Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...
37 KB (4,011 words) - 23:48, 17 December 2024
Monoamine oxidases (MAO) (EC 1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group...
39 KB (4,124 words) - 11:34, 2 November 2024
Monoamine oxidase B (MAO-B) is an enzyme that in humans is encoded by the MAOB gene. The protein encoded by this gene belongs to the flavin monoamine...
37 KB (4,431 words) - 19:04, 30 September 2024
Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring...
40 KB (4,637 words) - 01:01, 4 November 2024
Selegiline (category Monoamine oxidase inhibitors)
notably an irreversible monoamine oxidase (MAO) inhibitor (MAOI). More specifically, it is a selective inhibitor of monoamine oxidase B (MAO-B) at lower doses...
208 KB (20,188 words) - 07:28, 1 January 2025
Phenelzine (category Monoamine oxidase inhibitors)
name Nardil among others, is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine family which is primarily used as an...
29 KB (2,796 words) - 13:59, 19 December 2024
Rasagiline (category Monoamine oxidase inhibitors)
an inhibitor of the enzyme monoamine oxidase (MAO) and hence is a monoamine oxidase inhibitor (MAOI). More specifically, it is a selective inhibitor of...
91 KB (8,979 words) - 08:35, 22 December 2024
Tranylcypromine (category Monoamine oxidase inhibitors)
is a monoamine oxidase inhibitor (MAOI). More specifically, tranylcypromine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase...
27 KB (2,535 words) - 06:17, 2 September 2024
Moclobemide (category Monoamine oxidase inhibitors)
Clobemix, Depnil and Manerix among others, is a reversible inhibitor of monoamine oxidase A (RIMA) drug primarily used to treat depression and social...
83 KB (9,147 words) - 02:16, 10 December 2024
selective serotonin reuptake inhibitor (SSRI), serotonin norepinephrine reuptake inhibitor (SNRI), monoamine oxidase inhibitor (MAOI), tricyclic antidepressants...
53 KB (5,344 words) - 07:33, 25 December 2024
orally unless it is combined with a monoamine oxidase inhibitor such as a reversible inhibitor of monoamine oxidase A (RIMA), for example, harmaline. Without...
159 KB (15,313 words) - 03:08, 20 December 2024
Furazolidone (category Monoamine oxidase inhibitors)
Furazolidone is a nitrofuran antibacterial agent and monoamine oxidase inhibitor (MAOI). It is marketed by Roberts Laboratories under the brand name Furoxone...
8 KB (574 words) - 12:48, 18 September 2024
Mirtazapine (category CYP2D6 inhibitors)
may occur with stopping. It is not recommended together with a monoamine oxidase inhibitor, although evidence supporting the danger of this combination...
88 KB (7,948 words) - 07:03, 7 December 2024
Anxiolytic (section Monoamine oxidase inhibitors)
advantage of less sedating and withdrawal effects. The first monoamine oxidase inhibitor (MAOI), iproniazid, was discovered accidentally when developing...
46 KB (4,442 words) - 19:54, 1 December 2024
Α-Methyltryptamine (category Monoamine oxidase inhibitors)
as a reversible inhibitor of the enzyme monoamine oxidase (MAO) in-vitro and in-vivo. In rats, the potency of αMT as an MAO-A inhibitor in the brain was...
44 KB (3,832 words) - 13:13, 8 December 2024
a monoamine oxidase (MAO) inhibitor. It is a selective inhibitor of monoamine oxidase B (MAO-B) at lower doses but additionally inhibits monoamine oxidase...
139 KB (14,124 words) - 07:48, 1 January 2025
antidepressants, such as tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs), as the drugs of choice for the treatment of MDD due...
83 KB (8,171 words) - 00:46, 10 December 2024
Monoamine reuptake inhibitor Monoamine receptor Monoamine oxidase Monoamine transporter Monoamine Hypothesis Biogenic amine Trace amine Monoamine nuclei...
7 KB (1,409 words) - 21:17, 11 March 2024
Harmala alkaloid (category Monoamine oxidase inhibitors)
Harmala alkaloids are several alkaloids that act as monoamine oxidase inhibitors (MAOIs). These alkaloids are found in the seeds of Peganum harmala (also...
14 KB (1,526 words) - 03:35, 8 September 2024
Harmine (category Monoamine oxidase inhibitors)
reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a Reversible inhibitor of monoamine oxidase A (RIMA)...
21 KB (2,132 words) - 03:11, 18 November 2024
Pargyline (category Monoamine oxidase inhibitors)
Pargyline, sold under the brand name Eutonyl among others, is a monoamine oxidase inhibitor (MAOI) medication which has been used to treat hypertension (high...
43 KB (4,057 words) - 00:51, 20 October 2024
Antidepressant (section Monoamine oxidase inhibitors)
effects, a different type of MAOI, the class of reversible inhibitor of monoamine oxidase A (RIMA), has been developed. The primary advantage of RIMAs...
193 KB (20,783 words) - 03:20, 2 December 2024
Tyramine (category Monoamine oxidase inhibitors)
of monoamine oxidase inhibitors (MAOIs). Tyramine occurs widely in plants and animals, and is metabolized by various enzymes, including monoamine oxidases...
29 KB (2,685 words) - 23:57, 2 December 2024
Phenethylamine (category VMAT inhibitors)
can be increased 1000-fold when taking a monoamine oxidase inhibitor (MAOI), particularly a MAO-B inhibitor, and by 3–4 times when the initial concentration...
54 KB (5,178 words) - 18:43, 13 December 2024
Isocarboxazid (category Monoamine oxidase inhibitors)
(Marplan, Marplon, Enerzer) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class used as an antidepressant. Along...
7 KB (555 words) - 18:46, 23 August 2024
syndrome. Taking monoamine oxidase inhibitors (MAOIs) in combination with SSRIs can be fatal, since MAOIs disrupt monoamine oxidase, an enzyme which is...
145 KB (15,410 words) - 18:28, 31 December 2024
(/ˈtʃɑːŋɡɑː/) is a blend of N,N-Dimethyltryptamine (DMT) mixed with a monoamine oxidase inhibitor (MAOI). The addition of MAOIs extends the DMT experience in duration...
5 KB (558 words) - 19:40, 10 December 2024
Pheniprazine (category Monoamine oxidase inhibitors)
names Catron and Cavodil, is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine group that was used as an antidepressant...
9 KB (711 words) - 22:06, 12 August 2024
Α-Ethyltryptamine (category Monoamine oxidase inhibitors)
receptors. αET is a weak monoamine oxidase inhibitor (MAOI). It is specifically a selective and reversible inhibitor of monoamine oxidase A (MAO-A). An IC50Tooltip...
31 KB (2,523 words) - 01:17, 14 November 2024
Sertraline (category CYP2D6 inhibitors)
the age of 25 years old. It should not be used together with monoamine oxidase inhibitors (MAOIs): this combination may cause serotonin syndrome, which...
103 KB (10,564 words) - 01:05, 31 December 2024