The regulatory T cells (Tregs /ˈtiːrɛɡ/ or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system...
79 KB (9,493 words) - 15:51, 21 June 2024
(such as T-helper1, T-helper2, T-helper17, regulatory T-cell), which is distinguished by the types of cytokines they secrete. Regulatory T cells are yet...
71 KB (9,026 words) - 12:33, 26 April 2024
The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune...
54 KB (6,597 words) - 14:51, 21 July 2024
Immunotherapy (redirect from Regulatory T cell therapy)
Whether T cells are genetically engineered or not, before re-infusion, lympho-depletion of the recipient is required to eliminate regulatory T cells as well...
59 KB (6,128 words) - 05:06, 8 July 2024
1 regulatory cells or Tr1 (TR1) cells are a class of regulatory T cells participating in peripheral immunity as a subset of CD4+ T cells. Tr1 cells regulate...
15 KB (1,883 words) - 10:16, 22 July 2024
Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed...
35 KB (4,472 words) - 00:20, 13 June 2024
immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor proteins that have been engineered to give T cells the new ability to...
83 KB (8,682 words) - 19:28, 21 August 2024
as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response...
28 KB (3,448 words) - 17:10, 16 April 2024
Regulatory B cells (Bregs or Breg cells) represent a small population of B cells that participates in immunomodulation and in the suppression of immune...
27 KB (2,952 words) - 11:58, 22 August 2024
cells are incorporated within the naive T cell phenotype but are a different T cell subset (Treg, regulatory T cells; RTE, Recent Thymic emigrant). It is...
9 KB (1,147 words) - 07:16, 18 July 2023
These regulatory Th17 cells can be generated by TGF-beta plus IL-6 in vitro. Like conventional regulatory T cells (Treg), induction of regulatory Treg17...
31 KB (3,564 words) - 14:56, 3 December 2023
A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...
31 KB (3,843 words) - 10:18, 12 August 2024
responses. CTLA-4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly...
30 KB (3,464 words) - 22:51, 24 May 2024
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen...
43 KB (5,372 words) - 15:31, 6 August 2024
tough Killer T Cell, despite having undergone T Cell training together with him. Regulatory T Cell (制御性T細胞, Seigyosei Tī Saibō) Voiced by: Saori Hayami...
147 KB (7,337 words) - 19:24, 13 August 2024
damage. The role of regulatory T and regulatory B cells is to suppress CMI enough to prevent tissue damage. However, an excessive regulatory response can prevent...
77 KB (9,190 words) - 20:30, 8 July 2024
Immune tolerance (section Regulatory T cells)
of their B cell receptor. Some weakly self-recognizing T cells are alternatively differentiated into natural regulatory T cells (nTreg cells), which act...
50 KB (6,036 words) - 18:32, 12 August 2024
killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer cells. Many of these cells recognize...
14 KB (1,648 words) - 09:58, 18 July 2023
characteristics of regulatory T cells in lupus patients do not differ from healthy patients. However, depletion of regulatory T cells results in more intense...
24 KB (2,830 words) - 09:15, 19 March 2024
"autoreactive T cells" which recognize self antigens via their TCRs. Autoreactive T cells must be eliminated from the body or skewed into the T Regulatory cells (TRegs)...
29 KB (3,544 words) - 07:37, 20 April 2024
Thymocyte (redirect from T cell selection)
thymocyte is an immune cell present in the thymus, before it undergoes transformation into a T cell. Thymocytes are produced as stem cells in the bone marrow...
21 KB (2,589 words) - 10:38, 12 August 2024
differentiation of regulatory T cells. In particular, circulating butyrate prompts the generation of extrathymic regulatory T cells. The low-levels of...
65 KB (6,428 words) - 03:51, 25 June 2024
Memory T cells are a subset of T lymphocytes that might have some of the same functions as memory B cells. Their lineage is unclear. Antigen-specific memory...
32 KB (3,781 words) - 12:49, 26 April 2024
TGF beta 1 (section T cells)
types of cell, or cells at different developmental stages. Most immune cells (or leukocytes) secrete TGF-β1. Some T cells (e.g. regulatory T cells) release...
19 KB (2,290 words) - 20:43, 26 March 2024
conducted efforts to elucidate pathways crucial for controlling Treg (regulatory T cell) function, particularly within tumor contexts, to pinpoint potential...
30 KB (3,517 words) - 08:24, 3 July 2024
Peripheral tolerance (section Regulatory T cells)
of T cell in quiescence, ignorance of antigen and direct inactivation of effector T cells by either clonal deletion, conversion to regulatory T cells (Tregs)...
24 KB (2,978 words) - 02:08, 5 June 2024
Central tolerance (section T cell)
T cells or MHC class II in case of CD4+ T cells) to create proper interaction with antigen-presenting cell. Furthermore, TCRs of regulatory T cells (Treg...
32 KB (4,109 words) - 21:21, 17 July 2024
IL1RL1 (section Regulatory T cells)
correlation between T regulatory cell ST2 and Th2 specific transcription factor GATA3 expressions. Both molecules are present in T regulatory cells together. GATA3...
18 KB (2,424 words) - 23:12, 19 March 2024
CD4+ T cells and activated CD8+ T cells. Put shortly the function of IL-2 is to stimulate the growth of helper, cytotoxic and regulatory T cells. IL-2...
43 KB (5,000 words) - 13:28, 1 July 2024
response to self-antigens by increasing the number of precursors of a regulatory T-Cell population. In a double-blind placebo-controlled study, 11 of the...
8 KB (1,037 words) - 03:20, 5 April 2024