5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
65 KB (7,147 words) - 05:41, 24 June 2024
5'-AMP-activated protein kinase (AMP-activated protein kinase). Protein kinase A, more precisely known as adenosine 3',5'-monophosphate (cyclic AMP)-dependent...
27 KB (2,665 words) - 17:03, 6 April 2024
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
46 KB (5,492 words) - 03:05, 21 June 2024
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase...
3 KB (296 words) - 17:06, 14 September 2023
5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein encoded by this gene...
10 KB (1,255 words) - 06:02, 24 June 2024
Adenosine monophosphate (redirect from 5'-AMP)
eukaryotic cell enzyme 5' adenosine monophosphate-activated protein kinase, or AMPK, utilizes AMP for homeostatic energy processes during times of high...
14 KB (1,255 words) - 07:33, 5 March 2024
molecules, including integrin-linked kinase (ILK) and mitogen-activated protein kinase-activated protein kinase-2 (MAPKAPK2) can also serve as PDK2. Phosphorylation...
35 KB (3,831 words) - 03:01, 8 July 2024
PKCs are activated through the same signal transduction pathway as phospholipase C. On the other hand, atypical (a)PKCs (including protein kinase Mζ and...
27 KB (2,650 words) - 21:16, 19 March 2024
transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines...
14 KB (1,626 words) - 20:50, 30 May 2024
(July 2007). "Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration". American Journal of...
149 KB (14,274 words) - 20:54, 5 July 2024
p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
14 KB (1,385 words) - 10:32, 28 April 2024
[citation needed] In the MAPK/ERK pathway, Ras activates c-Raf, followed by mitogen-activated protein kinase kinase (abbreviated as MKK, MEK, or MAP2K) and then...
11 KB (1,128 words) - 19:03, 18 September 2023
decrease in activity of the enzyme is caused by AMP-activated protein kinase, which responds to an increase in AMP concentration, and also to leptin. Since the...
34 KB (4,109 words) - 17:25, 15 June 2024
The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
14 KB (1,447 words) - 09:31, 22 December 2023
Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific protein kinases. It is involved...
19 KB (2,170 words) - 06:41, 27 May 2024
CAMK (redirect from Calcium/calmodulin-dependent protein kinase II)
an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration of intracellular...
8 KB (886 words) - 12:46, 31 January 2024
A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
14 KB (1,210 words) - 13:35, 14 June 2024
Phosphorylase kinase (PhK) is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to release glucose-1-phosphate from glycogen...
18 KB (2,153 words) - 17:04, 27 November 2023
Ca2+ /calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+ /calmodulin...
29 KB (3,458 words) - 16:39, 17 March 2024
serine/threonine kinase or Ataxia-telangiectasia mutated, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand...
50 KB (5,639 words) - 20:54, 11 March 2024
kinase (rsk) is a family of protein kinases involved in signal transduction. There are two subfamilies of rsk, p90rsk, also known as MAPK-activated protein...
5 KB (510 words) - 17:10, 16 September 2021
Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase...
11 KB (1,345 words) - 09:11, 2 January 2024
Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme (specifically, a protein kinase) that in humans...
17 KB (2,127 words) - 02:01, 8 April 2024
domain by protein kinases. Cyclic AMP-dependent protein kinases (protein kinase A) are activated by the signal chain coming from the G protein (that was...
82 KB (9,384 words) - 18:56, 11 June 2024
MTORC1 (category Protein pages needing a picture)
Arbiser JL, Bonner MY, et al. (February 2012). "Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and...
69 KB (7,803 words) - 11:01, 11 April 2024
generally activated by dimerization and substrate presentation. Receptor tyrosine kinases are part of the larger family of protein tyrosine kinases, encompassing...
28 KB (3,078 words) - 07:46, 3 June 2024
cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
8 KB (825 words) - 21:37, 20 April 2023
Myosin light-chain kinase also known as MYLK or MLCK is a serine/threonine-specific protein kinase that phosphorylates a specific myosin light chain,...
16 KB (1,731 words) - 22:49, 9 January 2024
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,829 words) - 14:24, 17 June 2024
Acetyl-CoA carboxylase (category Protein pages needing a picture)
AMP levels when the energy status of the cell is low, leading to the activation of the AMP-activated protein kinase (AMPK). AMPK is the main kinase regulator...
27 KB (2,990 words) - 21:27, 4 July 2024