U.S. Route 52 (US 52) is a major United States highway in the central United States that extends from the northern to southeastern region of the United...

special routes of U.S. Route 52 exist, from North Dakota to South Carolina. In order from northwest to southeast, they are as follows. U.S. Route 52 Business...

miles (509.0 km) from U.S. Route 321, near Tarboro, South Carolina, to U.S. Route 52, in Mount Airy, North Carolina. In North Carolina, it is one of the...

U.S. Route 59 (US 59) is a north–south United States highway (though it was signed east–west in parts of Texas). A latecomer to the U.S. numbered route...

U.S. Route 52 (US 52) in Virginia runs north–south through the southwestern part of the state along the Interstate 77 (I-77) corridor. Though an even-numbered...

Interstate 81 (I-81) / U.S. Route 52 (US 52) in Wytheville. Despite the "1" indicating that it is a major north–south highway, US 21 only travels through...

U.S. Route 52 (US 52) is a north–south United States highway that runs for 150 miles (240 km) from the South Carolina state line, near McFarlan, to the...

U.S. Route 52 (US 52) skirts the western fringes of the U.S. state of West Virginia. It runs from the Virginia state line near Bluefield, where it is...

U.S. Route 52 in Sabula, Iowa. US 67 crosses the Mississippi River twice along its routing. The first crossing is at West Alton, Missouri, where US 67...

U.S. Route 52 (US 52) in the state of Illinois is a surface road that traverses the north central and eastern portions of the state. It runs from the Dale...

U.S. Highway 52 (US 52) enters the state of Minnesota at the unincorporated community of Prosper, north of the town of Burr Oak, Iowa. The route is marked...

U.S. Route 52 (US 52) runs east–west across the southern part of the state of Ohio along the Ohio River, passing through or very near the cities and towns...

U.S. Highway 52 (US 52) is a 166-mile-long (267 km) United States Numbered Highway in northeast Iowa. The route begins at the Dale Gardner Veterans Memorial...

U.S. Route 52 (US 52) is an east–west United States Numbered Highway that runs for 159.960-mile (257.431 km) from Charleston to the North Carolina state...

U.S. Route 54 (US 54) is an east–west United States Highway that runs northeast–southwest for 1,197 miles (1,926 km) from El Paso, Texas, to Griggsville...

U.S. Route 76 (US 76) is an east–west U.S. highway in the Southeastern United States that travels for 548 miles (882 km). Its western terminus is at US...

U.S. Highway 52 (US 52) is a 362-mile-long (583 km) United States Numbered Highway in the U.S. state of North Dakota, which travels from the Canada–United...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside...

U.S. Route 401 (US 401) is a north–south United States highway, a spur of U.S. Route 1, that travels along the Fall Line from Sumter, South Carolina to...

U.S. Route 136 is an east-west U.S. highway that is a spur route of U.S. Route 36. It runs from Edison, Nebraska, at U.S. Route 6 and U.S. Route 34 to...

U.S. Route 165 is a north–south United States highway spur of U.S. Highway 65. It currently runs for 412 miles (663 km) from U.S. Route 90 in Iowa, Louisiana...

Dubuque, US 61/US 151 joins with US 52 and shares a route with US 52 until it veers south in Key West. In Wisconsin, US 61/US 151 joins with Wisconsin Highway 35...

U.S. Route 221 (US 221) is a 734-mile-long (1,181 km) spur of U.S. Route 21. It travels from Perry, Florida, at US 19/US 98/US 27 Alternate to Lynchburg...

southern terminus in Davenport, Iowa, U.S. Highway 55 initially followed the route of present-day U.S. Highway 52 through Hampton, Minnesota excepting...

U.S. Route 281 (US 281) is a north–south United States Numbered Highway. At 1,875 miles (3,018 km) it is the longest continuous three-digit U.S. Route...

U.S. Route 63 (US 63) is a 1,286-mile (2,070 km), north–south United States Highway primarily in the Midwestern and Southern United States. The southern...

period shortly after the route was established, it has not connected to its parent route. US 311 begins in Winston-Salem, at US 52/NC 8 (exit 110B) in the...

connects U.S. Route 62 U.S. Route 75 (US 62/US 75) in Henryetta with U.S. Route 64 (US 64) in Warner. The highway no longer meets the former route of its...

U.S. Route 180 is an east–west United States highway. Like many three-digit routes, US 180 no longer meets its "parent", US 80. US 80 was decommissioned...

U.S. Route 10 or U.S. Highway 10 (US 10) is an east–west United States Numbered Highway located in the Midwest and Great Lakes regions of the U.S. Despite...