A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors...
59 KB (7,090 words) - 06:49, 30 June 2024
DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication. Discovered by Arthur Kornberg in 1956, it was...
15 KB (1,871 words) - 06:15, 30 May 2024
DNA polymerase III holoenzyme is the primary enzyme complex involved in prokaryotic DNA replication. It was discovered by Thomas Kornberg (son of Arthur...
7 KB (807 words) - 13:43, 10 December 2023
DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-dependent DNA polymerase encoded by the PolB gene. DNA Polymerase II is an...
19 KB (2,328 words) - 05:16, 22 August 2024
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that...
43 KB (5,109 words) - 08:28, 28 October 2024
The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists...
89 KB (11,135 words) - 05:58, 8 November 2024
DNA polymerase delta (DNA Pol δ) is an enzyme complex found in eukaryotes that is involved in DNA replication and repair. The DNA polymerase delta complex...
2 KB (259 words) - 21:21, 11 December 2023
DNA polymerase (DNA-directed DNA polymerase, DdDP) Family A: DNA polymerase I; Pol γ, θ, ν Family B: DNA polymerase II; Pol α, δ, ε, ζ Family C: DNA polymerase...
7 KB (673 words) - 23:08, 9 July 2024
DNA polymerase alpha also known as Pol α is an enzyme complex found in eukaryotes that is involved in initiation of DNA replication. The DNA polymerase...
3 KB (338 words) - 07:55, 4 January 2024
Pfu DNA polymerase is an enzyme found in the hyperthermophilic archaeon Pyrococcus furiosus, where it functions to copy the organism's DNA during cell...
5 KB (449 words) - 16:30, 29 May 2024
Taq polymerase is a thermostable DNA polymerase I named after the thermophilic eubacterial microorganism Thermus aquaticus, from which it was originally...
22 KB (2,608 words) - 16:00, 4 November 2024
Thermostable DNA polymerases are DNA polymerases that originate from thermophiles, usually bacterial or archaeal species, and are therefore thermostable...
41 KB (5,164 words) - 23:57, 28 July 2024
synthesized partner strand. DNA polymerases are a family of enzymes that carry out all forms of DNA replication. DNA polymerases in general cannot initiate...
60 KB (7,286 words) - 00:09, 20 November 2024
Reverse transcriptase (redirect from RNA-directed DNA polymerase)
and DNA-dependent DNA polymerase activity. Collectively, these activities enable the enzyme to convert single-stranded RNA into double-stranded cDNA. In...
27 KB (3,043 words) - 03:16, 30 June 2024
of the DNA polymerase III holoenzyme, the clamp protein binds DNA polymerase and prevents this enzyme from dissociating from the template DNA strand....
23 KB (2,044 words) - 07:04, 10 March 2024
DNA polymerase epsilon is a member of the DNA polymerase family of enzymes found in eukaryotes. It is composed of the following four subunits: POLE (central...
3 KB (336 words) - 09:50, 4 November 2023
genome. DNA replication is the action of DNA polymerases synthesizing a DNA strand complementary to the original template strand. To synthesize DNA, the...
119 KB (14,646 words) - 22:02, 3 July 2024
A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those...
25 KB (2,893 words) - 04:22, 4 July 2023
switching out regular DNA polymerases for specialized translesion polymerases (i.e. DNA polymerase IV or V, from the Y Polymerase family), often with larger...
129 KB (15,900 words) - 22:25, 12 October 2024
primers with the DNA template; the third, at between 68 and 72 °C, facilitates the polymerization carried out by the DNA polymerase. Due to the small...
43 KB (5,346 words) - 03:57, 30 October 2024
binding sites. Polymerase chain reaction itself is the process used to amplify DNA samples, via a temperature-mediated DNA polymerase. The products can...
3 KB (361 words) - 16:20, 23 October 2023
Okazaki fragments (category DNA replication)
helicase, creating what is known as the DNA replication fork. Following this fork, DNA primase and DNA polymerase begin to act in order to create a new...
34 KB (4,470 words) - 07:49, 11 November 2024
DNA polymerase may refer to: DNA polymerase, enzymes that create DNA molecules by assembling nucleotides DNA polymerase I, an enzyme that participates...
1 KB (209 words) - 23:59, 2 April 2016
DNA polymerase beta, also known as POLB, is an enzyme present in eukaryotes. In humans, it is encoded by the POLB gene. In eukaryotic cells, DNA polymerase...
19 KB (2,214 words) - 09:45, 23 December 2023
DNA Polymerase V (Pol V) is a polymerase enzyme involved in DNA repair mechanisms in bacteria, such as Escherichia coli. It is composed of a UmuD' homodimer...
10 KB (1,099 words) - 00:05, 28 June 2024
Exonuclease (section Significance to polymerase)
the polymerase. This process involves the exonuclease's catching up to the pol II and terminating the transcription. Pol I then synthesizes DNA nucleotides...
14 KB (1,752 words) - 22:37, 2 October 2024
Primer (molecular biology) (redirect from DNA primer)
initiation of DNA synthesis. A synthetic primer may also be referred to as an oligo, short for oligonucleotide. DNA polymerase (responsible for DNA replication)...
16 KB (2,112 words) - 01:32, 8 September 2024
Replisome (category DNA replication)
helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase III, RNAse H, and DNA ligase. For prokaryotes, each dividing nucleoid (region containing...
32 KB (3,700 words) - 00:38, 1 January 2024
Transcription (biology) (redirect from DNA transcription)
replication. This process is catalyzed by a viral RNA dependent RNA polymerase. A DNA transcription unit encoding for a protein may contain both a coding...
59 KB (6,894 words) - 20:05, 18 November 2024
DNA polymerase eta (Pol η), is a protein that in humans is encoded by the POLH gene. DNA polymerase eta is a eukaryotic DNA polymerase involved in the...
13 KB (1,548 words) - 23:45, 2 December 2023