Omalizumab, sold under the brand name Xolair among others, is an injectable medication to treat severe persistent allergic forms of asthma, nasal polyps...
47 KB (4,922 words) - 13:34, 12 November 2024
control. Experimentally, a low dose of methotrexate or cyclosporin and omalizumab (a monoclonal anti-IgE antibody) has been used. Treatment of autoimmune...
21 KB (1,860 words) - 04:32, 30 October 2024
Pharmacotherapy (section Example: Omalizumab Therapy)
in allergic reactions. The efficacy of omalizumab may vary among patients. To identify responders to omalizumab, the level of several biomarkers can be...
28 KB (3,050 words) - 12:24, 6 August 2024
long term antihistamine therapy is indicated. Immunosuppressants such as omalizumab or cyclosporin may also be used. About 20% of people are affected at some...
50 KB (5,773 words) - 13:12, 19 November 2024
includes the use of antihistamines, corticosteroids, monoclonal antibodies (omalizumab), and in some cases, immunosuppressive drugs. Despite ongoing research...
35 KB (3,673 words) - 06:34, 15 January 2024
phase I to IV clinical trials of omalizumab in various indications, concluded that a causal relationship between omalizumab therapy and malignancy is unlikely...
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off-label therapy with cyclosporine A or montelukast or add-on therapy with omalizumab, which is an approved treatment option for CSU. Angioedema, excruciatingly...
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cells and thereby help prevent acute rejection of kidney transplants. Omalizumab inhibits human immunoglobulin E (IgE) and is useful in treating moderate-to-severe...
48 KB (4,964 words) - 04:26, 20 October 2024
marboxil), for influenza A and B (both treatment and prevention). Xolair (omalizumab), for asthma, chronic idiopathic urticaria (CIU), and nasal polyps. Zelboraf...
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avoid food allergies, azathioprine and antibodies, including mepolizumab, omalizumab, infliximab, and adalimumab. The word enteritis (/ˌɛntəˈraɪtɪs/) uses...
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CU is rather limited in most cases. Treatment(s) with mixed success: omalizumab (anti-IgE therapy), danazol (synthetic androgen), propranolol (beta blocker)...
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approaches to reducing autumn exacerbations, but while costly, seasonal omalizumab treatment from four to six weeks before school return may reduce autumn...
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Food allergy (section Omalizumab)
have generally been used to treat peanut and environmental allergies. Omalizumab, an injectable asthma treatment drug sold under the brand name Xolair...
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to OIT to reduce immune response. In 1 trial, the monoclonal antibody omalizumab was combined with high-dose milk oral immunotherapy and saw positive results...
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have dangerous reactions to these drugs Monoclonal antibodies, such as omalizumab Corticosteroids The prognosis of MCAS is uncertain. The condition was...
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as of December 2021. Subcutaneous injection of the anti-IgE antibody omalizumab is being studied as a method of preventing recurrence, but it is not yet...
58 KB (6,223 words) - 04:36, 29 October 2024
International Nonproprietary Names of humanized antibodies end in -zumab, as in omalizumab (see Nomenclature of monoclonal antibodies). Humanized antibodies are...
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Twinject) for use in the event of a serious reaction. Studies have found that omalizumab (Xolair) may be an effective and safe treatment for cold urticaria in...
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has been shown to reduce viral load and pro-inflammatory IL-1β in mice. Omalizumab, which was developed for treatment of severe allergic asthma, has shown...
30 KB (3,488 words) - 21:50, 20 November 2024
Prevention of bone fractures in cancer patients 1,288 2012 −13% Xolair (omalizumab) Moderate-to-severe asthma not controlled by inhaled steroids Chronic...
144 KB (12,146 words) - 09:25, 31 October 2024
"Clot-busting" drug to treat acute myocardial infarction. 2003: Xolair (omalizumab): Subcutaneous injection for moderate to severe persistent asthma. 2003:...
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mycophenolate, and azathioprine. Newer targeted medications, including omalizumab and belimumab, have also been used. Urticarial vasculitis is featured...
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Rachid R, Gragg H, Little SV, Lakin P, Cianferoni A, et al. (March 2017). "Omalizumab facilitates rapid oral desensitization for peanut allergy". The Journal...
59 KB (6,137 words) - 22:03, 11 October 2024
treatment options with oral corticosteroids, biological treatments (e.g. omalizumab, mepolizumab) or allergen immunotherapy. Eczema Asthma Rhinitis Anaphylaxis...
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asthma symptomatic control include omalizumab, mepolizumab, reslizumab, benralizumab, dupilumab and tezepelumab. Omalizumab binds to free human immunoglobulin...
27 KB (2,763 words) - 15:14, 19 November 2024
joint steering committee formed by members from the three companies chose omalizumab (trade name Xolair) developed by Genentech for further development, on...
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of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for...
14 KB (1,549 words) - 14:59, 25 October 2024
medicine in asthma and food allergies. Umetsu's research has shown that omalizumab, an anti-IgE monoclonal antibody, marketed as Xolair by Genentech, can...
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et al. (2008). "Conversion of cetuximab, panitumumab, trastuzumab and omalizumab into T-cell-engaging BiTE antibodies creates novel drug candidates of...
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olvanil (INN) omacetaxine mepesuccinate (USAN) omadacycline (USAN, INN) omalizumab (INN) omapatrilat (INN) omecamtiv mecarbil (USAN, INN) omeprazole (INN)...
7 KB (377 words) - 06:40, 16 November 2024