Monoamine oxidase B (MAO-B) is an enzyme that in humans is encoded by the MAOB gene. The protein encoded by this gene belongs to the flavin monoamine...
37 KB (4,431 words) - 19:04, 30 September 2024
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...
37 KB (4,010 words) - 17:19, 13 October 2024
Monoamine oxidases (MAO) (EC 1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group...
38 KB (4,085 words) - 19:06, 30 September 2024
Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring...
40 KB (4,635 words) - 13:34, 21 September 2024
Rasagiline (category Monoamine oxidase inhibitors)
enzyme monoamine oxidase (MAO) and hence is a monoamine oxidase inhibitor (MAOI). More specifically, it is a selective inhibitor of monoamine oxidase B (MAO-B)...
90 KB (8,896 words) - 00:46, 20 October 2024
Phenethylamine (redirect from B-phenylethylamine)
a significant amount is metabolized in the small intestine by monoamine oxidase B (MAO-B) and then aldehyde dehydrogenase (ALDH), which converts it to...
46 KB (4,510 words) - 12:55, 16 October 2024
Harmala alkaloid (category Monoamine oxidase inhibitors)
Harmala alkaloids are several alkaloids that act as monoamine oxidase inhibitors (MAOIs). These alkaloids are found in the seeds of Peganum harmala (also...
14 KB (1,526 words) - 03:35, 8 September 2024
a monoamine oxidase (MAO) inhibitor. It is a selective inhibitor of monoamine oxidase B (MAO-B) at lower doses but additionally inhibits monoamine oxidase...
137 KB (13,992 words) - 23:53, 18 October 2024
Selegiline (category Monoamine oxidase inhibitors)
of monoamine oxidase B (MAO-B), increasing brain levels of dopamine. At higher doses, it loses its specificity for MAO-B and also inhibits monoamine oxidase...
208 KB (20,184 words) - 23:53, 18 October 2024
noradrenergic and specific serotonergic antidepressants (NaSSAs). Monoamine oxidase inhibitors include Isocarboxazid (Marplan) Phenelzine (Nardil) Tranylcypromine...
18 KB (1,486 words) - 18:57, 19 October 2024
Hydrazine (antidepressant) (redirect from Hydrazine (monoamine oxidase inhibitor))
hydrazine antidepressants are a group of non-selective, irreversible monoamine oxidase inhibitors (MAOIs) which were discovered and initially marketed in...
2 KB (162 words) - 17:14, 22 September 2024
Brunner syndrome (redirect from Monoamine oxidase A (MAOA) deficiency)
diarrhea Brunner syndrome is caused by a monoamine oxidase A (MAOA) deficiency, which leads to an excess of monoamines in the brain, such as serotonin, dopamine...
8 KB (845 words) - 19:42, 27 September 2024
SU-11739 (category Monoamine oxidase inhibitors)
experimental monoamine oxidase inhibitor (MAOI) that was never marketed. It is a dual or non-selective irreversible monoamine oxidase A (MAO-A) and monoamine oxidase...
7 KB (534 words) - 07:05, 1 October 2024
Monoamine reuptake inhibitor Monoamine receptor Monoamine oxidase Monoamine transporter Monoamine Hypothesis Biogenic amine Trace amine Monoamine nuclei...
7 KB (1,409 words) - 21:17, 11 March 2024
Metralindole (category Monoamine oxidase inhibitors)
Metralindole (Inkazan) is a reversible inhibitor of monoamine oxidase A (RIMA) which was investigated in Russia as a potential antidepressant. It is structurally...
2 KB (77 words) - 18:46, 18 October 2024
transformations in this pathway include putrescine acetyltransferase (PAT), monoamine oxidase B (MAO-B), aldehyde dehydrogenase (ALDH), and an unknown deacetylase enzyme...
4 KB (297 words) - 20:35, 19 October 2024
9-Methyl-β-carboline (category Monoamine oxidase inhibitors)
model of Parkinsonism. 9-Me-BC is a known inhibitor of monoamine oxidase A and monoamine oxidase B, and has been proposed for further investigation in the...
7 KB (553 words) - 19:38, 8 September 2024
Desmethylselegiline (category Monoamine oxidase inhibitors)
selegiline, DMS is a monoamine oxidase inhibitor (MAOI); specifically, it is a selective and irreversible inhibitor of monoamine oxidase B (MAO-B). In addition...
19 KB (1,485 words) - 00:57, 20 August 2024
Parkinson's disease (section MAO-B inhibitors)
IF, Gåsemyr J, Natvig B, Klemp M (September 2018). "A multiple treatment comparison meta-analysis of monoamine oxidase type B inhibitors for Parkinson's...
175 KB (19,045 words) - 14:46, 20 October 2024
neurochemistry and neuropharmacology. He is the discoverer of both monoamine oxidase (MAO) B inhibitors l-deprenyl (Selegiline) and rasagiline (Azilect) as...
17 KB (1,821 words) - 17:40, 12 September 2024
serotonin inactivation. Monoamine oxidase A (MAO-A) has about 120-fold higher affinity for serotonin than monoamine oxidase B (MAO-B). In relation to this...
7 KB (621 words) - 00:18, 9 September 2024
diamine oxidase (DAO) and aminobutyraldehyde dehydrogenase (ABALDH) (e.g., ALDH9A1). Putrescine is converted into ABAL via monoamine oxidase B (MAO-B). However...
6 KB (552 words) - 22:02, 8 October 2024
Pargyline (category Monoamine oxidase inhibitors)
Pargyline, sold under the brand name Eutonyl among others, is a monoamine oxidase inhibitor (MAOI) medication which has been used to treat hypertension...
43 KB (4,057 words) - 00:51, 20 October 2024
Safinamide (category Monoamine oxidase inhibitors)
episodes; it has multiple modes of action, including the inhibition of monoamine oxidase B. It was approved in the European Union in February 2015, in the United...
20 KB (1,727 words) - 03:02, 26 September 2024
alcohol withdrawal. It should be avoided in individuals who are taking monoamine oxidase inhibitors (MAOIs). The label recommends that caution should be exercised...
135 KB (12,405 words) - 17:38, 18 October 2024
SNRIs, TCAs, and MAOIs, which act mainly by increasing the levels of the monoamine neurotransmitters serotonin and/or norepinephrine. Among TCAs, trimipramine...
3 KB (290 words) - 00:06, 11 March 2024
by-product. Benzylamine is degraded biologically by the action of the monoamine oxidase B enzyme, resulting in benzaldehyde. Benzylamine is used as a masked...
15 KB (1,193 words) - 02:21, 9 September 2024
Antidepressant (section Monoamine oxidase inhibitors)
contain three rings of atoms. Monoamine oxidase inhibitors (MAOIs) are chemicals that inhibit the activity of the monoamine oxidase enzyme family. They have...
197 KB (20,780 words) - 20:54, 10 October 2024
syndrome. Taking monoamine oxidase inhibitors (MAOIs) in combination with SSRIs can be fatal, since MAOIs disrupt monoamine oxidase, an enzyme which is...
142 KB (15,105 words) - 07:45, 29 September 2024
between ketamine and the monoamine oxidase inhibitor (MAOI) tranylcypromine, which is of importance as the combination of a monoamine reuptake inhibitor with...
116 KB (11,202 words) - 06:03, 17 October 2024