Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine...
25 KB (2,795 words) - 01:05, 8 November 2024
increasingly common. Resistance to multiple antibiotics, including the macrolide azithromycin, which until recently was the most reliable treatment, is...
45 KB (4,972 words) - 19:18, 13 January 2025
Azithromycin (category Macrolide antibiotics)
confirmed, but it is likely safe. Azithromycin is an azalide, a type of macrolide antibiotic. It works by decreasing the production of protein, thereby...
63 KB (5,711 words) - 23:09, 6 February 2025
Erythromycin (category Macrolide antibiotics)
also applies if taken directly by the baby during this age. It is in the macrolide family of antibiotics and works by decreasing bacterial protein production...
42 KB (3,900 words) - 06:17, 16 January 2025
phenotype known as iMLSB. This phenotype of bacteria are resistant to the macrolide-lincosamide-streptogramin B group of antibiotics, however, the resistance...
44 KB (4,070 words) - 14:49, 12 January 2025
In enzymology, a macrolide 2'-kinase (EC 2.7.1.136) is an enzyme that catalyzes the chemical reaction ATP + oleandomycin ⇌ {\displaystyle \rightleftharpoons...
1 KB (135 words) - 13:52, 11 January 2024
respiratory distress. Treatment of M. pneumoniae infections typically involves macrolides or tetracyclines, as these antibiotics inhibit protein synthesis, though...
43 KB (4,676 words) - 19:50, 9 January 2025
Clarithromycin (category Macrolide antibiotics)
been reported. It may cause harm if taken during pregnancy. It is in the macrolide class and works by slowing down bacterial protein synthesis. Clarithromycin...
29 KB (2,711 words) - 13:44, 6 February 2025
One important application are the many macrocyclic antibiotics, the macrolides, e.g. clarithromycin. Many metallocofactors are bound to macrocyclic ligands...
27 KB (3,281 words) - 02:04, 3 January 2025
either alone (mild to moderate severity disease) or in combination with a macrolide. Research suggests that is as effective as co-amoxiclav (a broad-spectrum...
50 KB (4,586 words) - 14:44, 12 January 2025
Rachel Fuller Brown and Elizabeth Lee Hazen. It was the first polyene macrolide antifungal. It is on the World Health Organization's List of Essential...
29 KB (2,621 words) - 15:18, 12 January 2025
but as an indicator it is not accurate enough to decide whether or not macrolide treatment should be used. The presence of chest pain in children with...
121 KB (12,803 words) - 11:15, 11 January 2025
Ivermectin (category Macrolides)
Ivermectin is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis...
75 KB (7,326 words) - 05:54, 30 January 2025
clarithromycin, or azithromycin are typically the recommended treatment. Newer macrolides are frequently recommended due to lower rates of side effects....
50 KB (4,830 words) - 01:24, 20 December 2024
lead to asthma. Macrolide antibiotic treatment can improve asthma in a subgroup of patients that remains to be clearly defined. Macrolide benefits were...
24 KB (2,612 words) - 10:47, 18 January 2025
the genus Saccharopolyspora. Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin. Cytochrome P450 eryF (CYP107A1) originally from...
3 KB (297 words) - 11:54, 13 May 2024
minimal relief provided for asthma symptoms. Macrolide antibiotics, particularly the azalide macrolide azithromycin, are a recently added Global Initiative...
169 KB (18,192 words) - 14:28, 3 February 2025
formula C18H34O2. It is a cyclic ester or lactone, more specifically a macrolide. Several species of bees (such as some of genera Colletes, Halictus, Lasioglossum)...
2 KB (181 words) - 20:43, 2 November 2024
Azalide (category Macrolide antibiotics)
a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides (erythromycin)...
4 KB (366 words) - 08:32, 16 February 2024
their tonsils. A drug-resistant strain of scarlet fever, resistant to macrolide antibiotics such as erythromycin, but retaining drug-sensitivity to beta-lactam...
63 KB (6,745 words) - 18:09, 14 January 2025
cephalosporins, monobactams (aztreonam), aminoglycosides, quinolones, macrolides, chloramphenicol, folate antagonists, and carbapenems. The adjectives...
25 KB (2,514 words) - 19:44, 25 January 2025
complexes, including macrolides, tetracycline, ketolides, and fluoroquinolone, many of which can be administered orally. Macrolides are capable of reducing...
18 KB (2,018 words) - 17:53, 16 December 2024
such as certain anti-arrhythmics, anti-depressants, and quinolone or macrolide antibiotics. Although it is not recognized as an inherited condition,...
124 KB (13,680 words) - 05:57, 4 February 2025
ISBN 978-0-9626523-7-0. Rodvold KA, Piscitelli SC (August 1993). "New oral macrolide and fluoroquinolone antibiotics: an overview of pharmacokinetics, interactions...
66 KB (6,684 words) - 19:26, 2 December 2024
bactericidal activities, killing the bacteria. Protein synthesis inhibitors (macrolides, lincosamides, and tetracyclines) are usually bacteriostatic, inhibiting...
156 KB (14,668 words) - 08:21, 17 January 2025
the overarching water safety plan. Effective antibiotics include most macrolides, tetracyclines, ketolides, and quinolones. Legionella spp. multiply within...
59 KB (5,885 words) - 04:20, 30 January 2025
especially to the commonly used tetracycline (e.g., doxycycline) and macrolide antibiotics (e.g., topical erythromycin). Therefore, dermatologists prefer...
166 KB (18,062 words) - 12:50, 10 January 2025
Tildipirosin, sold under the brand name Zuprevo, is a macrolide antibiotic used in pigs and cattle. In the United States, tildipirosin is indicated for...
6 KB (173 words) - 15:55, 24 October 2024
Spiramycin (category Macrolide antibiotics)
Spiramycin is a macrolide antibiotic and antiparasitic. It is used to treat toxoplasmosis and various other infections of soft tissues. Although used...
7 KB (466 words) - 05:48, 4 January 2025
recommended. In those who are allergic to penicillin, cephalosporins or macrolides may be used. In children with frequent episodes of tonsillitis, tonsillectomy...
34 KB (3,443 words) - 15:44, 4 February 2025