• Thumbnail for Pseudouridine
    Pseudouridine (5-ribosyluracil, abbreviated by the Greek letter psi- Ψ) is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon...
    24 KB (2,835 words) - 06:46, 28 July 2024
  • In enzymology, a pseudouridine kinase (EC 2.7.1.83) is an enzyme that catalyzes the chemical reaction ATP + pseudouridine ⇌ {\displaystyle \rightleftharpoons...
    2 KB (130 words) - 15:36, 26 August 2023
  • In enzymology, a tRNA-pseudouridine synthase I (EC 5.4.99.12) is an enzyme that catalyzes the chemical reaction tRNA uridine ⇌ {\displaystyle \rightleftharpoons...
    2 KB (189 words) - 16:08, 26 August 2023
  • Pseudouridine synthase RluA may refer to: TRNA pseudouridine32 synthase, an enzyme 23S rRNA pseudouridine746 synthase, an enzyme This set index page lists...
    457 bytes (50 words) - 15:26, 6 February 2015
  • Thumbnail for Katalin Karikó
    in mRNA led to a reduced immune response: by replacing uridine with pseudouridine. Their key finding of a chemical modification of mRNA to render it non-immunogenic...
    42 KB (4,538 words) - 17:55, 24 August 2024
  • tRNA pseudouridine38/39 synthase (EC 5.4.99.45, Deg1, Pus3p, pseudouridine synthase 3) is an enzyme with systematic name tRNA-uridine38/39 uracil mutase...
    2 KB (158 words) - 16:08, 26 August 2023
  • Thumbnail for RNA
    attached sugars can be modified in numerous ways as the RNAs mature. Pseudouridine (Ψ), in which the linkage between uracil and ribose is changed from...
    65 KB (7,606 words) - 20:16, 12 August 2024
  • Thumbnail for N1-Methylpseudouridine
    elasomeran (Moderna). N1-Methylpseudouridine is the methylated derivative of pseudouridine. It is used in in vitro transcription and for the production of RNA...
    16 KB (1,510 words) - 19:37, 11 April 2024
  • PsiI516 synthase, 16S RNA Psi516 synthase, RNA pseudouridine synthase RsuA, RsuA, 16S RNA pseudouridine 516 synthase) is an enzyme with systematic name...
    2 KB (213 words) - 12:51, 26 August 2023
  • pseudouridine1911/1915/1917 synthase (also known as RluD)(EC 5.4.99.23, RluD, pseudouridine synthase RluD) is an enzyme with systematic name 23S rRNA-uridine1911/1915/1917...
    3 KB (268 words) - 12:52, 26 August 2023
  • uracil + D-ribose 5-phosphate ⇌ {\displaystyle \rightleftharpoons } pseudouridine 5′-phosphate + H2O This enzyme belongs to the family of lyases, specifically...
    3 KB (268 words) - 15:36, 26 August 2023
  • Thumbnail for 2023 Nobel Prize in Physiology or Medicine
    Ludwig, J., Kato, H., Akira, S. and Weissman, D. Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational...
    7 KB (535 words) - 23:18, 17 February 2024
  • Thumbnail for Nucleotide base
    are many modified bases, including those contained in the nucleosides pseudouridine (Ψ), dihydrouridine (D), inosine (I), and 7-methylguanosine (m7G). Hypoxanthine...
    15 KB (1,434 words) - 14:39, 12 August 2024
  • YNL292w (gene), Psi55 tRNA pseudouridine synthase, tRNA:Psi55-synthase, tRNA pseudouridine 55 synthase, tRNA:pseudouridine-55 synthase, Psi55 synthase...
    3 KB (345 words) - 16:08, 26 August 2023
  • 23S rRNA pseudouridine955/2504/2580 synthase (EC 5.4.99.24, RluC, pseudouridine synthase RluC) is an enzyme with systematic name 23S rRNA-uridine955/2504/2580...
    3 KB (280 words) - 12:52, 26 August 2023
  • TruD, YgbO, tRNA PSI13 synthase, RNA:PSI-synthase Pus7p, Pus7p, RNA:pseudouridine-synthase Pus7p, Pus7 protein) is an enzyme with systematic name tRNA-uridine13...
    3 KB (291 words) - 16:07, 26 August 2023
  • Thumbnail for Psi (Greek)
    movement of water between plant cells. In biochemistry, it denotes pseudouridine, an uncommon nucleoside. Stream function in fluid mechanics defining...
    7 KB (734 words) - 00:02, 4 June 2024
  • interactions (pseudouridine contains an extra hydrogen bond donor). When it comes to Watson-Crick base pair interactions, the pseudouridine-adenosine base...
    61 KB (7,732 words) - 20:34, 13 May 2024
  • Thumbnail for Spliceosome
    the nucleophile for the first transesterification. The presence of a pseudouridine residue in U2 snRNA, nearly opposite of the branch site, results in...
    21 KB (2,635 words) - 23:46, 24 July 2024
  • Thumbnail for Epitranscriptomic sequencing
    2'-O-dimethyladenosine, 5-methylcytidine, 5-hydroxylmethylcytidine, inosine, and pseudouridine. Various sequencing methods have been developed to profile each type...
    51 KB (6,385 words) - 15:50, 26 April 2024
  • Mitochondrial tRNA pseudouridine27/28 synthase (EC 5.4.99.44, Pus2, Pus2p, RNA:pseudouridine synthases 2) is an enzyme with systematic name mitochondrial tRNA-uridine27/28...
    1 KB (122 words) - 14:58, 26 August 2023
  • (pseudouridine1915-N3)-methyltransferase (EC 2.1.1.177, YbeA, RlmH, pseudouridine methyltransferase, m3Psi methyltransferase, Psi1915-specific methyltransferase...
    2 KB (162 words) - 12:52, 26 August 2023
  • (EC 5.4.99.29, RluA, 23S RNA PSI746 synthase, 23S rRNA pseudouridine synthase, pseudouridine synthase RluA) is an enzyme with systematic name 23S rRNA-uridine746...
    2 KB (228 words) - 12:52, 26 August 2023
  • Thumbnail for Uremia
    gut bacteria Polyols CMPF unknown tightly protein bound Ucleosides pseudouridine tRNA most prominent of several altered RNA species Dicarboxylic acids...
    33 KB (3,274 words) - 05:34, 21 July 2024
  • RRNA small subunit pseudouridine methyltransferase Nep1 (EC 2.1.1.260, Nep1, nucleolar essential protein 1) is an enzyme with systematic name...
    4 KB (450 words) - 15:45, 26 August 2023
  • provided to the RNA polymerase include non-standard nucleosides such as pseudouridine — instead of the standard adenosine, cytidine, guanosine, and uridine...
    24 KB (2,503 words) - 11:29, 22 February 2024
  • synonymously with 'ligase'. ATP synthase Citrate synthase Tryptophan synthase Pseudouridine synthase Fatty acid synthase Cellulose synthase (UDP-forming) Cellulose...
    1 KB (120 words) - 21:07, 7 February 2024
  • Thumbnail for Gene expression
    more rRNAs. The pre-rRNA is cleaved and modified (2′-O-methylation and pseudouridine formation) at specific sites by approximately 150 different small nucleolus-restricted...
    102 KB (11,438 words) - 16:50, 17 July 2024
  • Thumbnail for T arm
    known as the TΨC arm due to the presence of ribothymidine (T/m5U), pseudouridine and cytidine residues. It folds into a unique structural element consisting...
    3 KB (427 words) - 10:56, 22 August 2024
  • Thumbnail for Nucleic acid sequence
    5-methylcytidine (m5C). In RNA, there are many modified bases, including pseudouridine (Ψ), dihydrouridine (D), inosine (I), ribothymidine (rT) and 7-methylguanosine...
    22 KB (2,409 words) - 23:07, 24 August 2024