The Friedel–Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring....
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Electrophilic aromatic substitution (redirect from Tscherniac–Einhorn reaction)
sulfonation, alkylation Friedel–Crafts reaction and acylation Friedel–Crafts reaction. The most widely practised example of this reaction is the ethylation...
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Aluminium chloride (redirect from Friedel-Crafts catalyst)
as a catalyst in Friedel-Crafts alkylation and related reactions. AlCl3 is a common Lewis-acid catalyst for Friedel-Crafts reactions, both acylations...
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for the German chemist Ludwig Gattermann and is similar to the Friedel–Crafts reaction. Modifications have shown that it is possible to use sodium cyanide...
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Mason Crafts (March 8, 1839 – June 20, 1917) was an American chemist, mostly known for developing the Friedel–Crafts alkylation and acylation reactions with...
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Lewis acid catalysis (category Chemical reactions)
reactions involving carbon–carbon or carbon–heteroatom bond formation can be catalyzed by Lewis acids. Examples include the Friedel-Crafts reaction,...
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1-Tetralone (section By Friedel-Crafts reactions)
3-Benzoylpropanoic acid itself can be obtained by a Haworth reaction (a variant of the Friedel-Crafts reaction) from benzene and succinic anhydride. The intramolecular...
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Acetyl chloride (section Friedel-Crafts acetylations)
ketene. A second major class of acetylation reactions are the Friedel-Crafts reactions. Acetic acid Acetyl bromide Acetyl fluoride Acetyl iodide Merck...
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for the Friedel–Crafts reaction Georges Friedel (1865–1933), French crystallographer and mineralogist; son of Charles Edmond Friedel (1895–1972), French...
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2-tert-butylpyridine. The reaction resembles Friedel-Crafts alkylation but with opposite reactivity and selectivity. The Minisci reaction often produces a mixture...
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Alkylation (category Organic reactions)
Amberlyst, or Lewis acids like aluminium. On a laboratory scale the Friedel–Crafts reaction uses alkyl halides, as these are often easier to handle than their...
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reaction is a special case of a Friedel-Crafts alkylation and was first described by Theodor Zincke and Suhl in 1906. Unlike the traditional Friedel-Crafts...
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One-pot synthesis (redirect from One-pot chemical reaction)
is introduced (red). The enolate reacts as an electrophile in a Friedel-Crafts reaction with ring-closure. The alcohol group is eliminated in presence...
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for the Friedel-Crafts reaction Georges Friedel (1865–1933), French crystallographer and mineralogist; son of Charles Edmond Friedel (1895–1972), French...
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and mineralogy at the Sorbonne. Friedel developed the Friedel-Crafts alkylation and acylation reactions with James Crafts in 1877, and attempted to make...
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Trisoxazolines (section Friedel–Crafts reaction)
Zheng-Zheng; Tang, Yong (1 February 2004). "Controllable Enantioselective Friedel−Crafts Reaction between Indoles and Alkylidene Malonates Catalyzed by Pseudo-C3-Symmetric...
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Dibenzofuran (section Reactions)
transfer agent. It undergoes electrophilic reactions, such as halogenation and Friedel-Crafts reactions. Reaction of DBF with butyl lithium results in dilithiation...
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condensation, the Friedel–Crafts acylation, and the Diels–Alder reaction. Books have been published devoted exclusively to name reactions; the Merck Index...
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Sulfone (section Synthesis and reactions)
resulting sulfolene. Sulfones are prepared under conditions used for Friedel–Crafts reactions using sources of RSO+ 2 derived from sulfonyl halides and sulfonic...
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Triphenylmethane (section Reactions of C-H bond)
(C6H5CHCl2, Benzylenchlorid). Triphenylmethane can be synthesized by Friedel–Crafts reaction from benzene and chloroform with aluminium chloride catalyst: 3...
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Leaving group (category Reaction mechanisms)
in the Friedel-Crafts reaction. Here, a strong Lewis acid is required to generate either a carbocation from an alkyl halide in the Friedel-Crafts alkylation...
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Formylation (redirect from Formylation reaction)
Gattermann reaction and Gattermann-Koch reaction. These involve strong acid catalysis and proceed in a manner similar to the Friedel–Crafts reaction. Hydroformylation...
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Anthraquinone (section Reactions)
oxidant. The Friedel-Crafts reaction of benzene and phthalic anhydride in presence of AlCl3. o-Benzoylbenzoic acid is an intermediate. This reaction is useful...
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Clemmensen reduction (redirect from Clemmensen Reaction)
aryl-alkyl ketones, such as those formed in a Friedel-Crafts acylation. The two-step sequence of Friedel-Crafts acylation followed by Clemmensen reduction...
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for Friedel-Crafts acylations and alkylations, which are often carried out with AlCl3 as the catalyst in an organic solvent. The nature of the Friedel-Craft...
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Synthesis of nucleosides (redirect from Silyl-Hilbert-Johnson reaction)
derivatives used for SHJ reactions should be purified, dried, and powdered before use. Intramolecular Friedel-Crafts reaction of the aromatic ring of a...
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Library. "4.10: Alkylation and Acylation of Aromatic Rings - The Friedel-Crafts Reaction". Chemistry LibreTexts. 2020-06-21. Retrieved 2024-02-07. Wiberg;...
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an arene compound to form an aryl ketone. The reaction is a type of Friedel-Crafts acylation with hydrogen chloride and a Lewis acid catalyst. The synthesis...
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(alcohols and amines) Lewis acids-mediated reactions: Beckmann Reaction, Friedel-Crafts Reaction etc. Reactions using Organometallic reagents or basic agents:...
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POCl3 can be used to remove AlCl3 from reaction mixtures, for example at the end of a Friedel-Crafts reaction. POCl3 reacts with hydrogen bromide in the...
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