In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse. The release is regulated...

supramolecular assembly of lipid molecules, like a cell membrane Synaptic vesicle In human embryology Vesicle (embryology), bulge-like features of the early neural...

central nervous system synapse The synapse and synaptic vesicle cycle Major elements in chemical synaptic transmission Active zone Autapse Cooperative synapse...

space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are contained within small sacs called synaptic vesicles, and are released...

potential reaches the presynaptic bouton, the contents of the vesicles are released into the synaptic cleft and the released neurotransmitter travels across...

Synaptic vesicle glycoprotein 2A (SV2A) is a transmembrane protein belonging to a family of keratan sulfate proteoglycans, located on the synaptic vesicles...

the vesicle transiently fuses with the plasma membrane. In the context of neurotransmission, neurotransmitters are typically released from synaptic vesicles...

nervous system activity. It is caused by a temporary depletion of synaptic vesicles that house neurotransmitters in the synapse, generally produced by...

new synaptic vesicles. The exact mechanism and signaling cascade which triggers synaptic vesicle recycling is still unknown. No one method of synaptic vesicle...

packaged into synaptic vesicles that cluster beneath the axon terminal membrane on the presynaptic side (A) of a synapse. Some of these vesicles are docked...

released into the synaptic cleft via exocytosis from synaptic vesicles. Two kinds of neurotransmitter vesicles exist: large dense core vesicles and small clear...

Voltage- gated Ca++ channel Synaptic vesicle Neurotransmitter transporter Receptor Neurotransmitter Axon terminal Synaptic cleft Dendrite A neurotransmitter...

electron-dense structure, the synaptic ribbon, that holds vesicles close to the active zone. It is characterized by a tight vesicle-calcium channel coupling...

lysosome). The best studied SNAREs are those that mediate the release of synaptic vesicles containing neurotransmitters in neurons. These neuronal SNAREs are...

the SNCA gene. Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant...

chemicals. These chemicals are stored in secretory vesicles and released when needed. Synaptic vesicles are located at presynaptic terminals in neurons and...

Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene. The gene is located on the...

osmotically sensitive, contain numerous small clear synaptic vesicles, sometimes larger dense-core vesicles and frequently one or more small mitochondria....

trigger vesicle fusion act by increasing intracellular Ca2+. Synaptic vesicles commit vesicle fusion by a nerve impulse reaching the synapse, activating...

synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft...

synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neurotransmitter release. VAMP3 (known...

characterized. The pre-synaptic axon shows an increase in synaptic volume and area, an increase of synaptic vesicles, clustering of vesicles at the active zone...

directly executes fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP-25, a Q-SNARE protein, is anchored...

neurotransmitters and neuropeptides to modulate synaptic activity. Synaptic vesicles and dense core vesicles can have differential activation properties for...

acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool. In...

PMID 27141430. Despite the challenges in determining synaptic vesicle pH, the proton gradient across the vesicle membrane is of fundamental importance for its...

anaphylaxis. Levetiracetam is the S-enantiomer of etiracetam. It acts as a synaptic vesicle glycoprotein 2A (SV2A) ligand. Levetiracetam was approved for medical...

Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene. SV2A GRCh38: Ensembl release 89: ENSG00000185518 – Ensembl, May...

neuromuscular junction through degradation of the SNARE proteins required for ACh vesicle-membrane fusion. As the toxin is highly biologically active, an estimated...

early synaptic vesicle docking to the presynaptic membrane via interaction with β-neurexin or SNAP-25 late steps of Ca2+-evoked synaptic vesicle fusion...