• Thumbnail for Tumor necrosis factor
    are inert. When TNF binds to its receptors, tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2), a pathway of signals is...
    49 KB (6,227 words) - 14:52, 18 November 2024
  • Thumbnail for Tumor necrosis factor superfamily
    The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers...
    8 KB (316 words) - 13:53, 10 September 2024
  • Thumbnail for TNF receptor superfamily
    The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis...
    8 KB (501 words) - 13:55, 10 September 2024
  • Thumbnail for Tumor necrosis factor receptor 1
    Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane...
    20 KB (2,146 words) - 16:24, 21 August 2024
  • pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response. TNF is involved...
    33 KB (3,686 words) - 07:30, 20 May 2024
  • Thumbnail for Tumor necrosis factor receptor 2
    Tumor necrosis factor receptor 2 (TNFR2), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) and CD120b, is one of two membrane...
    12 KB (1,387 words) - 13:47, 4 September 2024
  • Thumbnail for Lymphotoxin alpha
    Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA gene. Belonging to the...
    24 KB (2,809 words) - 11:12, 20 August 2024
  • Thumbnail for Transforming growth factor beta
    Hussain; Shawana, Summayya (2020). "Dysregulated epidermal growth factor and tumor growth factor-beta receptor signaling through GFAP-ACTA2 protein interaction...
    67 KB (8,184 words) - 20:48, 31 October 2024
  • Lymphotoxin is a member of the tumor necrosis factor (TNF) superfamily of cytokines, whose members are responsible for regulating the growth and function...
    12 KB (1,459 words) - 03:14, 30 October 2022
  • Thumbnail for Fas receptor
    antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans...
    23 KB (2,675 words) - 19:25, 12 November 2023
  • Thumbnail for TNF receptor associated periodic syndrome
    syndrome associated with mutations in a receptor for the molecule tumor necrosis factor (TNF) that is inheritable in an autosomal dominant manner. Individuals...
    10 KB (745 words) - 14:46, 24 August 2024
  • Thumbnail for TRADD
    Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein that in humans is encoded by the TRADD gene. TRADD is an adaptor protein...
    16 KB (1,974 words) - 06:12, 25 December 2023
  • Thumbnail for B-cell activating factor
    B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans...
    25 KB (3,095 words) - 14:05, 12 March 2024
  • Thumbnail for RANKL
    Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
    28 KB (3,305 words) - 13:29, 8 November 2024
  • Thumbnail for ADAM17
    disintegrin and metalloprotease 17 (ADAM17), also called TACE (tumor necrosis factor-α-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM...
    21 KB (2,494 words) - 10:51, 5 November 2024
  • Thumbnail for CD137
    CD137, a member of the tumor necrosis factor (TNF) receptor family, is a type 1 transmembrane protein, expressed on surfaces of leukocytes and non-immune...
    20 KB (2,338 words) - 17:17, 19 November 2024
  • lipopolysaccharide is thought to increase lymphocyte activity and boosts tumor necrosis factor (TNF). Tsung and Norton in Surgical Oncology reported that the active...
    21 KB (2,297 words) - 17:26, 2 November 2024
  • Thumbnail for Inflammaging
    by the inflammasome to induce the mature, active form of IL-1B. Tumor necrosis factor-alpha (TNF-alpha) is an inflammatory cytokine produced upon acute...
    26 KB (3,020 words) - 17:03, 14 May 2024
  • two members of the tumor necrosis factor receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2)....
    4 KB (337 words) - 01:41, 3 December 2023
  • CD40. Tumor necrosis factors Inoue J, Ishida T, Tsukamoto N, Kobayashi N, Naito A, Azuma S, Yamamoto T (January 2000). "Tumor necrosis factor receptor-associated...
    1 KB (136 words) - 07:30, 11 December 2020
  • Thumbnail for CD30
    superfamily member 8), is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker. This receptor is expressed by activated, but...
    13 KB (1,665 words) - 07:13, 15 October 2024
  • Thumbnail for Psoriasis
    psoriasis. These genes are on the pathway that upregulate tumor necrosis factor-α and nuclear factor κB, two genes involved in inflammation. The first gene...
    116 KB (13,061 words) - 15:20, 6 November 2024
  • Thumbnail for APRIL (protein)
    A proliferation-inducing ligand (APRIL), also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily...
    12 KB (1,367 words) - 05:51, 22 August 2024
  • for blocking TNFα activation of the tumor necrosis factor receptor 1 (TNFR1) but not of the tumor necrosis factor receptor 2 (TNFR2). Whereas the non-selective...
    5 KB (305 words) - 05:22, 23 October 2024
  • Thumbnail for Lymphotoxin beta receptor
    a member of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of...
    12 KB (1,508 words) - 17:56, 19 August 2022
  • Thumbnail for RANK
    Receptor activator of nuclear factor κ B (RANK), also known as TRANCE receptor or TNFRSF11A, is a member of the tumor necrosis factor receptor (TNFR) molecular...
    23 KB (3,035 words) - 06:16, 25 December 2023
  • Thumbnail for Transmembrane activator and CAML interactor
    Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in...
    13 KB (1,629 words) - 22:42, 25 April 2024
  • Thumbnail for Herpesvirus entry mediator
    Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of...
    14 KB (1,792 words) - 22:07, 14 January 2024
  • Soluble tumor necrosis factor receptors (sTNFR) are the cleaved-off extracellular domains of transmembrane TNF receptors. They are proposed to enter the...
    1 KB (119 words) - 18:59, 12 September 2024
  • Thumbnail for TNFRSF18
    Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as glucocorticoid-induced TNFR-related protein (GITR) or CD357. GITR is encoded...
    19 KB (2,117 words) - 05:46, 27 April 2024