The TIM barrel (triose-phosphate isomerase), also known as an alpha/beta barrel,: 252  is a conserved protein fold consisting of eight alpha helices (α-helices)...

Barrel Man, real name Tim McKernan (September 5, 1940 – December 5, 2009), was a superfan of the Denver Broncos. In all types of weather for 30 years...

Look up Tim, tim, or TIM in Wiktionary, the free dictionary. Tim or TIM may refer to: Timothy (given name) Tim (given name) Timmy Timo Timotheus Tim, Denmark...

and Barrel was voiced by Danny Elfman. In the Kingdom Hearts series, Lock was voiced by Jess Harnell, Shock was voiced by Kath Soucie, and Barrel was...

In protein structures, a beta barrel (β barrel) is a beta sheet (β sheet) composed of tandem repeats that twists and coils to form a closed toroidal structure...

or the immunoglobulin fold) or they can be closed β-barrels (such as the TIM barrel). β-Barrels are often described by their stagger or shear. Some open...

parallel to the barrel and the α-helix is in the outside of the barrel but does not contact the α-helices of the other repeats like in TIM barrels. The protein...

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— tryptophan synthase family Fold Type III — alanine racemase family (TIM-barrel) Fold Type IV — D-amino acid aminotransferase family Fold Type V — glycogen...

while another suggests that a stable TIM-barrel structure has evolved through convergent evolution. The TIM-barrel in pyruvate kinase is 'discontinuous'...

notable structural formations, including a type of β-barrel known as a jelly roll barrel and a TIM barrel. Human β-glucuronidase is homologous to the Escherichia...

families Clans of glycoside hydrolases Hierarchical classification of the TIM-barrel type glycoside hydrolases Bourne, Yves; Henrissat, Bernard (2001). "Glycoside...

αβ-barrel, or a TIM-barrel, and is by far the most commonly observed protein fold. The active site of this enzyme is in the center of the barrel. A glutamic...

proteins of diverse function and diverse evolution. For example, the TIM barrel, named for the enzyme triosephosphateisomerase, is a common tertiary structure...

protein subunits of both classes each have an α/β domain folded into a TIM barrel containing the active site. Several subunits are assembled into the complete...

eight alpha/beta barrels that create an active site holding two divalent magnesium ions. Xylose isomerase enzymes exhibit a TIM barrel fold with the active...

site of the enzyme. The catalytic domain of Beta-galactosidases have a TIM barrel core surrounded several other largely beta domains. The sugar binding...

triosephosphate isomerase (TIM) barrel, pleckstrin homology (PH) domain, four tandem EF hand domains, and a C2 domain. The TIM barrel contains the active site...

Tim Simenon – production, mixing Q. – mixing, engineering Kerry Hopwood – programming Mike Marsh – mastering DiGravina, Tim. "Depeche Mode - Barrel of...

These enzymes are involved in purine metabolism. These enzymes adopt a TIM barrel structure. Whitby FG, Luecke H, Kuhn P, Somoza JR, Huete-Perez JA, Phillips...

patch. Barrel tries to stop Jack by forcing him to navigate the maze he had created in the pumpkin patch, but Jack makes it through and defeats Barrel and...

The Nightmare Before Christmas (also known as Tim Burton's The Nightmare Before Christmas) is a 1993 American stop-motion animated musical fantasy film...

consists of two TIM-barrel domains that bind homocysteine and N5-MeTHF individually. The two domains adopt a face-to-face double barrel architecture, which...

the N-terminal domain has an alpha-beta fold, the central domain has a TIM barrel fold, and the C-terminal domain has an all alpha helical fold....

cysteine proteases by disrupting their structure. TIM barrel superfamily Members share a large α8β8 barrel structure. It is one of the most common protein...

the structure. Each domain I comprises a (β/α)8 - barrel structural fold, also known as a TIM barrel, and contains an active site of the enzyme. Each active...

antiparallel helical bundle that plugs the C terminus of the N-terminal TIM barrel domain. The communication domain is thought to play an important role...

bilayers irreversibly and can form transmembrane alpha-helical or beta-barrel channels. Such transformations occur in pore forming toxins such as colicin...

1-60 and residues 91-358, which fold into a β/α structure of a typical TIM barrel. The loop β4 contains two highly conserved residues Asp183 and Glu184...

immunoglobulin fold. Domain III (residues 76–381 and 416–430) is homologous to a TIM barrel and is a highly conserved domain among glycoside hydrolases. Domain III...