called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk score (PRS or PR score) or genetic...

controversial paper published in 2019 claimed that a Jewish sample had higher polygenic scores for educational attainment and cognitive ability than other religious...

study population is correlated with environmental variation, then the polygenic score is no longer measuring the genetic component alone. Several methods...

Hoffmeister M, et al. (September 2020). "Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk". Am J Hum Genet. 107 (3): 432–444. doi:10...

the HFE gene. Beethoven’s polygenic score for cirrhosis was in agreement with these findings, placing him in the 96th polygenic risk percentile, and conferring...

phenotypic trait, which varies in degree and which can be attributed to polygenic effects, i.e., the product of two or more genes, and their environment...

influence both traits. Genetic correlations can be used in GWASes by using polygenic scores or genome-wide hits for one (often more easily measured) trait to increase...

linkage disequilibrium score regression (LDSR or LDSC) is a technique that aims to quantify the separate contributions of polygenic effects and various confounding...

genome-wide approaches. As an example for the latter, Keers et al. created a polygenic score for Environmental Sensitivity based on about 25,000 gene variants across...

found evidence for gene–environment interaction. A polygenic score (PGS; also called a polygenic risk score), which is a number assigned to individuals based...

Polygenic adaptation describes a process in which a population adapts through small changes in allele frequencies at hundreds or thousands of loci. Many...

tests (including tests from 23andMe and Ancestry.com) to calculate polygenic risk scores (PRS) for complex diseases and cognitive and personality traits...

years old), the Framingham Risk Score remains below 10–12% for all deciles of baseline-predicted risk. Polygenic score is another way of risk assessment...

Behavioural Therapy (CBT). This work resulted in the creation of a polygenic score for sensitivity to the environment that he found to moderate the effects...

interaction Genomics Linkage disequilibrium Molecular epidemiology Polygenic score Population genetics Genetic epidemiology Common disease-common variant...

Kotar (Croatian: Primorsko goranski savez), a Croatian political party Polygenic score, estimated effect of genetic variants Presentation Graphic Stream,...

for social reasons. Bioethics Designer baby Family-based QTL mapping Polygenic score Sperm sorting "PGD / PGS – A boon for couples with genetic issues –...

Retrieved 20 November 2019. LeMieux, Julianna (1 April 2019). "Polygenic Risk Scores and Genomic Prediction: Q&A with Stephen Hsu". Genetic Engineering...

associated with genetic sensitivity. For example, Keers et al. created a polygenic score for environmental sensitivity based on thousands of gene variants and...

could interact with multiple genes, a polygenic approach can be taken to analyze GxE interactions. A polygenic score is generated using the alleles associated...

Genome-wide Association Studies (GWAS) as well as the design and accuracy of polygenic scores. GCTA estimates from common variants are typically substantially lower...

collaboration with Rahul Desikan and Chun Fan, Dale has developed a polygenic score for quantifying the 'personalized' risk for quantifying Alzheimer's...

risk factors was combined and calculated into what was called a polygenic risk score, placing the individual on a spectrum of risk with regard to that...

Retrieved 14 November 2022. "Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals"...

differences in intelligence between races as definitively false. Analysis of polygenic scores sampled from the 1000 Genomes Project has likewise found no evidence...

in the late nineteenth century. Intelligence in the normal range is a polygenic trait, meaning that it is influenced by more than one gene, and in the...

in Atlanta, Georgia, United States. Much of her research focused on polygenic score-based genetic risk prediction for complex diseases like diabetes and...

imagination for learning; and (3) the relationship between genome-wide polygenic scores and educational attainment. von Stumm, S., Hell, B., & Chamorro-Premuzic...

tests to select people for education and employment. He suggests that polygenic scores might supplement testing in a manner that is essentially free of biases...

Psychiatric Genetics at Oxford University. Naomi pioneered the use of polygenic scores in human genetics, and has made significant contributions to both the...