• Thumbnail for Graft-versus-host disease
    Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants...
    39 KB (4,442 words) - 15:41, 17 October 2024
  • Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of blood transfusion, in which the immunologically competent donor T...
    7 KB (693 words) - 07:37, 19 August 2023
  • Thumbnail for Hematopoietic stem cell transplantation
    radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT. HSCT remains a dangerous...
    73 KB (8,333 words) - 21:39, 14 November 2024
  • acute graft versus host disease in recipients receiving progenitor cell transplants. While higher doses (15 mg/kg) reduced acute graft versus host this...
    8 KB (895 words) - 14:10, 23 August 2023
  • Thumbnail for Transplant rejection
    mediate allograft rejection via the CD4 and CD8 T cells. Graft-versus-host disease Graft-versus-tumor effect Immunosuppression Transplant engineering Frohn...
    29 KB (3,272 words) - 23:54, 28 May 2024
  • myeloma and possibly breast cancer. It is closely linked with graft-versus-host disease (GvHD), as the underlying principle of alloimmunity is the same...
    9 KB (1,116 words) - 17:21, 7 November 2023
  • transplant can result in an immune attack on the recipient, called graft-versus-host disease. Material is obtained from a donor who is a living person, or...
    7 KB (688 words) - 18:14, 10 November 2024
  • Thumbnail for Cyclophosphamide
    people who are ill-suited for autologous stem cell transplant. Graft-versus-host disease (GVHD) is a major barrier for allogeneic stem cell transplant...
    39 KB (3,990 words) - 18:36, 16 October 2024
  • Thumbnail for Sirolimus
    DA (June 1998). "Rapamycin inhibits the generation of graft-versus-host disease- and graft-versus-leukemia-causing T cells by interfering with the production...
    70 KB (7,051 words) - 03:41, 9 November 2024
  • Thumbnail for Lichen planus
    lichenoid reactions. They can also occur in association with graft versus host disease.: 258  Lichen planus lesions are so called because of their "lichen-like"...
    63 KB (7,080 words) - 01:53, 14 November 2024
  • Thumbnail for Alemtuzumab
    (no controls) with severe steroid-resistant acute intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation (HSCT)...
    19 KB (1,903 words) - 02:49, 24 August 2024
  • involved the detrimental effects of renal fibrosis.[citation needed] Graft-versus-host disease (GvHD) targets JAK 1 and 2, the human tyrosine kinase protein...
    20 KB (2,259 words) - 08:57, 2 November 2024
  • Thumbnail for Ruxolitinib
    to or intolerance of hydroxyurea; and steroid-refractory acute graft-versus-host disease. Ruxolitinib is a Janus kinase inhibitor. It was developed and...
    26 KB (2,155 words) - 19:16, 30 October 2024
  • Niktimvo, is a monoclonal antibody used for the treatment of chronic graft-versus-host disease. It is a blocker of the colony stimulating factor-1 receptor....
    6 KB (318 words) - 21:44, 11 November 2024
  • Thumbnail for Non-Hodgkin lymphoma
    participants receive stem-cell transplants, they can develop a graft-versus-host disease. When compared with placebo for treating immune mediated inflammation...
    33 KB (3,216 words) - 01:48, 14 November 2024
  • Thumbnail for Lymphoma
    of graft-versus-host diseases. The evidence is very uncertain about the therapeutic effect of mesenchymal stromal cells to treat graft-versus-host diseases...
    67 KB (6,603 words) - 19:22, 22 November 2024
  • group A streptococcus, and non-infectious conditions such as graft-versus-host disease. The viruses can invade lung epithelial cells and alveolar macrophages...
    25 KB (2,786 words) - 02:05, 24 June 2024
  • therapeutics. LPAM-1 integrin is involved in the development of graft-versus-host disease (GVHD). Donor-derived CTL cells use α4β7 integrin to migrate to...
    9 KB (1,246 words) - 04:54, 14 November 2024
  • Thumbnail for Belumosudil
    among others, is a medication used for the treatment of chronic graft versus host disease (cGvHD). It is in the class of drugs known as serine/threonine...
    15 KB (1,110 words) - 03:14, 18 September 2024
  • Thumbnail for Purinergic signalling
    in patients with Graft-versus-host disease (GVHD), ATP is released into the peritoneal fluid. It binds onto the P2RX7 receptors of host antigen-presenting...
    54 KB (5,956 words) - 10:13, 12 August 2024
  • Thumbnail for Immunosuppression
    it is used for treating graft-versus-host disease after a bone marrow transplant, or for the treatment of auto-immune diseases such as systemic lupus erythematosus...
    10 KB (938 words) - 16:41, 3 December 2023
  • Thumbnail for Eosinophilia
    fungi and viruses. They also participate in transplant rejection, Graft-versus-host disease, and the killing of tumor cells. In conducting these functions...
    50 KB (5,523 words) - 06:20, 11 November 2024
  • Thumbnail for Thalidomide
    medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy such...
    76 KB (7,432 words) - 14:59, 21 November 2024
  • Thumbnail for Multiple myeloma
    multiple myeloma. Stem cell transplants come with a risk of a graft-versus-host-disease. Mesenchymal stromal cells may reduce the all-cause mortality...
    131 KB (13,509 words) - 07:49, 11 November 2024
  • Theoretically, thymus transplantation could cause two types of graft-versus-host disease (GVHD): First, it could cause a donor T cell-related GVHD, because...
    7 KB (878 words) - 10:58, 19 April 2024
  • Thumbnail for Maculopapular rash
    may also have this appearance. Maculopapular rash is seen in graft-versus-host disease (GVHD) developed after a hematopoietic stem cell transplant (bone...
    4 KB (489 words) - 17:52, 8 September 2024
  • lymphoma. Evidence suggests that this treatment might help treat graft-versus-host disease, though this evidence is largely observational; controlled trials...
    7 KB (576 words) - 19:39, 25 May 2024
  • Thumbnail for Hurler syndrome
    cognitive function, and physical symptoms. Patients can develop graft versus host disease; this is more likely in non-sibling donors. In a 1998 study, children...
    16 KB (1,783 words) - 18:12, 29 October 2024
  • Thumbnail for HLA-DR
    HLA-DR (category Human MHC mediated diseases)
    were originally defined as cell surface antigens that mediate graft-versus-host disease. Identification of these antigens has led to greater success and...
    31 KB (2,293 words) - 12:25, 28 December 2023
  • Thumbnail for Pimicotinib
    investigated as a treatment for tenosynovial giant cell tumor, chronic graft-versus-host-disease (cGVHD), and pancreatic cancer. Vaynrub A, Healey JH, Tap W, Vaynrub...
    6 KB (486 words) - 16:05, 19 September 2024