• Ribosomal frameshifting, also known as translational frameshifting or translational recoding, is a biological phenomenon that occurs during translation...
    27 KB (2,642 words) - 03:35, 14 August 2024
  • Thumbnail for HIV ribosomal frameshift signal
    HIV ribosomal frameshift signal is a ribosomal frameshift (PRF) that human immunodeficiency virus (HIV) uses to translate several different proteins from...
    10 KB (1,273 words) - 17:56, 13 March 2023
  • Thumbnail for DnaX ribosomal frameshifting element
    The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two encoded products, tau and...
    2 KB (164 words) - 07:27, 26 April 2020
  • Thumbnail for Slippery sequence
    UUUAAAC) that controls the rate and chance of ribosomal frameshifting. A slippery sequence causes a faster ribosomal transfer which in turn can cause the reading...
    6 KB (551 words) - 03:35, 14 August 2024
  • Thumbnail for Ribosomal pause
    synthesis. Translational frameshift HIV Ribosomal frameshift signal Coronavirus frameshifting stimulation element Ribosomal frameshift Gawroński P, Jensen...
    15 KB (1,839 words) - 20:02, 17 August 2024
  • Thumbnail for Insertion sequence IS1222 ribosomal frameshifting element
    ribosomal frameshifting element is an RNA element found in the insertion sequence IS222. The ribosomal frameshifting element stimulates frameshifting...
    2 KB (100 words) - 15:51, 11 January 2024
  • Thumbnail for Frameshift mutation
    A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number...
    36 KB (4,728 words) - 21:46, 4 October 2024
  • charges). They have also been found to act as promoters of programmed ribosomal frameshifting during translation. Inhibition of polyamine biosynthesis retards...
    15 KB (1,645 words) - 14:28, 22 June 2024
  • Thumbnail for Coronavirus
    -1 ribosomal frameshift caused by a slippery sequence (UUUAAAC) and a downstream RNA pseudoknot at the end of open reading frame ORF1a. The ribosomal frameshift...
    96 KB (10,558 words) - 14:24, 12 October 2024
  • referred to as the replicase gene. They are related by a programmed ribosomal frameshift that allows the ribosome to continue translating past the stop codon...
    17 KB (1,381 words) - 00:22, 3 December 2023
  • Thumbnail for SARS-related coronavirus
    -1 ribosomal frameshift caused by a slippery sequence (UUUAAAC) and a downstream RNA pseudoknot at the end of open reading frame ORF1a. The ribosomal frameshift...
    52 KB (5,899 words) - 06:01, 22 August 2024
  • Thumbnail for Influenza A virus
    Acid) A component of the viral RNA polymerase PA-X Arises from a ribosomal frameshift in the PA segment. Inhibits innate host immune responses, such as...
    60 KB (6,081 words) - 16:35, 18 October 2024
  • Thumbnail for Double-stranded RNA viruses
    Gag (76 kDa) and a Gag-Pol fusion protein (180 kDa) formed by a -1 ribosomal frameshift. L-A can support the replication and encapsidation in separate viral...
    17 KB (1,922 words) - 22:37, 6 September 2024
  • single-genome-length RNA. Pseudoknots also play a role in programmed ribosomal frameshifting found in some viruses and required in the replication of retroviruses...
    31 KB (3,451 words) - 20:17, 11 September 2024
  • Thumbnail for Ornithine decarboxylase antizyme
    ribosomal frameshifting which is modulated according to the cellular concentration of polyamines. High levels of polyamines induce a +1 ribosomal frameshift...
    3 KB (315 words) - 00:31, 29 November 2023
  • Thumbnail for N1-Methylpseudouridine
    promote ribosomal frameshifting. This issue is readily correctable through the replacement of slippery sequences with synonymous codons. The frameshifting is...
    16 KB (1,511 words) - 00:10, 7 October 2024
  • Thumbnail for Viral replication
    Viruses with complex transcription, for which subgenomic mRNAs, ribosomal frameshifting and proteolytic processing of polyproteins may be used. All of...
    20 KB (2,689 words) - 10:44, 1 October 2024
  • reticular formation Positive-real function in mathematics Programmed ribosomal frameshifting during mRNA translation Pseudorandom function family Pulse repetition...
    766 bytes (100 words) - 01:21, 22 May 2024
  • ORF. Non-canonical elongation and termination of translation: Ribosomal frameshifting: used by various dsDNA, dsRNA, +ssRNA, and ssRNA-RT viruses, produces...
    47 KB (5,684 words) - 02:09, 17 August 2024
  • Thumbnail for Nsp12
    A representation of the SARS genome with ORF1A, ORF1AB, and the ribosomal frameshift shown. Coronavirus nsp12 is identified and expanded; RdRp, NiRAN domains...
    10 KB (1,238 words) - 18:11, 20 July 2024
  • Thumbnail for Astrovirus
    sequence astrovirus RNA and determine the presence of three ORFs and ribosomal frameshifting 1993: Monroe et al. classify subgenomic data for astrovirus, providing...
    41 KB (5,024 words) - 06:58, 27 July 2024
  • Thumbnail for Merafloxacin
    Kratzel A, Meurs R, et al. (June 2021). "Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome". Science. 372...
    4 KB (118 words) - 11:56, 18 September 2023
  • Thumbnail for Myoviridae
    is the method of transcription. Translation takes place by -1 ribosomal frameshifting. The virus exits the host cell by lysis, and holin/endolysin/spanin...
    13 KB (1,213 words) - 19:39, 13 June 2024
  • open reading frames (2a and 2b) which are transcribed through a ribosomal frameshift mechanism. This mechanism is reliant upon a small stem-loop structure...
    3 KB (279 words) - 08:37, 15 December 2023
  • Thumbnail for LTR retrotransposon
    is then cleaved or the introduction of a frameshift between the two ORFs. Occasional ribosomal frameshifting allows the production of both proteins, while...
    24 KB (2,699 words) - 13:53, 25 July 2024
  • protein translation while it is encoding tRNA. This can trigger ribosomal frameshifting. Termination of elongation depends on eukaryotic release factors...
    15 KB (1,859 words) - 06:18, 27 May 2024
  • Thumbnail for Harold E. Varmus
    replication cycle of hepatitis B virus (with Donald Ganem); discovery of ribosomal frameshifting to make retroviral proteins (with Tyler Jacks); isolation of a...
    34 KB (3,437 words) - 06:20, 8 October 2024
  • Thumbnail for Alphacoronavirus
    the major non-structural proteins expressed as a fusion protein by ribosomal frameshift. These include regions with protease, helicase and RNA polymerase...
    8 KB (861 words) - 17:21, 27 December 2023
  • Thumbnail for Barnaviridae
    encodes the RNA dependent RNA polymerase and may be translated by ribosomal frameshifting as an ORF2-ORF3 polyprotein. The single capsid protein (ORF4) is...
    2 KB (217 words) - 06:51, 10 August 2023
  • Thumbnail for Totiviridae
    of transcription. Translation takes place by -1 ribosomal frameshifting, +1 ribosomal frameshifting, viral initiation, and RNA termination-reinitiation...
    4 KB (316 words) - 12:41, 30 January 2023