GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression...

Haploinsufficiency (deletions) of zinc-finger transcription factor GATA3 or mutations in the GATA3 gene appear to be the underlying cause of this syndrome. It...

dependent on the microbiome. Gata3+ T regs are major immunosuppressors during intestinal inflammation and T regs use Gata3 to limit tissue inflammation...

necessary. Intracellular GATA3 expression is a crucial component of T cell receptor beta (TCR𝛽) allelic exclusion in mammalian cells. GATA3 transgenic overexpression...

change. In humans: GATA1 (see also GATA1) GATA2 (see also GATA2) GATA3 (see also GATA3) GATA4 (see also GATA4) GATA5 (see also GATA5) GATA6 (see also GATA6)...

repair system in cells Hot dry rock, a form of geothermal energy production GATA3, a protein also named HDR HDR, Inc., an American architectural and engineering...

IL-4/IL-5 CD4 T cells. The key Th2 transcription factors are STAT6 and GATA3. IL-4 is the positive feedback cytokine for Th2 cells differentiation. Besides...

role in the development of the parathyroid gland. The genes, TBX1, CRKL, GATA3, GCM2, and SOX3 have also been shown to play a crucial role in the formation...

ima04as80. PMC 7162157. PMID 18432634. Ho IC, Tai TS, Pai SY (February 2009). "GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell...

PMC 1215508. PMID 16150156. Mantilla JG, Antic T, Tretiakova M (2017). "GATA3 as a valuable marker to distinguish clear cell papillary renal cell carcinomas...

cells (Tregs) to modulate gut immunity, thus increasing the expression of Gata3 and FoxP3 genes. The colonization of Clostridium spp. can enhance the aggregation...

inherited risk factors include mutations in ARID5B, CDKN2A/2B, CEBPE, IKZF1, GATA3, PIP4K2A and, more rarely, TP53. These genes play important roles in cellular...

specific genes, many of which have been identified in previous research (SOX2, GATA3, EYA1, FOXG1, BMP4, RAC1, and more), to undergo such differentiation. Specifically...

expression analysis of two T helper master transcription factors, T-bet and GATA3, in rainbow trout Oncorhynchus mykiss and analysis of their expression during...

expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3". Molecular and Cellular Biology. 18 (12): 6939–6950. doi:10.1128/MCB.18...

fundamental transcription factors RORα and GATA3. GATA3 is also required for maintenance of ILC2 function, with GATA3 deprivation inhibiting the development...

HGNC:4164 P01350 6084 GATA1 HGNC:4170 P15976 6085 GATA2 HGNC:4171 P23769 6086 GATA3 HGNC:4172 P23771 6087 GATA4 HGNC:4173 P43694 6088 GATA5 HGNC:15802 Q9BWX5...

ENSG00000179348 GATA Known motif – High-throughput in vitro [290] VHGATAHSV GATA3 ENSG00000107485 GATA Known motif – High-throughput in vitro [291] HGATAAVV...

the nucleus in differentiated keratinocytes. It has also been shown that GATA3 induces differentiation of primary keratinocytes, and suggested that it...

encoding protein FERM and PDZ domain containing 2 GATA3: encoding the GATA3 transcription factor. GATA3 is critical for the embryonic development of the...

treatment of estrogen receptor negative androgen receptor positive luminal (GATA3 expressing) breast cancer. The regimen was designed in order to mimic the...

post-translational modification. FOXA1 in breast cancer is highly correlated with ERα+, GATA3+, and PR+ protein expression as well as endocrine signaling. FOXA1 acts...

role in the development of the parathyroid gland. The genes, TBX1, CRKL, GATA3, GCM2, and SOX3 have also been shown to play a crucial role in the formation...

of the body. This development may be regulated by the genes EYA1, SIX1, GATA3, and TBX1. The organ of Corti develops inside the cochlear duct. The cochlear...

carcinoma distinct from ductal carcinoma; FOXA1 elevated in lobular carcinoma, GATA3 elevated in ductal carcinoma; lobular carcinoma enriched for PTEN loss and...

Autosomal recessive spastic paraplegia Barakat syndrome (HDR syndrome) 146255 GATA3 Basal cell nevus syndrome 109400 PTCH1, PTCH2, SUFU Branchio‐oculo‐facial...

by a type 2 helper T cell (Th2). By targeting the transcription factor, GATA3, of the Th2 pathway, with DNAzyme it may be possible to negate the inflammation...

defining gene for ER+ luminal breast cancer, as is another pioneer factor GATA3. FOXA1 particularly is expressed in 90% of breast cancer metastases and...

IL-5 expression is regulated by several transcription factors including GATA3. IL-5 has long been associated with the cause of several allergic diseases...

pathways in the lymphocyte. This up-regulation is directly controlled by GATA3 transcription factor. IL-33 combined with IL-2, IL-7 or TSLP also stimulates...