• Thumbnail for Gonadotropin-releasing hormone modulator
    luteinizing-releasing hormone, or LHRH). They include GnRH agonists and GnRH antagonists. These medications may be GnRH analogues like leuprorelin and cetrorelix – peptides...
    6 KB (514 words) - 19:52, 27 March 2024
  • Thumbnail for Gonadotropin-releasing hormone agonist
    gonadotropin release, GnRH agonists can lower sex hormone levels by 95% in both sexes. GnRH was discovered in 1971, and GnRH analogues were introduced for...
    24 KB (2,462 words) - 20:32, 3 July 2024
  • Thumbnail for Gonadotropin-releasing hormone
    Gonadotropin-releasing hormone (GnRH) is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone...
    27 KB (3,150 words) - 08:47, 11 April 2024
  • Thumbnail for Goserelin
    Goserelin (category GnRH agonists)
    discontinued.< Goserelin is a synthetic analogue of a naturally occurring gonadotropin-releasing hormone (GnRH). Bioavailability is almost complete by...
    10 KB (799 words) - 21:26, 8 June 2024
  • Thumbnail for Leuprorelin
    Leuprorelin (category GnRH agonists)
    under the skin. Leuprorelin is in the gonadotropin-releasing hormone (GnRH) analogue family of medications. It works by decreasing gonadotropins and therefore...
    41 KB (3,397 words) - 13:20, 9 August 2024
  • Thumbnail for Triptorelin
    Triptorelin (category GnRH agonists)
    Triptorelin is a gonadorelin analogue, also known as luteinizing hormone releasing analogue (GnRH analogue, LHRH analogue). The drug binds to receptors...
    14 KB (981 words) - 11:38, 23 March 2024
  • effectiveness in the treatment of prostate cancer compared to castration and GnRH analogues but a different and potentially superior tolerability and safety profile...
    85 KB (8,742 words) - 03:27, 16 August 2024
  • Thumbnail for Bicalutamide
    It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat metastatic prostate cancer...
    216 KB (21,601 words) - 09:16, 19 July 2024
  • Thumbnail for Gonadorelin
    syndrome), delayed puberty, cryptorchidism, and infertility. Unlike other GnRH analogues, it is not used to suppress sex hormone production. Gonadorelin is available...
    12 KB (814 words) - 16:09, 12 July 2024
  • Thumbnail for Nafarelin
    Nafarelin (category GnRH agonists)
    throughout the world. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being buserelin. Nafarelin...
    23 KB (1,899 words) - 04:25, 10 July 2024
  • bicalutamide, an AR antagonist, with a gonadotropin-releasing hormone (GnRH) analogue such as leuprorelin or cetrorelix. MAB was developed for and is employed...
    3 KB (291 words) - 16:49, 12 August 2023
  • Thumbnail for Ganirelix
    Ganirelix (category GnRH antagonists)
    is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation...
    11 KB (855 words) - 04:14, 1 June 2024
  • Thumbnail for Elagolix
    Elagolix (category GnRH antagonists)
    peptides and first-generation GnRH modulators, elagolix is not a GnRH analogue as it is not structurally related to GnRH. Elagolix was the first second-generation...
    64 KB (6,216 words) - 09:26, 11 May 2024
  • Thumbnail for Antiandrogen
    Combined androgen blockade via flutamide and a GnRH analogue is found to be superior to a GnRH analogue alone for prostate cancer 1989: Flutamide is first...
    158 KB (15,043 words) - 06:11, 3 August 2024
  • Thumbnail for Fertirelin
    Fertirelin (category GnRH agonists)
    of ovarian failure in cattle. Fertirelin is a synthetic peptide and GnRH analogue. It is used as the acetate salt. Gonadotropin-releasing hormone receptor...
    5 KB (216 words) - 10:44, 29 December 2023
  • Thumbnail for Histrelin
    Histrelin (category GnRH agonists)
    Vantas and Supprelin LA among others, is a nonapeptide analogue of gonadotropin-releasing hormone (GnRH) with added potency. When present in the bloodstream...
    10 KB (798 words) - 04:07, 17 August 2024
  • Thumbnail for Buserelin
    Buserelin (category GnRH agonists)
    many other countries. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being nafarelin. Buserelin...
    35 KB (3,024 words) - 21:35, 10 March 2024
  • Thumbnail for Gonadotropin-releasing hormone antagonist
    hormone antagonists (GnRH antagonists) are a class of medications that antagonize the gonadotropin-releasing hormone receptor (GnRH receptor) and thus the...
    19 KB (1,923 words) - 00:57, 21 March 2024
  • for FTM therapy include, mainly, androgens (namely testosterone) and GnRH analogues. While the therapy cannot undo the effects of a person's first puberty...
    59 KB (7,731 words) - 20:31, 8 May 2024
  • Thumbnail for Azagly-nafarelin
    Azagly-nafarelin (category GnRH agonists)
    gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in veterinary medicine in Europe. It is a GnRH analogue and a synthetic peptide, specifically...
    8 KB (465 words) - 21:07, 28 April 2024
  • castration. GnRH modulators are also commonly known as GnRH analogues. However, not all clinically used GnRH modulators are analogues of GnRH. There are...
    231 KB (25,191 words) - 20:09, 15 August 2024
  • Thumbnail for Acyline
    Acyline (category GnRH antagonists)
    is a gonadotropin-releasing hormone analogue (GnRH analogue) and gonadotropin-releasing hormone antagonist (GnRH antagonist) which was never marketed...
    5 KB (224 words) - 06:11, 26 February 2024
  • Thumbnail for Flutamide
    Normally administered are GnRH analogues, such as leuprorelin or cetrorelix. Although GnRH agonists stimulate the same receptors that GnRH does, since they are...
    99 KB (10,959 words) - 06:32, 12 May 2024
  • Thumbnail for Cetrorelix
    Cetrorelix (category GnRH antagonists)
    the brand name Cetrotide, is an injectable gonadotropin-releasing hormone (GnRH) antagonist. A synthetic decapeptide, it is used in assisted reproduction...
    10 KB (785 words) - 19:52, 20 December 2023
  • Thumbnail for Degarelix
    Degarelix (category GnRH antagonists)
    to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocking their interaction with GnRH. This induces a fast and profound reduction...
    15 KB (1,179 words) - 23:11, 26 January 2024
  • Thumbnail for Lecirelin
    Lecirelin (category GnRH agonists)
    gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in veterinary medicine in Europe and Israel. It is a GnRH analogue and a synthetic peptide...
    5 KB (195 words) - 06:15, 27 August 2023
  • Thumbnail for Deslorelin
    Deslorelin (category GnRH agonists)
    almost complete. Deslorelin is a synthetic analogue of naturally occurring gonadotropin-releasing hormone (GnRH). Deslorelin was successfully trialed in...
    10 KB (676 words) - 05:46, 1 July 2024
  • Thumbnail for Peforelin
    Peforelin (category GnRH agonists)
    gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in veterinary medicine in Europe and Canada. It is a GnRH analogue and a synthetic peptide...
    4 KB (141 words) - 01:25, 1 October 2023
  • Thumbnail for Dutasteride
    comparing the addition of bicalutamide with or without dutasteride to GnRH analogue therapy in men with non-metastatic castrate-resistant prostate cancer"...
    51 KB (4,969 words) - 08:21, 27 July 2024
  • Thumbnail for 5α-Reductase inhibitor
    comparing the addition of bicalutamide with or without dutasteride to GnRH analogue therapy in men with non-metastatic castrate-resistant prostate cancer"...
    31 KB (3,433 words) - 01:04, 23 June 2024