• Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
    40 KB (4,580 words) - 05:24, 3 June 2024
  • Thumbnail for Vascular endothelial growth factor A
    Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth...
    24 KB (3,053 words) - 02:36, 28 March 2024
  • while fibroblast growth factors and vascular endothelial growth factors stimulate blood vessel differentiation (angiogenesis). Growth factor is sometimes...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Thumbnail for Vascular endothelial growth factor C
    Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor...
    27 KB (3,104 words) - 23:27, 27 March 2024
  • Thumbnail for VEGF receptor
    VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
    8 KB (755 words) - 18:51, 2 November 2023
  • Thumbnail for Vascular endothelial growth factor B
    Vascular endothelial growth factor B also known as VEGF-B is a protein that, in humans, is encoded by the VEGF-B gene. VEGF-B is a growth factor that belongs...
    14 KB (1,558 words) - 02:03, 27 November 2023
  • Thumbnail for Placental growth factor
    trophoblast. The placental growth factor (PGF) gene is a protein-coding gene and a member of the vascular endothelial growth factor (VEGF) family. The PGF...
    15 KB (1,923 words) - 12:01, 27 September 2023
  • Anti–vascular endothelial growth factor therapy, also known as anti-VEGF (/vɛdʒˈɛf/) therapy or medication, is the use of medications that block vascular endothelial...
    14 KB (1,671 words) - 12:47, 23 April 2024
  • Thumbnail for C-fos-induced growth factor
    C-fos-induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded...
    10 KB (1,253 words) - 05:14, 9 February 2024
  • Thumbnail for Vascular endothelial growth factor (VEGF) IRES A
    family represents the vascular endothelial growth factor (VEGF) internal ribosome entry site (IRES) A. VEGF is an endothelial cell mitogen with many...
    2 KB (123 words) - 05:06, 10 October 2019
  • Thumbnail for Kinase insert domain receptor
    domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. KDR is...
    6 KB (794 words) - 11:50, 18 May 2022
  • Thumbnail for Platelet-derived growth factor
    vascular endothelial growth factors B and C (VEGF-B, VEGF-C) which are active in angiogenesis and endothelial cell growth, and placenta growth factor...
    24 KB (2,877 words) - 10:08, 2 June 2024
  • Thumbnail for Vascular endothelial growth inhibitor
    Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is protein that in humans...
    10 KB (1,378 words) - 23:28, 27 March 2024
  • Thumbnail for Endothelium
    are called vascular endothelial cells whereas those in direct contact with lymph are known as lymphatic endothelial cells. Vascular endothelial cells line...
    28 KB (2,992 words) - 04:28, 28 May 2024
  • Bevacizumab (category Chemicals that do not have a ChemSpider ID assigned)
    slowing the growth of new blood vessels by inhibiting vascular endothelial growth factor A (VEGF-A), in other words anti–VEGF therapy. Bevacizumab was approved...
    74 KB (6,565 words) - 05:35, 13 June 2024
  • Thumbnail for Angiogenesis
    Angiogenesis (redirect from Vascularized)
    secrete vascular endothelial growth factor (VEGF-A) which is a proangiogenic growth factor. These biological signals activate receptors on endothelial cells...
    49 KB (5,763 words) - 10:02, 2 June 2024
  • paracrine factors (including angiogenin, vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and transforming growth factor-β (TGF-β)...
    33 KB (3,229 words) - 04:14, 17 June 2024
  • Aflibercept (category Chemicals that do not have a ChemSpider ID assigned)
    developed by Regeneron Pharmaceuticals. It is an inhibitor of vascular endothelial growth factor (VEGF). Aflibercept (Eylea) is indicated for the treatment...
    26 KB (1,884 words) - 03:37, 1 June 2024
  • Thumbnail for Vascular permeability
    Bates, D. O. & Harper, S. J. Regulation of vascular permeability by vascular endothelial growth factors. Vascul Pharmacol 39, 225-237 (2002) Patlak,...
    4 KB (469 words) - 15:49, 27 July 2023
  • Thumbnail for VEGFR1
    Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. FLT1 is a member of VEGF receptor gene family. It...
    9 KB (1,086 words) - 00:25, 5 October 2022
  • Thumbnail for Intravitreal administration
    reason intravitreal injections are used is to administer anti-vascular endothelial growth factor (anti-VEGF) therapies to treat wet age related macular degeneration...
    19 KB (2,323 words) - 20:58, 30 April 2024
  • the growth of new blood vessels from the pre-existing vasculature. FGF1 and FGF2 are more potent angiogenic factors than vascular endothelial growth factor...
    25 KB (3,123 words) - 20:10, 26 April 2024
  • Thumbnail for Neuropilin 1
    human neuropilins. NRP1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (for example, VEGFA) and...
    16 KB (1,958 words) - 17:08, 8 June 2024
  • Thumbnail for Pericyte
    S, Cao G, O'Brien-Jenkins A, Randall TC, Rubin SC, Coukos G (June 2003). "Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2...
    40 KB (4,612 words) - 01:45, 27 April 2024
  • Brolucizumab (category Chemicals that do not have a ChemSpider ID assigned)
    was designed to attach to and block a substance called vascular endothelial growth factor A (VEGF-A). VEGF-A is a protein that makes blood vessels grow...
    14 KB (1,121 words) - 07:47, 19 June 2024
  • Thumbnail for POEMS syndrome
    diffusion capacity), very high blood levels of the cytokine vascular endothelial growth factor (VEGF), and an overlap with the signs and symptoms of multicentric...
    25 KB (2,241 words) - 23:44, 14 June 2024
  • Thumbnail for Neuropilin
    Neuropilin (category Protein pages needing a picture)
    and Vascular Endothelial Growth Factor (VEGF) receptors/VEGF ligands, respectively. Neuropilins predominantly act as co-receptors as they have a very...
    11 KB (1,055 words) - 03:34, 23 June 2024
  • Archived from the original on 2008-05-11. Jänne, Pasi A.; Gray, Nathanael; Settleman, Jeff (2009). "Factors underlying sensitivity of cancers to small-molecule...
    23 KB (742 words) - 04:57, 30 December 2023
  • Thumbnail for TGF beta 1
    Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein...
    19 KB (2,290 words) - 20:43, 26 March 2024
  • Ranibizumab (category Chemicals that do not have a ChemSpider ID assigned)
    are known. Ranibizumab is a monoclonal antibody that inhibits angiogenesis by inhibiting vascular endothelial growth factor A, a mechanism similar to that...
    33 KB (2,555 words) - 05:12, 4 June 2024