Anti-double stranded DNA (Anti-dsDNA) antibodies are a group of anti-nuclear antibodies (ANA) the target antigen of which is double stranded DNA. Blood...
23 KB (2,924 words) - 07:24, 20 July 2024
such as anti-Ro antibodies, anti-La antibodies, anti-Sm antibodies, anti-nRNP antibodies, anti-Scl-70 antibodies, anti-dsDNA antibodies, anti-histone...
54 KB (6,097 words) - 21:43, 28 June 2024
detection of anti-dsDNA antibodies, a type of anti-nuclear antibody. Anti-nuclear antibodies are a common feature in SLE, and anti-dsDNA antibodies are highly...
5 KB (552 words) - 17:26, 24 May 2024
Anti-histone antibodies are autoantibodies that are a subset of the anti-nuclear antibody family, which specifically target histone protein subunits or...
6 KB (639 words) - 23:05, 14 September 2023
Lupus (section Anti-nRNP autoimmunity)
antinuclear antibodies include anti-Smith and anti-double stranded DNA (anti-dsDNA) antibodies (which are linked to SLE) and anti-histone antibodies (which...
130 KB (14,247 words) - 21:41, 17 November 2024
They are also referred to as anti-DNA topoisomerase I antibody (anti-topo I). Anti Scl-70 antibodies (also called anti-topoisomerase I after the type...
9 KB (870 words) - 07:54, 22 August 2024
laboratory values such as the anti-nuclear antibody, rheumatoid factor, anti-citrullinated protein antibodies, anti-dsDNA antibodies and other similar connective...
21 KB (2,126 words) - 05:25, 12 August 2024
are consistent with non-specific inflammation. Antinuclear antibodies and anti-dsDNA antibodies may be positive. Biopsies show non specific inflammatory...
4 KB (519 words) - 18:44, 26 September 2021
Omalizumab (redirect from Monoclonal anti-IgE antibodies)
anti-IgE therapeutic antibodies and the pharmacological mechanisms of anti-IgE therapy have been summarized in articles by the inventor of the anti-IgE...
47 KB (4,922 words) - 13:34, 12 November 2024
Thyroglobulin (redirect from Anti-thyroglobulin antibodies)
complicated by the presence of anti-thyroglobulin antibodies (ATAs, alternatively referred to as TgAb). Anti-thyroglobulin antibodies are present in 1 in 10 normal...
17 KB (1,983 words) - 19:38, 30 June 2024
are designed to block specific B-cell anti double stranded DNA antibodies. It may also complex anti dsDNA antibodies together, therefore disabling them....
3 KB (174 words) - 21:49, 22 January 2023
Autoantibody (redirect from Auto-antibodies)
diseases (notably lupus erythematosus) are associated with such antibodies. Antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response...
18 KB (1,555 words) - 19:01, 1 March 2024
immunization-induced antibodies show greater affinity to native epitopes than recombinant protein-induced antibodies. In other words, DNA immunization induces...
77 KB (8,381 words) - 00:49, 24 July 2024
Neuromyelitis optica spectrum disorder (redirect from NMO antibodies)
focused on targeted treatment aimed at anti-aquaporin 4 antibodies. The most established method for antibody removal is plasmapheresis. A number of drugs...
68 KB (7,285 words) - 22:42, 21 September 2024
coupled to an antibody that targets a specific tumor antigen (or protein) that, ideally, is only found in or on tumor cells. Antibodies attach themselves...
41 KB (4,305 words) - 11:56, 24 August 2024
Antiviral drug (redirect from Anti viral)
receptors. This may include VAP anti-idiotypic antibodies, natural ligands of the receptor and anti-receptor antibodies.[clarification needed] Using agents...
55 KB (6,733 words) - 21:23, 24 October 2024
Virus (redirect from Antibodies, viral)
groups: I: dsDNA viruses (e.g. Adenoviruses, Herpesviruses, Poxviruses) II: ssDNA viruses (+ strand or "sense") DNA (e.g. Parvoviruses) III: dsRNA viruses...
155 KB (18,247 words) - 21:39, 28 October 2024
(SLE) through the presence of naturally occurring antibodies. Significant amounts of anti Z-DNA antibodies were found in SLE patients and were not present...
34 KB (4,310 words) - 05:43, 18 September 2024
Henrik (2016-09-20). "Flow-Induced Dispersion Analysis for Probing Anti-dsDNA Antibody Binding Heterogeneity in Systemic Lupus Erythematosus Patients: Toward...
6 KB (626 words) - 03:57, 12 May 2024
Trastuzumab deruxtecan (category Monoclonal antibodies for tumors)
2019). "[Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model". PLOS ONE. 14 (10):...
25 KB (2,086 words) - 02:24, 16 July 2024
Sjögren syndrome (redirect from Anti-La antibodies)
acidosis. Among the complications discussed above, women with anti-Ro/SS-A and anti-La/SS-B antibodies who become pregnant have an increased rate of neonatal...
87 KB (9,219 words) - 01:04, 14 November 2024
(September 2016). "Flow-Induced Dispersion Analysis for Probing Anti-dsDNA Antibody Binding Heterogeneity in Systemic Lupus Erythematosus Patients: Toward...
35 KB (4,515 words) - 07:57, 6 August 2024
table: ANA = antinuclear antibodies, CRP = C-reactive protein, ESR = erythrocyte sedimentation rate, dsDNA = double-stranded DNA, ENA = extractable nuclear...
31 KB (2,437 words) - 19:45, 11 September 2024
Aptamer (section Antibody replacement)
structure of antibodies, which are proteins. This difference can make aptamers a better choice than antibodies for some purposes (see antibody replacement)...
61 KB (6,724 words) - 04:52, 18 November 2024
be a short section of a gene or other DNA element that are used to hybridize a cDNA or cRNA (also called anti-sense RNA) sample (called target) under...
54 KB (5,400 words) - 06:08, 28 October 2024
Ifinatamab deruxtecan (category Antibody-drug conjugates)
(DS-7300) is an experimental anti-cancer treatment developed by Merck and Daiichi Sankyo. It is an antibody–drug conjugate that "consists of an anti-B7-H3...
4 KB (211 words) - 18:55, 9 July 2024
leading to misdiagnosis in some patients. Antinuclear antibodies, antiphospholipid antibodies, anti-dsDNA, and rheumatoid factor are usually negative, and...
11 KB (1,177 words) - 05:40, 23 September 2024
Immunotherapy (redirect from IMiDs)
Flt3L, GM-CSF) and targeting the DCs with antibodies to C-type lectin receptors or agonistic antibodies (e.g., anti-CD40) that are conjugated with antigen...
59 KB (6,137 words) - 22:03, 11 October 2024
Small molecule (redirect from Small molecule anti-genomic therapeutics)
and other biologic medical products). With the exception of therapeutic antibodies, many proteins are degraded if administered orally and most often cannot...
12 KB (1,231 words) - 13:55, 14 March 2024
"Pro-inflammatory S100 proteins are associated with glomerulonephritis and anti-dsDNA antibodies in systemic lupus erythematosus". Lupus. 26 (2): 139–149. doi:10...
14 KB (1,622 words) - 00:18, 16 September 2024