The idea was coined by Douglas Hanahan and Robert Weinberg in their paper "The Hallmarks of Cancer" published January 2000 in Cell. These hallmarks constitute...
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Metastasis (redirect from Metastatic cancer)
metastatic potential. Metastasis is one of the hallmarks of cancer, distinguishing it from benign tumors. Most cancers can metastasize, although in varying...
42 KB (5,078 words) - 13:14, 8 November 2024
of the hallmarks of cancer (see below), will have a competitive advantage over cells that have not acquired the hallmark. Thus, at the level of the cell...
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Douglas Hanahan (category Members of the National Academy of Medicine)
entitled "Hallmarks of cancer: the next generation". In 2022, Professor Hanahan published another updated review article, entitled "Hallmarks of Cancer: New...
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the six hallmarks of cancer. These characteristics are required to produce a malignant tumor. They include: Cell growth and division absent the proper...
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metastasis are fundamental hallmarks of cancer, representing the ability of the cancer cells to spread from their site of origin to distant tissues and...
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Anaphase lag (section Hallmark of cancer)
implications in the development and persistence of cancers as well as debilitating developmental diseases. One of the hallmarks of cancer formation and...
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further hallmarks or underlying mechanisms that drive multiple of these hallmarks.[citation needed] Each hallmark was chosen to try to fulfill the following...
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Chemotherapy (redirect from Side effects of cancer treatment)
PMID 19104514. S2CID 17934366. Hanahan D, Weinberg RA (January 2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931...
155 KB (17,519 words) - 02:42, 7 December 2024
Robert Weinberg (biologist) (category Members of the United States National Academy of Sciences)
hard to identify the principles that cancers had in common. He and Douglas Hanahan wrote the seminal paper "The Hallmarks of Cancer", published in January...
17 KB (1,334 words) - 11:47, 5 December 2024
PMID 31399389. Pavlova, NN; Thompson, CB (12 January 2016). "The Emerging Hallmarks of Cancer Metabolism". Cell Metabolism. 23 (1): 27–47. doi:10.1016/j...
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Contact inhibition (section Role in cancer)
PMID 6049107. S2CID 4150783. Hanahan, D.; Weinberg, R. (7 January 2000). "The Hallmarks of Cancer" (PDF). Cell. 100 (1): 57–70. doi:10.1016/s0092-8674(00)81683-9...
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hallmarks of cancer; however, hair follicle cells also grow and divide quickly. Consequently, the chemotherapy drugs usually inhibit hair growth. The...
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Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in...
90 KB (9,784 words) - 12:48, 29 November 2024
Robert Weinberg publish "The Hallmarks of Cancer". January 31 – English doctor Harold Shipman is found guilty of killing fifteen of his elderly patients by...
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influential research reports include: The Hallmarks of Cancer, published in 2000, and Hallmarks of Cancer: The Next Generation, published in 2011, by...
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(1974–1999) The Hallmarks of Cancer "About Cell". Reed Elsevier. Archived from the original on 2010-03-23. Elsevier: Cell: Home Archived 2012-09-25 at the Wayback...
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Glycolysis (section Cancer)
Schwartz L, Supuran CT, Alfarouk KO (2017). "The Warburg Effect and the Hallmarks of Cancer". Anti-Cancer Agents in Medicinal Chemistry. 17 (2): 164–170...
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Aerobic fermentation (redirect from Evolution of aerobic fermentation)
use of acetic acid bacteria to produce vinegar. One of the hallmarks of cancer is altered metabolism or deregulating cellular energetics. Cancers cells...
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Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA...
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Cyclooxygenase-2 inhibitor (redirect from Selective inhibitor of cyclooxygenase 2)
Paraskeva C, Kaidi A (March 2009). "The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment". Carcinogenesis...
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Vasculogenic mimicry (category Cancer)
develop and harness nearby vasculature is considered one of the hallmarks of cancer disease development and is thought to be closely linked to tumor...
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Carcinogenesis (redirect from Cancer induction)
S2CID 38445059. Hanahan, Douglas; Weinberg, Robert A (7 January 2000). "The Hallmarks of Cancer". Cell. 100 (1): 57–70. doi:10.1016/s0092-8674(00)81683-9. ISSN 0092-8674...
115 KB (13,967 words) - 21:47, 4 December 2024
Human papillomavirus infection (category Infectious causes of cancer)
S2CID 71143679. Hanahan, Douglas; Weinberg, Robert A. (7 January 2000). "The Hallmarks of Cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. ISSN 0092-8674...
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one of the hallmarks of cancer. High amount of aerobic glycolysis (also known as the Warburg effect) distinguishes cancer cells from normal cells. The conversion...
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Naked mole-rat (redirect from Longevity of naked mole rats)
does. The combination of p16 and p27 in naked mole-rat cells is a double barrier to uncontrolled cell proliferation, one of the hallmarks of cancer. In...
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Follicular dendritic cell sarcoma (category Rare cancers)
mitotic spindle, during cell division. This contributes to many of the hallmarks of cancer, including proliferative signaling, growth activation, and replicative...
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(dividing cells) the pathologist sees in 10x high power microscope field. One of the hallmarks of cancer is that cells divide uncontrollably. The more cells...
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DNA replication (redirect from Amplification of DNA)
to cancer formation. Increased telomerase activity is one of the hallmarks of cancer.[citation needed] Termination requires that the progress of the DNA...
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cellular and nuclear pleomorphism is one of the earliest hallmarks of cancer progression and a feature characteristic of malignant neoplasms and dysplasia....
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