When TNF binds to its target receptors, tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2), a pathway of signals is...
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The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers...
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TNF receptor superfamily (redirect from Receptors, tumor necrosis factor)
The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis...
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Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane...
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TNF inhibitor (redirect from Tumor necrosis factor inhibitor)
pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response. TNF is involved...
33 KB (3,686 words) - 07:30, 20 May 2024
Tumor necrosis factor receptor 2 (TNFR2), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) and CD120b, is one of two membrane...
12 KB (1,387 words) - 13:47, 4 September 2024
Lymphotoxin alpha (redirect from Tumor necrosis factor-beta)
Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA gene. Belonging to the...
24 KB (2,809 words) - 11:12, 20 August 2024
Lymphotoxin (redirect from Tumor-necrosis factor β)
Lymphotoxin is a member of the tumor necrosis factor (TNF) superfamily of cytokines, whose members are responsible for regulating the growth and function...
12 KB (1,459 words) - 03:14, 30 October 2022
Hussain; Shawana, Summayya (2020). "Dysregulated epidermal growth factor and tumor growth factor-beta receptor signaling through GFAP-ACTA2 protein interaction...
70 KB (8,486 words) - 02:10, 19 August 2024
Fas receptor (redirect from Tumor necrosis factor receptor superfamily member 6)
antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans...
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TNF receptor associated periodic syndrome (redirect from Tumor necrosis factor receptor associated periodic syndrome)
syndrome associated with mutations in a receptor for the molecule tumor necrosis factor (TNF) that is inheritable in an autosomal dominant manner. Individuals...
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RANKL (redirect from Osteoclast differentiation factor)
Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
28 KB (3,309 words) - 05:21, 5 August 2024
Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein that in humans is encoded by the TRADD gene. TRADD is an adaptor protein...
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ADAM17 (redirect from Tumor Necrosis Factor Alpha Converting Enzyme)
disintegrin and metalloprotease 17 (ADAM17), also called TACE (tumor necrosis factor-α-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM...
21 KB (2,452 words) - 05:03, 26 August 2024
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans...
25 KB (3,095 words) - 14:05, 12 March 2024
Inflammaging (section Tumor necrosis factor-alpha)
by the inflammasome to induce the mature, active form of IL-1B. Tumor necrosis factor-alpha (TNF-alpha) is an inflammatory cytokine produced upon acute...
26 KB (3,020 words) - 17:03, 14 May 2024
CD137, a member of the tumor necrosis factor (TNF) receptor family, is a type 1 transmembrane protein, expressed on surfaces of leukocytes and non-immune...
20 KB (2,323 words) - 04:58, 20 May 2024
psoriasis. These genes are on the pathway that upregulate tumor necrosis factor-α and nuclear factor κB, two genes involved in inflammation. The first gene...
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superfamily member 8), is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker. This receptor is expressed by activated, but...
13 KB (1,665 words) - 03:34, 21 December 2023
lipopolysaccharide is thought to increase lymphocyte activity and boosts tumor necrosis factor (TNF). Tsung and Norton in Surgical Oncology reported that the active...
20 KB (2,297 words) - 02:49, 4 September 2024
CD40. Tumor necrosis factors Inoue J, Ishida T, Tsukamoto N, Kobayashi N, Naito A, Azuma S, Yamamoto T (January 2000). "Tumor necrosis factor receptor-associated...
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Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as glucocorticoid-induced TNFR-related protein (GITR) or CD357. GITR is encoded...
19 KB (2,117 words) - 05:46, 27 April 2024
1–2% of individuals with the HLA-B27 genotype develop the disease. Tumor necrosis factor-alpha (TNF α) and interleukin 1 (IL-1) are also implicated in ankylosing...
56 KB (5,996 words) - 13:08, 3 September 2024
a member of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of...
12 KB (1,508 words) - 17:56, 19 August 2022
Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in...
13 KB (1,629 words) - 22:42, 25 April 2024
designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10). In humans, the gene that encodes...
11 KB (1,335 words) - 12:37, 19 July 2024
Receptor activator of nuclear factor κ B (RANK), also known as TRANCE receptor or TNFRSF11A, is a member of the tumor necrosis factor receptor (TNFR) molecular...
23 KB (3,035 words) - 06:16, 25 December 2023
mediators, tumor necrosis factor alpha (TNF), interferon gamma, interleukin 2 (IL-2), IL-8, IL-10, IL-12, IL-18, IL-23 and transforming growth factor beta (TGF-β)...
118 KB (12,860 words) - 03:15, 27 August 2024
also known as tumor necrosis factor receptor superfamily member 25 (TNFRSF25), is a cell surface receptor of the tumor necrosis factor receptor superfamily...
12 KB (1,592 words) - 05:47, 28 March 2024
TNFSF15 gene. VEGI is an anti-angiogenic protein. It belongs to tumor necrosis factor (ligand) superfamily, where it is member 15. It is the sole known...
10 KB (1,378 words) - 23:28, 27 March 2024