The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports...
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solute carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2...
24 KB (2,683 words) - 19:14, 20 December 2024
Vesicular monoamine transporter 1 (VMAT1) also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 member 1 (SLC18A1) is a...
16 KB (1,962 words) - 22:11, 12 March 2024
Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine...
21 KB (2,342 words) - 15:34, 14 September 2024
serotonin transporter (SERT), and the norepinephrine transporter (NET) in the outer cell membrane and the vesicular monoamine transporter (VMAT1 and...
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Reuptake inhibitor (redirect from Vesicular transporter blocker)
hemicholinium-3, triethylcholine Vesicular acetylcholine transporter (VAChT) inhibitor – vesamicol Vesicular monoamine transporter (VMAT) inhibitor – reserpine...
19 KB (1,917 words) - 07:07, 23 November 2024
the direction of the vesicular monoamine transporter 2 (VMAT2), thereby additionally resulting in efflux of vesicular monoamine neurotransmitter into...
181 KB (12,434 words) - 01:54, 19 December 2024
widely accepted model for monoamine transporter function, sodium ions must bind to the extracellular domain of the transporter before dopamine can bind...
84 KB (9,030 words) - 10:39, 12 December 2024
Phenethylamine (section Monoamine releasing agent)
amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter...
54 KB (5,178 words) - 18:43, 13 December 2024
that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein that transports the neurotransmitter serotonin from the...
31 KB (3,438 words) - 05:47, 22 August 2024
Valbenazine (category Monoamine-depleting agents)
medication used to treat tardive dyskinesia. It acts as a vesicular monoamine transporter 2 (VMAT2) inhibitor. Valbenazine is used to treat tardive dyskinesia...
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Dopaminergic (section Monoamine oxidase inhibitors)
For example, certain proteins such as the dopamine transporter (DAT), vesicular monoamine transporter 2 (VMAT2), and dopamine receptors can be classified...
28 KB (2,798 words) - 01:21, 21 November 2024
is influenced by heredity and that a specific gene, called vesicular monoamine transporter 2 (VMAT2), predisposes humans towards spiritual or mystic experiences...
9 KB (1,046 words) - 11:06, 4 April 2024
Deutetrabenazine (category Monoamine-depleting agents)
Deutetrabenazine (trade name Austedo) is a vesicular monoamine transporter 2 inhibitor which is used for the treatment of chorea associated with Huntington's...
9 KB (652 words) - 03:18, 26 September 2024
by the solute carrier family 6 member 2 (SLC6A2) gene. NET is a monoamine transporter and is responsible for the sodium-chloride (Na+/Cl−)-dependent reuptake...
33 KB (3,479 words) - 15:14, 27 September 2024
Serotonin transporter (SERT) Vesicular monoamine transporter 1 (VMAT1) Vesicular monoamine transporter 2 (VMAT2) Adenosine transporters, including: Equilibrative...
9 KB (988 words) - 00:34, 19 August 2023
human dopamine neurons, as both compounds induce efflux from vesicular monoamine transporter 2 (VMAT2) and activate TAAR1 with comparable efficacy. Like...
20 KB (2,302 words) - 02:01, 24 November 2024
with human trace amine-associated receptor 1 (hTAAR1) and vesicular monoamine transporter 2 (VMAT2) in neurons. Dextroamphetamine is a more potent Central...
63 KB (22,421 words) - 04:07, 24 December 2024
using tetrabenazine (TBZ), which is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2) also known as solute carrier family 18 member 2 (SLC18A2)...
20 KB (1,888 words) - 20:12, 14 November 2024
small and large dense core vesicles by a solute carrier—a vesicular monoamine transporter, VMAT2. Dopamine is stored in these vesicles until it is ejected...
139 KB (14,295 words) - 21:14, 14 December 2024
Membrane transport protein (redirect from Membrane transporter)
Dopamine transporter (DAT) Norepinephrine transporter (NET) Serotonin transporter (SERT) Vesicular monoamine transporters (VMAT) Adenine nucleotide translocator...
25 KB (2,646 words) - 15:52, 16 December 2024
medications are used to treat tardive dyskinesia. These include the vesicular monoamine transporter 2 inhibitors tetrabenazine and deutetrabenazine. Extrapyramidal...
13 KB (1,359 words) - 06:00, 24 March 2024
The plasma membrane monoamine transporter (PMAT) is a low-affinity monoamine transporter protein which in humans is encoded by the SLC29A4 gene. It is...
13 KB (1,447 words) - 22:59, 9 March 2024
SLC22A3 (redirect from Extraneuronal monoamine transporter)
3 (SLC22A3) also known as the organic cation transporter 3 (OCT3) or extraneuronal monoamine transporter (EMT) is a protein that in humans is encoded...
11 KB (1,306 words) - 14:13, 12 March 2024
Reserpine (category Monoamine-depleting agents)
or psychosis. Reserpine irreversibly blocks the H+-coupled vesicular monoamine transporters, VMAT1 and VMAT2. VMAT1 is mostly expressed in neuroendocrine...
28 KB (2,899 words) - 15:25, 21 October 2024
inhibitors) SERTTooltip Serotonin transporter (SRIsTooltip Serotonin reuptake inhibitors) VMATsTooltip Vesicular monoamine transporters Amiodarone Amphetamines...
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Reverse transport (redirect from Transporter reversal)
the synaptic cleft via monoamine transporter-mediated release) by triggering reverse transport at vesicular monoamine transporters (specifically, VMAT1...
7 KB (584 words) - 01:21, 7 December 2020
glutamate transporters is composed of two primary subclasses: the excitatory amino acid transporter (EAAT) family and vesicular glutamate transporter (VGLUT)...
24 KB (2,828 words) - 15:14, 24 September 2023
attenuates methamphetamine-induced changes in vesicular monoamine transporter 2 immunoreactivity and monoamine depletions in the striatum". The Journal of...
13 KB (1,249 words) - 00:25, 24 August 2024
mediated via the plasma membrane transporters of these neurotransmitters and via the shared vesicular monoamine transporter (Chapter 6). Based on animal studies...
3 KB (385 words) - 19:45, 28 November 2024