Tigecycline, sold under the brand name Tygacil, is a tetracycline antibiotic medication for a number of bacterial infections. It is a glycylcycline class...
32 KB (3,288 words) - 18:27, 20 October 2024
mediated by acquired efflux pumps and/or ribosomal protection. In 2005, tigecycline, the first member of a new subgroup of tetracyclines named glycylcyclines...
44 KB (4,647 words) - 08:45, 6 May 2024
resistance, because tigecycline has a higher binding affinity with ribosomal sites than tetracycline has.[citation needed] Tigecycline is capable of killing...
69 KB (8,479 words) - 19:42, 20 October 2024
acid Mupirocin (topical) Omadacycline Oritavancin Tedizolid Telavancin Tigecycline (also covers gram negatives) Antibiotics that cover Pseudomonas aeruginosa:...
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mediated by acquired efflux pumps and/or ribosomal protection. Presently, tigecycline is the only glycylcycline approved for antibiotic use. The development...
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moxifloxacin because this is the only fluoroquinolone that covers anaerobes. Tigecycline is a tetracycline that can be used due to its coverage of Gram-positives...
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Nitrofurantoin Novobiocin Oxazolidinone Spectinomycin Sulfonamides Tetracyclines Tigecycline Trimethoprim List of antibiotics Oligodynamic effect Pankey GA, Sabath...
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various pharmaceutical uses, such as: tetracycline antibiotics Doxycycline Tigecycline Omadacycline Eravacycline tetracyclic antidepressants Benzoctamine Loxapine...
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microbes to become entirely tolerant of alcohol. Linezolid, daptomycin, tigecycline and the streptogramins (e.g. quinupristin/dalfopristin) can have activity...
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increasing. It is usually susceptible to piperacillin and ceftazidime. Tigecycline is also an effective drug. Polymyxin B may be effective treatment, at...
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to treat. Such bacteria are usually sensitive only to polymyxins and tigecycline. NDM-1 was first detected in 2008 in a culture plate of Klebsiella pneumoniae...
29 KB (3,212 words) - 11:58, 2 November 2024
suggested that ertapenem with or without vancomycin is more effective than tigecycline for resolving DFIs. It is also generally unclear whether different antibiotics...
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oxazolidinone 2001 – telithromycin, the first ketolide 2003 – daptomycin 2005 – tigecycline, the first glycylcycline 2005 – doripenem 2009 – telavancin, the first...
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different mechanisms of action, like vancomycin, linezolid, daptomycin, and tigecycline. Ampicillin can be administered by mouth, an intramuscular injection...
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semisynthesis of antibiotics such as tetracycline, doxycycline, and tigecycline. Other notable examples include the early commercial production of the...
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E. faecalis, which is implicated in the vast majority of VRE cases. Tigecycline has also been shown to have antienterococcal activity, as has rifampicin...
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in combination with other active agents (e.g. fosfomycin, colistin, tigecycline). Most common side effects include nausea, vomiting, acid reflux (heartburn)...
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by binding to the bacterial 30S ribosomal subunit. Tetracyclines and Tigecycline (a glycylcycline related to tetracyclines) block the A site on the ribosome...
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Concentrations of Manganese in Mueller-Hinton Agar Increase MICs of Tigecycline Determined by Etest". Journal of Clinical Microbiology. 47 (3): 827–9...
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Linezolid, quinupristin/dalfopristin, daptomycin, ceftaroline, and tigecycline are used to treat more severe infections that do not respond to glycopeptides...
107 KB (12,252 words) - 17:06, 3 November 2024
common first-line antibiotics, carbapenems, polymyxins, and more recently tigecycline were considered to be the drugs of choice; however, resistance to these...
92 KB (10,005 words) - 19:22, 7 November 2024
cost and risk of vision loss or myopathy (due to mitochondrial damage). Tigecycline — used to kill Acinetobacter and Legionella species; this drug is limited...
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development of novel and effective antibiotic treatments. Colistin and tigecycline are two of the only antibiotics currently used for treatment, and there...
21 KB (2,471 words) - 22:41, 19 September 2024
2010s: cyclic lipopeptides (such as daptomycin), glycylcyclines (such as tigecycline), oxazolidinones (such as linezolid), and lipiarmycins (such as fidaxomicin)...
157 KB (14,742 words) - 20:57, 5 November 2024
for the treatment of Renal Cell Carcinoma (a type of cancer). Tygacil (tigecycline): an antibiotic developed for treatment of intra-abdominal and skin /...
36 KB (3,957 words) - 06:55, 29 October 2024
Rolitetracycline J01AA10 Penimepicycline J01AA11 Clomocycline J01AA12 Tigecycline J01AA13 Eravacycline J01AA14 Sarecycline J01AA15 Omadacycline J01AA20...
14 KB (1,151 words) - 15:36, 25 January 2024
has been found to be more effective and have fewer side effects than tigecycline, but in severe cases it is less effective than piperacillin/tazobactam...
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of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline". Clinical Microbiology and Infection. 14 (Suppl 1): 198–202. doi:10...
44 KB (4,196 words) - 03:02, 12 November 2024
nitrofurantoin (in the case of uncomplicated UTIs), linezolid, quinupristin, tigecycline and daptomycin, although ampicillin is preferred if the bacteria are...
27 KB (3,039 words) - 21:41, 11 November 2024
progressing to severe-complicated disease the addition of intravenous tigecycline merits considerations. Patients with high risk of relapse may also benefit...
54 KB (5,771 words) - 07:21, 12 November 2024