Tigecycline, sold under the brand name Tygacil, is a tetracycline antibiotic medication for a number of bacterial infections. It is a glycylcycline class...
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acid Mupirocin (topical) Omadacycline Oritavancin Tedizolid Telavancin Tigecycline (also covers gram negatives) Antibiotics that cover Pseudomonas aeruginosa:...
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resistance, because tigecycline has a higher binding affinity with ribosomal sites than tetracycline has.[citation needed] Tigecycline is capable of killing...
69 KB (8,479 words) - 19:42, 20 October 2024
mediated by acquired efflux pumps and/or ribosomal protection. In 2005, tigecycline, the first member of a new subgroup of tetracyclines named glycylcyclines...
44 KB (4,647 words) - 15:16, 16 January 2025
mediated by acquired efflux pumps and/or ribosomal protection. Presently, tigecycline is the only glycylcycline approved for antibiotic use. The development...
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moxifloxacin because this is the only fluoroquinolone that covers anaerobes. Tigecycline is a tetracycline that can be used due to its coverage of Gram-positives...
22 KB (2,105 words) - 21:54, 13 April 2025
Nitrofurantoin Novobiocin Oxazolidinone Spectinomycin Sulfonamides Tetracyclines Tigecycline Trimethoprim List of antibiotics Oligodynamic effect Pankey GA, Sabath...
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various pharmaceutical uses, such as: tetracycline antibiotics Doxycycline Tigecycline Omadacycline Eravacycline tetracyclic antidepressants Benzoctamine Loxapine...
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microbes to become entirely tolerant of alcohol. Linezolid, daptomycin, tigecycline and the streptogramins (e.g. quinupristin/dalfopristin) can have activity...
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class antibiotic by Tetraphase Pharmaceuticals. It is closely related to tigecycline. It has a broad spectrum of activity including many multi-drug resistant...
16 KB (1,483 words) - 06:47, 29 June 2024
common first-line antibiotics, carbapenems, polymyxins, and more recently tigecycline were considered to be the drugs of choice; however, resistance to these...
92 KB (10,065 words) - 23:49, 23 March 2025
in combination with other active agents (e.g., fosfomycin, colistin, tigecycline). Most common side effects include nausea, vomiting, acid reflux (heartburn)...
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E. faecalis, which is implicated in the vast majority of VRE cases. Tigecycline has also been shown to have antienterococcal activity, as has rifampicin...
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for the treatment of Renal Cell Carcinoma (a type of cancer). Tygacil (tigecycline): an antibiotic developed for treatment of intra-abdominal and skin /...
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to treat. Such bacteria are usually sensitive only to polymyxins and tigecycline. NDM-1 was first detected in 2008 in a culture plate of Klebsiella pneumoniae...
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increasing. It is usually susceptible to piperacillin and ceftazidime. Tigecycline is also an effective drug. Polymyxin B may be effective treatment, at...
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by binding to the bacterial 30S ribosomal subunit. Tetracyclines and Tigecycline (a glycylcycline related to tetracyclines) block the A site on the ribosome...
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Lin HJ, Liu HC, Wu YH, Tsai PJ, et al. (June 2015). "Doxycycline and Tigecycline: Two Friendly Drugs with a Low Association with Clostridium Difficile...
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different mechanisms of action, like vancomycin, linezolid, daptomycin, and tigecycline. Ampicillin can be administered by mouth, an intramuscular injection...
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Linezolid, quinupristin/dalfopristin, daptomycin, ceftaroline, and tigecycline are used to treat more severe infections that do not respond to glycopeptides...
107 KB (12,239 words) - 00:44, 29 March 2025
oxazolidinone 2001 – telithromycin, the first ketolide 2003 – daptomycin 2005 – tigecycline, the first glycylcycline 2005 – doripenem 2009 – telavancin, the first...
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2010s: cyclic lipopeptides (such as daptomycin), glycylcyclines (such as tigecycline), oxazolidinones (such as linezolid), and lipiarmycins (such as fidaxomicin)...
156 KB (14,676 words) - 18:56, 8 April 2025
cost and risk of vision loss or myopathy (due to mitochondrial damage). Tigecycline — used to kill Acinetobacter and Legionella species; this drug is limited...
16 KB (1,856 words) - 11:26, 27 July 2024
Concentrations of Manganese in Mueller-Hinton Agar Increase MICs of Tigecycline Determined by Etest". Journal of Clinical Microbiology. 47 (3): 827–9...
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of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline". Clinical Microbiology and Infection. 14 (Suppl 1): 198–202. doi:10...
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suggested that ertapenem with or without vancomycin is more effective than tigecycline for resolving DFIs. It is also generally unclear whether different antibiotics...
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development of novel and effective antibiotic treatments. Colistin and tigecycline are two of the only antibiotics currently used for treatment, and there...
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progressing to severe-complicated disease the addition of intravenous tigecycline merits considerations. Patients with high risk of relapse may also benefit...
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spirochete Borrelia burgdorferi round-body propagules (RBs) by the antibiotic Tigecycline". Proceedings of the National Academy of Sciences. 106 (44): 18656–18661...
56 KB (5,751 words) - 03:24, 15 March 2025
other tetracyclic antibiotics such as tetracycline, doxycycline, and tigecycline. The drug is used in form of minocycline hydrochloride dihydrate, which...
69 KB (7,022 words) - 04:48, 1 April 2025