A radioligand is a microscopic particle which consists of a therapeutic radioactive isotope and the cell-targeting compound - the ligand. The ligand is...

PET radiotracer is a type of radioligand that is used for the diagnostic purposes via positron emission tomography imaging technique. PET is a functional...

radioligand concentration is high enough to saturate the protein. Denatured protein is unable to bind the radioligand and the protein and radioligand...

for a radioligand (per mole) are referred to as the specific activity (SA), which is measured in Ci/mmol. The actual concentration of a radioligand is determined...

DRUGMATRIX: Muscarinic M1 radioligand binding (Ligand: [3H] N-Methylscopolamine) - PubChem". "AID 625154 - DRUGMATRIX: Muscarinic M4 radioligand binding (Ligand:...

Nix WB, Timmerman H, Leurs R (July 2002). "A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors". The Journal of...

competitive.[citation needed] In this type of assay, a single concentration of radioligand (usually an agonist) is used in every assay tube. The ligand is used...

(such as with Lutathera and Pluvicto), the technique is also known as radioligand therapy. Iodine-131 (131I) is the most common RNT worldwide and uses...

(December 1981). "[3H]rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors". European Journal of Pharmacology...

In pharmacology, Schild regression analysis, based upon the Schild equation, both named for Heinz Otto Schild, are tools for studying the effects of agonists...

cancer (mCRPC). Lutetium (177Lu) vipivotide tetraxetan is a targeted radioligand therapy. The most common adverse reactions include fatigue, dry mouth...

(PET) in Copenhagen. Being the first 5-HT2A receptor full agonist PET radioligand, [11C]CIMBI-5 shows promise as a more functional marker of these receptors...

stereoisomer. In neuroscience research, [125I]-R-(−)-DOI is used as a radioligand and indicator of the presence of 5-HT2A serotonin receptors. DOI's effects...

with the radioactive isotope carbon-11, flumazenil may be used as a radioligand in neuroimaging with positron emission tomography to visualize the distribution...

Auger therapy Other names AT Specialty Radioligand Therapy [edit on Wikidata]...

5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modeling". Molecular...

D (June 1988). "Molecular pharmacology of 5-HT1D recognition sites: radioligand binding studies in human, pig and calf brain membranes". Naunyn-Schmiedeberg's...

dopamine D2 or D4 receptor varies with the affinity of the competing radioligand". European Journal of Pharmacology. 291 (2): 59–66. doi:10.1016/0922-4106(95)90125-6...

S2CID 29262166. Venturini G (1987). "The hydra GSH receptor. Pharmacological and radioligand binding studies". Comparative Biochemistry and Physiology. C, Comparative...

radiolabeled drug towards the receptor. For in vitro autoradiography, radioligand was directly applying on frozen tissue sections without administration...

experimentally using Schild regression or for competitive antagonists in radioligand binding studies using the Cheng-Prusoff equation. Schild regression can...

Porter AC, Neubig RR (December 1994). "The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C...

D (June 1988). "Molecular pharmacology of 5-HT1D recognition sites: radioligand binding studies in human, pig and calf brain membranes". Naunyn-Schmiedeberg's...

and ultrasound. SPECT is an imaging technique similar to PET that uses radioligands to detect molecules in the body. SPECT is less expensive and provides...

(RIT) in which a peptide or hormone conjugated to a radionuclide or radioligand is given intravenously, the peptide or neuroamine hormone previously...

side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands". Bioorganic & Medicinal Chemistry Letters. 11 (8): 1045–1047. doi:10...

gamma emitter. 90Y is a beta emitter. Radiopharmacology PET radiotracer Radioligand Isotopes in medicine Radiocontrast agent Iverson (2007), "15.9.2 Radiopharmaceuticals"...

tentative reports of increased VMAT2 activity, measured via PET scans of radioligand binding, suggests a role of dopamine in mania. Decreased cerebrospinal...

using radioligands called DASB and DAPP; the first such studies on the human brain were reported in 2000. DASB and DAPP are not the only radioligands for...

Kennett G, et al. (2004). "Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors". Naunyn-Schmiedeberg's...