Microglia are a type of glial cell located throughout the brain and spinal cord of the central nervous system (CNS). Microglia account for about 10–15%...

Microglia are the primary immune cells of the central nervous system, similar to peripheral macrophages. They respond to pathogens and injury by changing...

hypertrophy of several different types of glial cells, including astrocytes, microglia, and oligodendrocytes. In its most extreme form, the proliferation associated...

oligodendrocytes (that produce myelin), astrocytes, ependymal cells and microglia, and in the peripheral nervous system they include Schwann cells (that...

at Boston Children’s Hospital. She has helped to identify the role of microglia and complement proteins in the "pruning" or removal of synaptic cells...

these extrinsic cues for microglia and microglia themselves may produce proteins that amplify the response. The effect of microglia on neurons that leads...

productive cytotoxic effector cells that are capable of lysing tumor cells Microglia, a glial effector cell that reconstructs the Central nervous system after...

the central nervous system (CNS), including the brain and spinal cord, microglia are the resident innate immune cells that are activated in response to...

ATP has been shown to be a critically important signalling molecule for microglia - neuron interactions in the adult brain, as well as during brain development...

such as monocytes, macrophages, osteoclasts, myeloid dendritic cells, microglia, and Paneth cells. CSF1R expression is controlled by two alternative promoters...

have also been linked to allodynia. For example, there are reports that microglia in the thalamus might contribute to allodynia by changing the properties...

pancreatic stellate cells, dendritic cells, oligodendrocytes, and others. Microglia, which are notably smaller than macroglia, can also extend their end-processes...

causes of a cytokine storm. The cells of the central nervous system, the microglia, neurons, and astrocytes, are also involved in the release of pro-inflammatory...

expression of glial and immune cells in the brain, e.g. astrocytes and microglia, respectively, are overexpressed, which correlates with increased number...

healthy controls, suggesting upregulated microglia-induced synaptic pruning in these individuals. Microglia-mediated synaptic pruning has also been observed...

mechanisms of cellular plasticity and their role in the regulation of microglia-neuron interactions. Her research is aimed at understanding the mechanisms...

–astrocytes, ependymal cells, and oligodendrocytes, and much smaller microglia which are the macrophages of the central nervous system. Astrocytes are...

matter of the brain. Degenerative neuronal elements and an abundance of microglia and astrocytes can be associated with amyloid plaques. Some plaques occur...

disorders. Within the brain, quinolinic acid is only produced by activated microglia and macrophages. In 1949 L. Henderson was one of the earliest to describe...

function. Neuroglial cells are classified as follows: Microglial cells: Microglia are macrophage cells that make up the primary immune system for the CNS...

generally secrete more inhibitory molecules into the extracellular matrix. Microglia are the second most prominent cell type present within the glial scar...

macrophages, immature monocyte-derived dendritic cells, osteoclasts, and microglia, which are immune cells in the central nervous system. In the liver, TREM2...

circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia). Human CD68 is a Type I transmembrane glycoprotein, heavily glycosylated...

sarcopenia, and aging-associated diseases. Senescent astrocytes and microglia contribute to neurodegeneration. Mechanistically, replicative senescence...

often migrate to local lymph nodes upon ingesting antigens) Mast cells Microglia The two commonly used categories of white blood cell disorders divide...

abnormal increase in astrocytes and activation of the brain's immune cells, microglia. The basal ganglia play a key role in movement and behavior control. Their...

3D animation of Müller cell processes (red) interconnected with a retinal microglia cell (green)....

anti-inflammatory states, microglia have also been shown to be able to assist in remyelination & subsequent neuron repair. As such, microglia are thought to be...

by activated microglia. In a murine model of JE, it was found that in the hippocampus and the striatum, the number of activated microglia was more than...

explores the diversity of microglia that exist within the basal ganglia circuitry to one day target regional or circuit-specific microglia in disease. De Biase's...