Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical...
74 KB (8,396 words) - 00:09, 26 April 2024
contributed an understanding of protein folding and structure mediated by hydrophobic interactions. The first protein to have its amino acid chain sequenced...
102 KB (11,386 words) - 22:54, 1 October 2024
Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions...
25 KB (2,915 words) - 08:44, 9 May 2024
Protein–protein interactions can be designed using protein design algorithms because the principles that rule protein stability also rule protein–protein binding...
63 KB (7,685 words) - 00:41, 12 October 2024
to investigate protein–protein interactions which are the physical contacts of high specificity established between two or more protein molecules involving...
35 KB (4,515 words) - 07:57, 6 August 2024
affects a large portion of proteins. Even if a protein is not phosphorylated itself, its interactions with other proteins may be regulated by phosphorylation...
67 KB (7,955 words) - 20:50, 29 July 2024
chain. Protein complexes are a form of quaternary structure. Proteins in a protein complex are linked by non-covalent protein–protein interactions. These...
25 KB (2,841 words) - 17:04, 19 May 2024
website. Biology portal Protein design Protein function prediction Protein–protein interaction prediction Gene prediction Protein structure prediction software...
71 KB (9,030 words) - 16:26, 15 October 2024
native structure of a protein. Tertiary structure of a protein involves a single polypeptide chain; however, additional interactions of folded polypeptide...
76 KB (8,675 words) - 03:46, 1 October 2024
non-covalent interactions, such as hydrogen bonding, ionic interactions, Van der Waals forces, and hydrophobic packing. To understand the functions of proteins at...
37 KB (4,204 words) - 19:21, 25 September 2024
activator like effectors. Structural proteins that bind DNA are well-understood examples of non-specific DNA-protein interactions. Within chromosomes, DNA is held...
22 KB (2,633 words) - 17:35, 18 September 2024
Protein–protein interaction screening refers to the identification of Protein–protein interaction with high-throughput screening methods such as computer-...
6 KB (726 words) - 13:48, 18 November 2021
between a protein and a functional, proteinaceous unit was difficult to elucidate. More recently, people refer to protein–protein interaction when discussing...
21 KB (2,342 words) - 16:59, 19 May 2024
of skin penetration. Protein A can inflame lung tissue by binding to tumor necrosis factor 1 (TNFR-1) receptors. This interaction has been shown to play...
17 KB (1,860 words) - 10:05, 20 May 2024
Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation...
40 KB (4,342 words) - 18:58, 2 April 2024
biology research in order to track protein interactions in real time. The first fluorescent tag, green fluorescent protein (GFP), was isolated from Aequorea...
19 KB (2,305 words) - 05:22, 15 May 2024
G-protein activation. However, the possibility for interaction does allow for G-protein-independent signaling to occur. There are three main G-protein-mediated...
82 KB (9,384 words) - 16:34, 5 September 2024
assembly of multi-protein complexes by increasing the probability of any appropriate protein–protein interactions. Peripheral membrane proteins may interact...
55 KB (4,414 words) - 20:08, 7 October 2024
In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest...
71 KB (8,443 words) - 19:00, 15 August 2024
Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside...
53 KB (6,404 words) - 17:09, 30 September 2024
chromosome stability, its interaction with the cellular transcriptome, its interaction with other cytoskeletal or synaptic proteins, its involvement in myelination...
55 KB (6,241 words) - 00:08, 3 October 2024
Protein metabolism denotes the various biochemical processes responsible for the synthesis of proteins and amino acids (anabolism), and the breakdown of...
27 KB (2,828 words) - 13:35, 3 August 2024
A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases...
15 KB (1,635 words) - 23:25, 13 August 2024
precipitate a protein. Addition of a neutral salt, such as ammonium sulfate, compresses the solvation layer and increases protein–protein interactions. As the...
15 KB (2,076 words) - 04:30, 25 August 2024
enhance signaling specificity by preventing unnecessary interactions between signaling proteins, and enhance signaling efficiency by increasing the proximity...
25 KB (2,159 words) - 11:01, 3 August 2024
outwards, allowing dipole–dipole interactions with the solvent, which explains the molecule's solubility. Globular proteins are only marginally stable because...
6 KB (746 words) - 12:06, 14 October 2024
In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently...
6 KB (653 words) - 16:09, 6 October 2024
Motor proteins are a class of molecular motors that can move along the cytoskeleton of cells. They convert chemical energy into mechanical work by the...
13 KB (1,538 words) - 23:48, 17 April 2024
or whole organisms. Protein purification is vital for the specification of the function, structure and interactions of the protein of interest. The purification...
30 KB (3,919 words) - 03:34, 22 June 2024
Membrane proteins are common proteins that are part of, or interact with, biological membranes. Membrane proteins fall into several broad categories depending...
18 KB (1,819 words) - 23:55, 25 April 2024