate ligands are ligands that bind four donor atoms to a central atom to form a coordination complex. This number of donor atoms...
    21 KB (1,858 words) - 07:47, 8 September 2024
  • LigandScout is computer software that allows creating three-dimensional (3D) pharmacophore models from structural data of macromolecule–ligand complexes...
    5 KB (374 words) - 07:36, 3 October 2022
  • Thumbnail for Docking (molecular)
    which predicts the preferred orientation of one molecule to a second when a ligand and a target are bound to each other to form a stable complex. Knowledge...
    33 KB (3,935 words) - 01:22, 28 October 2024
  • Protein–ligand docking is a molecular modelling technique. The goal of protein–ligand docking is to predict the position and orientation of a ligand (a small...
    11 KB (1,453 words) - 07:19, 26 October 2023