• Trk receptors are a family of tyrosine kinases that regulates synaptic strength and plasticity in the mammalian nervous system. Trk receptors affect neuronal...
    27 KB (3,122 words) - 21:45, 8 July 2024
  • Thumbnail for Tropomyosin receptor kinase B
    Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type...
    40 KB (4,319 words) - 00:58, 9 June 2024
  • Thumbnail for Tropomyosin receptor kinase A
    Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
    27 KB (3,264 words) - 05:43, 13 April 2024
  • Thumbnail for Tropomyosin receptor kinase C
    Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase...
    32 KB (3,936 words) - 03:00, 29 January 2024
  • Thumbnail for Brain-derived neurotrophic factor
    Brain-derived neurotrophic factor (category TrkB agonists)
    activates the TrkB tyrosine kinase receptor. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system expressing TrkB, helping...
    46 KB (5,344 words) - 04:27, 29 July 2024
  • Thumbnail for Nerve growth factor
    TrkA receptor facilitates receptor dimerization and tyrosine residue phosphorylation of the cytoplasmic tail by adjacent Trk receptors. Trk receptor phosphorylation...
    24 KB (2,872 words) - 06:27, 22 July 2024
  • Indonesia Potassium transport proteins (Trk), a constituent of the protein family bacterial potassium transporter Trk receptor, a family of tyrosine kinases that...
    633 bytes (116 words) - 17:00, 18 April 2024
  • neurotrophic factor receptors are the p75 and the "Trk" families of Tyrosine kinases receptors. p75 is a low affinity neurotrophin receptor, to which all neurotrophins...
    5 KB (670 words) - 17:28, 23 January 2021
  • Thumbnail for Neurotrophin
    stimulate, given its ability to activate two of the receptor tyrosine kinase neurotrophin receptors (TrkC and TrkB). Mice born without the ability to make NT-3...
    27 KB (3,071 words) - 04:54, 3 June 2024
  • Thumbnail for Neurotrophin-3
    Neurotrophin-3 (category TrkB agonists)
    stimulate, given its ability to activate two of the receptor tyrosine kinase neurotrophin receptors (TrkC and TrkB). Mice born without the ability to make NT-3...
    14 KB (1,816 words) - 04:39, 31 October 2023
  • Thumbnail for Low-affinity nerve growth factor receptor
    TrkA. p75NTR activation of NF-kB, which promotes survival, is unaffected by NGF binding to TrkA. p75NTR functions in a complex with Nogo-66 receptor (NgR1)...
    37 KB (4,235 words) - 13:48, 29 June 2024
  • Thumbnail for Receptor tyrosine kinase
    Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • Thumbnail for VEGF receptor
    VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
    8 KB (755 words) - 18:51, 2 November 2023
  • Thumbnail for Adenosine
    Adenosine (category Adenosine receptor agonists)
    adenosine agonists can activate Trk receptor phosphorylation through a mechanism that requires the adenosine A2A receptor. Adenosine has been shown to promote...
    32 KB (3,346 words) - 12:19, 4 July 2024
  • Thumbnail for Epidermal growth factor receptor
    The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth...
    60 KB (6,879 words) - 14:26, 16 July 2024
  • Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They...
    9 KB (974 words) - 14:46, 22 June 2024
  • Thumbnail for HER2
    HER2 (redirect from ErbB-2 receptor)
    Receptor tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated...
    43 KB (4,651 words) - 13:41, 27 July 2024
  • Thumbnail for Charcot–Marie–Tooth disease
    interacting with the extracellular region of tropomyosin receptor kinase, or Trk, receptors. Trk receptors are crucial to the survival and development of sensory...
    40 KB (4,422 words) - 12:21, 19 July 2024
  • The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
    8 KB (827 words) - 22:08, 3 December 2023
  • Thumbnail for Angiotensin
    for angiotensin receptors, although their exact role is still unclear. The action of AII itself is targeted by angiotensin II receptor antagonists, which...
    28 KB (3,125 words) - 13:46, 21 July 2024
  • A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic...
    6 KB (625 words) - 00:59, 6 June 2024
  • Thumbnail for Tyrosine kinase
    factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor, and colony-stimulating factor-1 receptor (Burstein...
    43 KB (5,251 words) - 10:44, 24 June 2024
  • Thumbnail for Bruton's tyrosine kinase
    development as it is required for transmitting signals from the pre-B cell receptor that forms after successful immunoglobulin heavy chain rearrangement. It...
    22 KB (2,389 words) - 06:43, 22 April 2024
  • Thumbnail for Insulin receptor
    The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase...
    31 KB (3,785 words) - 16:28, 25 May 2024
  • Thumbnail for Nalfurafine
    Nalfurafine (redirect from TRK-820)
    Nalfurafine (INN, USAN) (brand name Remitch; former developmental code names TRK-820, AC-820, MT-9938) is an antipruritic (anti-itch drug) that is marketed...
    16 KB (1,282 words) - 21:59, 16 May 2024
  • Thumbnail for KIT (gene)
    KIT (gene) (redirect from C-kit receptor)
    Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation...
    35 KB (4,117 words) - 14:30, 7 July 2024
  • family of proteins contains four receptor tyrosine kinases, structurally related to the epidermal growth factor receptor (EGFR), its first discovered member...
    24 KB (2,736 words) - 00:12, 28 November 2023
  • Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck...
    10 KB (1,215 words) - 03:15, 19 April 2024
  • Thumbnail for GRB2
    1998). "Identification and characterization of novel substrates of Trk receptors in developing neurons". Neuron. 21 (5): 1017–29. doi:10.1016/s0896-6273(00)80620-0...
    82 KB (9,365 words) - 15:39, 31 March 2024
  • Thumbnail for Platelet-derived growth factor receptor
    Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF)...
    13 KB (1,563 words) - 09:00, 13 March 2024