biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms...
71 KB (8,443 words) - 19:00, 15 August 2024
2) domain is a structurally conserved protein domain contained within the Src oncoprotein and in many other intracellular signal-transducing proteins. SH2...
13 KB (1,341 words) - 13:40, 20 November 2024
This may use either whole proteins or protein domains, especially in multi-domain proteins. Protein domains allow protein classification by a combination...
103 KB (11,472 words) - 16:37, 31 October 2024
Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers – specifically polypeptides – formed...
37 KB (4,208 words) - 04:07, 27 October 2024
Zinc finger (redirect from Zinc finger protein domain)
protein followed soon thereafter by the Krüppel factor in Drosophila. It often appears as a metal-binding domain in multi-domain proteins. Proteins that...
42 KB (4,879 words) - 13:27, 9 October 2024
Solenoid protein domains are a highly modular type of protein domain. They consist of a chain of nearly identical folds, often simply called tandem repeats...
9 KB (1,081 words) - 03:24, 12 December 2020
The SRC Homology 3 Domain (or SH3 domain) is a small protein domain of about 60 amino acid residues. Initially, SH3 was described as a conserved sequence...
8 KB (933 words) - 12:56, 10 September 2024
within many protein structural domains, resulting in an activation of their biological activity. Additionally, the positioning of many proteins are localized...
55 KB (4,414 words) - 20:08, 7 October 2024
The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases are a group...
17 KB (1,566 words) - 18:56, 22 September 2024
A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded...
19 KB (2,167 words) - 16:54, 24 September 2024
(UBA) domains are protein domains that non-covalently interact with ubiquitin through protein-protein interactions. Ubiquitin is a small protein that is...
8 KB (787 words) - 13:58, 10 September 2024
single polypeptide chain "backbone" with one or more protein secondary structures, the protein domains. Amino acid side chains and the backbone may interact...
15 KB (1,603 words) - 16:54, 15 June 2024
Magnetic domain (physics), a region within a magnetic material which has uniform magnetization Protein domain (biology), a part of a protein that can...
6 KB (843 words) - 09:46, 9 August 2024
domain is a common structural domain of 80-90 amino-acids found in the signaling proteins of bacteria, yeast, plants, viruses and animals. Proteins containing...
34 KB (3,565 words) - 02:04, 3 December 2023
the protein domain Stirrup is a domain, found only in found in the domain, archaea. The Stirrup protein domain is found in prokaryotic protein ribonucleotide...
2 KB (176 words) - 17:24, 29 August 2024
A protein family is a group of evolutionarily related proteins. In many cases, a protein family has a corresponding gene family, in which each gene encodes...
15 KB (1,571 words) - 13:41, 4 September 2024
A transmembrane domain (TMD) is a membrane-spanning protein domain. TMDs may consist of one or several alpha-helices or a transmembrane beta barrel. Because...
8 KB (1,006 words) - 02:00, 4 November 2024
A Per-Arnt-Sim (PAS) domain is a protein domain found in all kingdoms of life. Generally, the PAS domain acts as a molecular sensor, whereby small molecules...
17 KB (1,777 words) - 06:08, 5 October 2024
intracellular heterotrimeric G protein complex by protein domain dynamics. The Gs alpha subunit of the stimulated G protein complex exchanges GDP for GTP...
27 KB (2,665 words) - 17:03, 6 April 2024
In molecular biology, the protein domain YTH refers to a member of the YTH family that has been shown to selectively remove transcripts of meiosis-specific...
7 KB (764 words) - 03:56, 11 September 2024
GTPase (section G domain GTPases)
and hydrolysis takes place in the highly conserved P-loop "G domain", a protein domain common to many GTPases. GTPases function as molecular switches...
20 KB (2,306 words) - 18:17, 15 July 2024
Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of...
71 KB (9,035 words) - 04:09, 27 October 2024
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors...
82 KB (9,384 words) - 16:34, 5 September 2024
the regulation of gene expression. The AAA proteins contain two domains, an N-terminal alpha/beta domain that binds and hydrolyzes nucleotides (a Rossmann...
12 KB (1,352 words) - 03:31, 10 November 2024
molecular biology, the SAG1 protein domain is an example of a group of glycosylphosphatidylinositol (GPI)-linked proteins named SRSs (SAG1 related sequence)...
4 KB (359 words) - 03:49, 29 November 2023
The WWE domains occur in two functional classes of proteins, namely those associated with ubiquitination and those associated with poly-ADP ribosylation...
3 KB (276 words) - 20:56, 27 June 2022
peptides and therefore contain all functional domains of the original proteins. However, other fusion proteins, especially those that occur naturally, combine...
19 KB (2,305 words) - 05:22, 15 May 2024
In molecular biology, the WAC domain is a protein domain found on the N-terminus of WSTF protein. Its function is still unknown, but putatively thought...
3 KB (415 words) - 20:55, 27 June 2022
feature of many spiral galaxies Bar (unit), a unit of pressure BAR domain, a protein domain Bar stock, of metal Sandbar Bar (computer science), a placeholder...
3 KB (444 words) - 17:55, 9 October 2024
Pleckstrin homology domain (PH domain) or (PHIP) is a protein domain of approximately 120 amino acids that occurs in a wide range of proteins involved in intracellular...
14 KB (1,434 words) - 18:03, 6 October 2024