The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement. Substantia nigra is...

olfactory tubercle), the globus pallidus, the ventral pallidum, the substantia nigra, and the subthalamic nucleus. Each of these components has complex...

of dopamine-secreting neurons in an area of the midbrain called the substantia nigra. Its metabolic precursor L-DOPA can be manufactured; Levodopa, a pure...

The pars compacta (SNpc) is one of two subdivisions of the substantia nigra of the midbrain (the other being the pars reticulata); it is situated medial...

striatum. Through various pathways, the putamen is connected to the substantia nigra, the globus pallidus, the claustrum, and the thalamus, in addition...

Neuromelanin is found in large quantities in catecholaminergic cells of the substantia nigra pars compacta and locus coeruleus, giving a dark color to the structures...

is a bilateral dopaminergic pathway in the brain that connects the substantia nigra pars compacta (SNc) in the midbrain with the dorsal striatum (i.e....

Pathophysiology involves progressive degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system...

and to the substantia nigra pars reticulata. The striosomes receive input from the prefrontal cortex and give outputs to the substantia nigra pars compacta...

The pars reticulata (SNpr) is a portion of the substantia nigra and is located lateral to the pars compacta. Most of the neurons that project out of the...

features. The basal ganglia include the striatum, globus pallidus, substantia nigra and subthalamic nucleus. In primates the pallidus is divided into an...

the substantia nigra is involved in motor-planning, learning, addiction, and other functions. There are two regions within the substantia nigra – one...

substructure. Lewy bodies may be found in the midbrain (within the substantia nigra) or within the cortex. In 1910, Fritz Heinrich Lewy was studying in...

symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain. It has been used to study disease models in various animals...

the striatum, and principal direct outputs to the thalamus and the substantia nigra. The latter is made up of similar neuronal elements, has similar afferents...

nucleus, emboliform nucleus, and fastigial nucleus), and brainstem (the substantia nigra, red nucleus, olivary nuclei, and cranial nerve nuclei). Grey matter...

movement is influenced by the transmission of dopaminergic neurons to the substantia nigra. The nigrostriatal pathway is associated with conditions such as Huntington's...

next to the substantia nigra and comprises caudal magnocellular and rostral parvocellular components. The red nucleus and substantia nigra are subcortical...

accumbens include connections with the tail of the ventral tegmental area, substantia nigra, and the reticular formation of the pons. The nucleus accumbens shell...

pinkish tan due to blood capillaries), which is composed of neurons. The substantia nigra is a third colored component found in the brain that appears darker...

nucleus is located ventral to the thalamus. It is also dorsal to the substantia nigra and medial to the internal capsule. The principal type of neuron found...

with lateralized dopaminergic depletion in the substantia nigra. The dopamine pathway in the substantia nigra is essential to motor function, and commonly...

receptors are found mainly on neurons in the nucleus accumbens as well as substantia nigra, striatum, amygdala, frontal cortex and olfactory bulb and retina Also...

eye movements, the periaqueductal gray matter, the red nucleus, the substantia nigra, and the ventral tegmental area. The tegmentum is the location of several...

Cortical arousal also takes advantage of dopaminergic neurons of the substantia nigra (SN), ventral tegmenti area (VTA) and the periaqueductal grey area...

glutamate and have excitatory effects over neurons of globus pallidus and substantia nigra Zona incerta, located between fields of Forel H1 and H2. It is continuous...

found in other cells, including in the A9 dopaminergic neurons of the substantia nigra, macrophages, alveolar cells, lungs, retinal pigment epithelium, hepatocytes...

and the tegmentum (floor). The midbrain tegmentum extends from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It...

oxidation cascades. Iron overload primarily affects nerve cells in the substantia nigra and basal ganglia. Here, a slowly progressive degeneration occurs....

provides inhibitory output in the basal ganglia, the other being the substantia nigra pars reticulata. Together with the external globus pallidus (GPe),...