• Thumbnail for Free fatty acid receptor 1
    Free fatty acid receptor 1 (FFAR1), also known as G-protein coupled receptor 40 (GPR40), is a rhodopsin-like G-protein coupled receptor that is coded...
    59 KB (7,458 words) - 19:14, 27 March 2024
  • Free fatty acid receptors (FFARs) are G-protein coupled receptors (GPRs). GPRs (also termed seven-(pass)-transmembrane domain receptors) are a large family...
    26 KB (2,804 words) - 02:55, 24 May 2024
  • Thumbnail for Free fatty acid receptor 4
    Free Fatty acid receptor 4 (FFAR4), also termed G-protein coupled receptor 120 (GPR120), is a protein that in humans is encoded (i.e., its formation is...
    62 KB (7,685 words) - 14:58, 28 October 2024
  • Thumbnail for Free fatty acid receptor 2
    Free fatty acid receptor 2 (FFAR2), also known as G-protein coupled receptor 43 (GPR43), is a rhodopsin-like G-protein coupled receptor (GPCR) encoded...
    67 KB (7,968 words) - 04:51, 2 September 2024
  • Fatty acid metabolism consists of various metabolic processes involving or closely related to fatty acids, a family of molecules classified within the...
    50 KB (5,561 words) - 07:03, 13 August 2024
  • Thumbnail for Arachidonic acid
    Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega−6 fatty acid 20:4(ω−6), or 20:4(5,8,11,14). If its precursors or diet contains linoleic acid it...
    21 KB (1,899 words) - 17:30, 2 October 2024
  • Thumbnail for Free fatty acid receptor 3
    Free fatty acid receptor 3 (FFAR3, also termed GPR41) protein is a G protein coupled receptor (i.e., GPR or GPCR) that in humans is encoded by the FFAR3...
    48 KB (6,095 words) - 16:42, 29 June 2024
  • Thumbnail for Taste receptor
    a true fat-tasting receptor. Free fatty acid receptor 4 (also termed GPR120) and to a much lesser extent free fatty acid receptor 1 (also termed GPR40)...
    42 KB (4,357 words) - 15:23, 20 October 2024
  • Thumbnail for Rhodopsin-like receptors
    receptor 6 (LGR6) GPR40-related receptor InterPro: IPR013312 Free fatty acid receptor 1 (FFAR1, GPR40) Free fatty acid receptor 2 (FFAR2, GPR43) Free...
    25 KB (2,172 words) - 01:01, 29 November 2023
  • Thumbnail for Hydroxycarboxylic acid receptor 2
    β-Hydroxybutyric acid, butyric acid, and niacin have actions that are independent of HCA2. For example: 1) β-hydroxybutyric acid activates free fatty acid receptor 3...
    50 KB (6,317 words) - 17:37, 30 March 2024
  • Thumbnail for Butyric acid
    short-chain fatty acids (SCFAs), butyrate is an agonist at the free fatty acid receptors FFAR2 and FFAR3, which function as nutrient sensors that facilitate...
    65 KB (6,434 words) - 06:44, 29 October 2024
  • Thumbnail for Fatty liver disease
    whereby the transport of fatty acids from adipose tissue to the liver is increased. Impairment or inhibition of receptor molecules (PPAR-α, PPAR-γ and...
    38 KB (3,896 words) - 12:27, 19 October 2024
  • Thumbnail for Hydroxycarboxylic acid receptor 1
    Hydroxycarboxylic acid receptor 1 (HCA1), formerly known as G protein-coupled receptor 81 (GPR81), is a protein that in humans is encoded by the HCAR1...
    6 KB (768 words) - 07:04, 23 December 2023
  • Thumbnail for Fatty-acid amide hydrolase 1
    Fatty-acid amide hydrolase 1 (FAAH) is a member of the serine hydrolase family of enzymes. It was first shown to break down anandamide (AEA), an N-acylethanolamine...
    33 KB (3,460 words) - 01:21, 16 August 2024
  • triglyceride (ester of glycerin) rather than as a free fatty acid. It is one of two essential fatty acids for humans, who must obtain it through their diet...
    32 KB (2,833 words) - 06:32, 11 October 2024
  • Thumbnail for Β-Hydroxybutyric acid
    D-β-hydroxybutyric acid is one of two primary endogenous agonists of hydroxycarboxylic acid receptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor (GPCR)....
    14 KB (1,416 words) - 04:19, 24 October 2024
  • Thumbnail for Taste
    protein-coupled receptors free fatty acid receptor 4 (also termed GPR120) and to a much lesser extent Free fatty acid receptor 1 (also termed GPR40) have been linked...
    96 KB (10,548 words) - 05:53, 27 October 2024
  • Thumbnail for Trans fat
    Trans fat (redirect from Trans fatty acid)
    Trans fat, also called trans-unsaturated fatty acids, or trans fatty acids, is a type of unsaturated fat that occurs in foods. Small amounts of trans...
    122 KB (13,840 words) - 15:24, 28 October 2024
  • Thumbnail for Medium-chain triglyceride
    triglyceride with two or three fatty acids having an aliphatic tail of 6–12 carbon atoms, i.e. a medium-chain fatty acid (MCFA). Rich food sources for...
    18 KB (1,877 words) - 05:24, 25 October 2024
  • Thumbnail for Branched-chain amino acid
    for enzymes in the metabolic pathway. Oxidation of BCAAs may increase fatty acid oxidation and play a role in obesity. Physiologically, BCAAs take on roles...
    29 KB (3,420 words) - 20:54, 29 August 2024
  • Thumbnail for Essential fatty acid interactions
    variety of fatty acids found in nature. Two classes of fatty acids are considered essential, the omega-3 and omega-6 fatty acids. Essential fatty acids are necessary...
    27 KB (2,975 words) - 06:52, 2 November 2024
  • Thumbnail for Anandamide
    Anandamide (category Fatty acid amides)
    referred to as N-arachidonoylethanolamine (AEA) is a fatty acid neurotransmitter belonging to the fatty acid derivative group known as N-Acylethanolamine (NAE)...
    22 KB (2,323 words) - 07:09, 27 August 2024
  • Thumbnail for Carnitine
    Carnitine (category Beta hydroxy acids)
    metabolism, carnitine transports long-chain fatty acids from the cytosol into mitochondria to be oxidized for free energy production, and also participates...
    30 KB (3,278 words) - 20:35, 26 April 2024
  • Thumbnail for Sebacic acid
    and free fatty acids (≈16%). Included in the free fatty acid secretions in sebum are polyunsaturated fatty acids and sebacic acid. Sebacic acid is also...
    6 KB (579 words) - 14:28, 6 July 2024
  • Thumbnail for Metabolic dysfunction–associated steatotic liver disease
    increasing fatty acid oxidation). Metabolic modulators tested in NASH include glucagon-like peptide-1 receptor agonists (GLP-1 agonists), GLP-1 and glucose-dependent...
    137 KB (15,203 words) - 03:09, 15 October 2024
  • Thumbnail for Peroxisome proliferator-activated receptor alpha
    Endogenous ligands include fatty acids such as arachidonic acid as well as other polyunsaturated fatty acids and various fatty acid-derived compounds such...
    22 KB (2,567 words) - 20:42, 4 October 2024
  • Thumbnail for Eicosanoid
    non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are, similar to arachidonic acid, around 20 carbon units in length...
    86 KB (9,651 words) - 06:41, 2 November 2024
  • Thumbnail for ZLY18
    ZLY18 (category Free fatty acid receptor 1 agonists)
    acts as an agonist of the free fatty acid receptor 1 (FFA1) and all three types of peroxisome proliferator-activated receptor (alpha, delta, and gamma)...
    5 KB (254 words) - 19:52, 23 September 2024
  • Thumbnail for Cyclooxygenase-1
    arachidonic acid primarily to PGG2, COX-1 also converts this fatty acid to small amounts of a racemic mixture of 15-Hydroxyicosatetraenoic acids (i.e., 15-HETEs)...
    18 KB (2,122 words) - 12:15, 2 June 2024
  • Thumbnail for 9-Hydroxyoctadecadienoic acid
    9-Hydroxyoctadecadienoic acid (or 9-HODE) has been used in the literature to designate either or both of two stereoisomer metabolites of the essential fatty acid, linoleic...
    29 KB (3,702 words) - 01:43, 11 December 2023