Miglustat, sold under the brand name Zavesca among others, is a medication used to treat type I Gaucher disease and Pompe disease. It was approved for...
21 KB (1,684 words) - 05:57, 27 January 2024
Velaglucerase (approved in 2010) Taliglucerase alfa (Elelyso) (approved in 2012) Miglustat is a small molecule, orally available drug that was first approved for...
30 KB (3,303 words) - 02:36, 22 May 2024
has been tried for type B. In January 2009, Actelion announced the drug miglustat (Zavesca) had been approved in the European Union for the treatment of...
27 KB (3,118 words) - 04:33, 17 June 2024
1% of patients. No clinical interaction studies have been conducted. Miglustat appears to increase the clearance of imiglucerase by 70%, resulting in...
7 KB (552 words) - 13:38, 13 November 2023
alfa, sold under the brand name Pombiliti, and used in combination with miglustat, is a medication used for the treatment of glycogen storage disease type...
12 KB (908 words) - 12:29, 14 June 2024
metabolized and is excreted by the kidneys. Alpha-glucosidase inhibitor Miglustat Voglibose "Migliotl: MedlinePlus Drug Information". MedlinePlus. National...
4 KB (183 words) - 00:50, 5 January 2023
Glycomimetic (section Miglustat)
a drug against type 2 diabetes. Miglustat is an iminosugar in which the ring oxygen is replaced by nitrogen. Miglustat a drug used to treat some rare lysosomal...
3 KB (464 words) - 19:17, 9 December 2020
C enzyme, are still in development as potential male contraceptives. Miglustat (Zavesca or NB-DNJ) is a drug approved for treatment of several rare lipid...
143 KB (15,148 words) - 03:51, 22 July 2024
multiple sclerosis, and migraine. One drug that has been tried is Miglustat. Miglustat is a glucosylceramide synthase inhibitor, which inhibits the synthesis...
46 KB (5,123 words) - 16:12, 16 May 2024
glucocerebroside. It is classified under EC 2.4.1.80. It is inhibited by miglustat and eliglustat, both drugs developed for the treatment of Gaucher disease...
1 KB (118 words) - 18:34, 23 January 2024
Another metabolic therapy under investigation for Tay–Sachs disease uses miglustat. This drug is a reversible inhibitor of the enzyme glucosylceramide synthase...
58 KB (6,401 words) - 03:55, 22 June 2024
two-component therapy of Pombiliti (cipaglucosidase alfa-atga) and Opfolda (miglustat) 65 mg capsules for adults living with late-onset Pompe disease weighing...
36 KB (4,307 words) - 02:03, 18 June 2024
treat desmoid tumors Pombiliti To treat late-onset Pompe disease with miglustat Rivfloza To lower urinary oxalate levels in primary hyperoxaluria type...
34 KB (180 words) - 22:09, 8 April 2024
medicines, N-hydroxyethyl-DNJ (miglitol) for diabetes and N-butyl-DNJ (miglustat) for Gaucher's disease. Anti-cancer and anti-viral activity was subsequently...
3 KB (405 words) - 15:37, 7 September 2023
receptor antagonist, see also: Endothelin receptor antagonist. Zavesca (miglustat): is currently the only approved oral treatment for patients with mild...
25 KB (2,589 words) - 03:31, 21 May 2024
February 2018 the FDA accepted it and promised a response by August 2018. Miglustat, a drug for the treatment of Gaucher disease, with a similar structure...
17 KB (1,464 words) - 07:10, 1 July 2024
effective in treating lysosomal diseases. She managed to get the drug (Miglustat) approved by the European Medicines Agency and Food and Drug Administration...
6 KB (660 words) - 04:01, 7 February 2024
Sodium phenylbutyrate A16AX04 Nitisinone A16AX05 Zinc acetate A16AX06 Miglustat A16AX07 Sapropterin A16AX08 Teduglutide A16AX09 Glycerol phenylbutyrate...
3 KB (358 words) - 02:46, 18 December 2023
include treatment with the drug OGT 918 (Zavesca). Gaucher's disease. Miglustat and eliglustat are substrate reduction therapies for Gaucher's disease...
4 KB (528 words) - 18:42, 21 November 2023
β-glucocerebrosidase for enzyme replacement therapy of Gaucher's disease Miglustat, another orphan drug for the treatment of Gaucher's disease with a different...
5 KB (416 words) - 14:05, 10 May 2023