The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members...
34 KB (3,629 words) - 17:37, 18 March 2024
Metabotropic glutamate receptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene. mGluR2 is a G protein-coupled receptor (GPCR) that...
22 KB (2,647 words) - 08:11, 10 March 2024
The glutamate receptor, metabotropic 1, also known as GRM1, is a human gene which encodes the metabotropic glutamate receptor 1 (mGluR1) protein. L-Glutamate...
22 KB (2,342 words) - 22:25, 20 September 2024
Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of...
16 KB (1,704 words) - 05:36, 17 August 2024
Metabotropic glutamate receptor 5 is an excitatory Gq-coupled G protein-coupled receptor predominantly expressed on the postsynaptic sites of neurons....
28 KB (3,032 words) - 17:40, 2 October 2024
Metabotropic glutamate receptor 3 (mGluR3) is an inhibitory Gi/G0-coupled G-protein coupled receptor (GPCR) generally localized to presynaptic sites of...
28 KB (3,074 words) - 08:11, 10 March 2024
Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base...
63 KB (6,876 words) - 17:09, 12 September 2024
Metabotropic glutamate receptor 8 is a protein that in humans is encoded by the GRM8 gene. L-glutamate is the major excitatory neurotransmitter in the...
6 KB (708 words) - 16:57, 28 November 2023
Metabotropic glutamate receptor 7 is a protein that in humans is encoded by the GRM7 gene. L-glutamate is the major excitatory neurotransmitter in the...
12 KB (1,359 words) - 23:10, 4 April 2024
Glutamate receptor, metabotropic 6, also known as GRM6 or mGluR6, is a protein which in humans is encoded by the GRM6 gene. L-glutamate is the major excitatory...
7 KB (868 words) - 09:00, 18 August 2023
Biochemical receptors for glutamate fall into three major classes, known as AMPA receptors, NMDA receptors, and metabotropic glutamate receptors. A fourth...
20 KB (2,177 words) - 11:44, 17 August 2024
A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic...
6 KB (625 words) - 00:59, 6 June 2024
Glutamic acid (redirect from Glutamate)
and metabotropic (G-protein coupled) receptors. In the opposing postsynaptic cell, glutamate receptors, such as the NMDA receptor or the AMPA receptor, bind...
35 KB (3,237 words) - 17:07, 11 September 2024
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate. They mediate the majority...
5 KB (433 words) - 06:16, 15 October 2023
N-methyl-D-aspartate (NMDA) type glutamate ion channel receptor; the second posits that the taste is transduced by a metabotropic type glutamate receptor (taste-mGluR4)...
36 KB (3,927 words) - 15:59, 5 October 2024
Ibotenic acid (category AMPA receptor agonists)
mGluR3) metabotropic glutamate receptors. It is inactive at group III mGluRs. Ibotenic acid also acts as a weak agonist of the AMPA and kainate receptors. In...
16 KB (1,473 words) - 00:34, 20 July 2024
message (i.e. metabotropic receptors do not have channels). There are several kinds of metabotropic receptors, including G protein-coupled receptors. Ionotropic...
16 KB (1,590 words) - 01:49, 26 October 2023
acetylcholine receptors and within C1 by the activation of group I metabotropic glutamate receptors. When interneurons are activated by metabotropic acetylcholine...
22 KB (2,705 words) - 08:12, 8 January 2024
candidate umami taste receptors include splice variants of metabotropic glutamate receptors, mGluR4 and mGluR1, and the NMDA receptor. During the evolution...
42 KB (4,345 words) - 04:01, 9 September 2024
Umami (section Taste receptors)
taste receptors that typically respond to glutamates and nucleotides, which are widely present in meat broths and fermented products. Glutamates are commonly...
35 KB (3,767 words) - 22:08, 30 September 2024
receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons. The NMDA receptor is...
107 KB (12,058 words) - 22:07, 12 October 2024
mGluR6Tooltip Metabotropic glutamate receptor 6 Agonists: Glutamate L-AP4 Antagonists: CPPG MAP4 MPPG MSOP MTPG UBP-1112 mGluR7Tooltip Metabotropic glutamate receptor...
47 KB (5,008 words) - 19:20, 15 October 2024
Kainate receptors, or kainic acid receptors (KARs), are ionotropic receptors that respond to the neurotransmitter glutamate. They were first identified...
11 KB (1,263 words) - 21:34, 11 June 2024
Kainic acid (category Kainate receptor agonists)
classifications of glutamate receptors: NMDA receptors, AMPA receptors, kainate receptors, and the metabotropic glutamate receptors. Kainic acid is an...
11 KB (1,117 words) - 10:58, 18 October 2023
Quisqualic acid (category AMPA receptor agonists)
agonist of the AMPA, kainate, and group I metabotropic glutamate receptors. It is one of the most potent AMPA receptor agonists known. It causes excitotoxicity...
31 KB (3,541 words) - 16:24, 7 October 2024
Group II metabotropic glutamate receptors in humans. It is also known to be a potent VGLUT inhibitor, thereby preventing the movement of glutamate from the...
6 KB (427 words) - 07:04, 8 September 2023
LY-341495 (category MGlu2 receptor antagonists)
potent and selective orthosteric antagonist for the group II metabotropic glutamate receptors (mGluR2/3). It is used in scientific research in several different...
11 KB (1,011 words) - 19:32, 20 December 2023
mGluR6Tooltip Metabotropic glutamate receptor 6 Agonists: Glutamate L-AP4 Antagonists: CPPG MAP4 MPPG MSOP MTPG UBP-1112 mGluR7Tooltip Metabotropic glutamate receptor...
70 KB (7,823 words) - 13:14, 17 October 2024
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked...
16 KB (1,564 words) - 20:19, 25 March 2024
acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate (iGluR) and predominantly...
60 KB (7,024 words) - 22:23, 19 October 2024