Collagen IV (ColIV or Col4) is a type of collagen found primarily in the basal lamina. The collagen IV C4 domain at the C-terminus is not removed in post-translational...
21 KB (2,423 words) - 04:24, 10 August 2024
Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene. Type IV collagen, the major structural component of basement membranes...
8 KB (1,058 words) - 01:29, 27 March 2024
is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of the type IV collagen and plays a role in angiogenesis. Mutations in the...
19 KB (2,484 words) - 16:19, 1 July 2024
Collagen alpha-4(IV) chain is a protein that in humans is encoded by the COL4A4 gene. This gene encodes one of the six subunits of type IV collagen, the...
7 KB (946 words) - 21:12, 21 November 2023
Collagen alpha-5(IV) chain is a protein that in humans is encoded by the COL4A5 gene. This gene encodes one of the six subunits of type IV collagen, the...
9 KB (1,020 words) - 09:17, 31 July 2023
Alport syndrome (redirect from Alport syndrome, dominant type)
defect in type IV collagen—a structural material that is needed for the normal function of different parts of the body. Since type IV collagen is found...
23 KB (2,440 words) - 19:52, 23 August 2024
Collagen alpha-6(IV) chain is a protein that in humans is encoded by the COL4A6 gene. This gene encodes one of the six subunits of type IV collagen, the...
8 KB (1,033 words) - 09:17, 31 July 2023
III collagen. Formally, the monomers are called collagen type III, alpha-1 chain and in humans are encoded by the COL3A1 gene. Type III collagen is one...
29 KB (3,480 words) - 10:06, 29 July 2024
type IV collagen C4 domain (or collagen IV NC1 domain) is a duplicated domain present at the C-terminus of type IV collagens. Each type IV collagen contains...
3 KB (381 words) - 04:10, 11 December 2023
Collagenase IV may refer to one of two enzymes: Gelatinase A Gelatinase B This disambiguation page lists articles associated with the title Collagenase IV. If...
102 bytes (45 words) - 03:16, 28 December 2019
Collagen alpha-2(IV) chain is a protein that in humans is encoded by the COL4A2 gene. This gene encodes one of the six subunits of type IV collagen, the...
8 KB (1,006 words) - 01:29, 27 March 2024
Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is a protein that in humans is encoded by the COL1A1 gene. COL1A1 encodes the major component...
13 KB (1,792 words) - 00:59, 11 August 2024
and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture's antigen. Goodpasture...
14 KB (1,428 words) - 23:54, 3 March 2024
Associated Collagens with Interrupted Triple Helices) (Type IX, XII, XIV, XIX, XXI) Short chain (Type VIII, X) Basement membrane (Type IV) Multiplexin...
70 KB (7,693 words) - 15:43, 20 July 2024
Collagen VI (ColVI) is a type of collagen primarily associated with the extracellular matrix of skeletal muscle. ColVI maintains regularity in muscle...
19 KB (2,434 words) - 18:37, 24 September 2023
Type IV hypersensitivity, in the Gell and Coombs classification of allergic reactions, often called delayed-type hypersensitivity, is a type of hypersensitivity...
7 KB (508 words) - 10:59, 15 March 2024
gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the...
20 KB (2,218 words) - 16:07, 5 April 2024
cells of the epidermis, and composed of 1) type IV collagen, 2) anchoring fibrils made of type VII collagen, and 3) dermal microfibrils. Basal lamina James...
790 bytes (88 words) - 04:54, 2 June 2024
Osteogenesis imperfecta (redirect from OI type IV)
problem with connective tissue due to a lack of, or poorly formed, type I collagen.: 1513 In more than 90% of cases, OI occurs due to mutations in the...
150 KB (15,367 words) - 14:58, 14 July 2024
defect in the structure of the type-IV collagen fibrils of the glomerular basement membrane. As a consequence, the collagen fibrils of the glomerular basement...
24 KB (2,711 words) - 22:48, 12 August 2024
damage to the basement membrane by antibodies to alpha 3 NC1 domain of type IV collagen. Nephrotic syndrome is a change in the structure of the glomerular...
5 KB (382 words) - 16:52, 2 August 2024
Rapidly progressive glomerulonephritis (section Type I)
is characterized by the presence of autoantibodies directed against type IV collagen (specifically, the noncollagenous region of its α3 chain) in the glomerular...
11 KB (1,029 words) - 22:44, 26 August 2024
The collagenases digest types I, II, III, VII and X collagen. The gelatinases exist in two forms; one digesting Type-IV collagen and one digesting gelatin...
51 KB (5,914 words) - 21:10, 16 August 2024
algorithm Type IV collagen, a class of collagen Type-4 hypersensitivity, a class of Hypersensitivity reactions that involves T-cells IEC Type IV, one of...
1 KB (194 words) - 01:26, 17 September 2023
podocyte processes. The lamina densa is the central layer consisting of type IV collagen and laminin. This layer acts as a selective macromolecular filter,...
5 KB (579 words) - 05:55, 22 August 2024
suggesting genetic predisposition within the family, that encodes type IV collagen α1 chain has shown to be associated with and present in patients with...
18 KB (2,157 words) - 19:20, 2 July 2024
Lymphangitis (inflammation of lymphatic vessels) is sometimes considered a type of vasculitis. Vasculitis is primarily caused by leukocyte migration and...
19 KB (1,585 words) - 12:48, 8 August 2024
membrane disease has yet to be elucidated fully; however, defects in type IV collagen have been reported in some families. Some individuals with TBMD are...
7 KB (762 words) - 21:22, 31 December 2023
Sponge (section Cell types)
fibers that reinforce the mesohyl of all demosponges is similar to "type IV" collagen. The analyses described above concluded that sponges are closest to...
129 KB (13,202 words) - 07:56, 25 August 2024
preferentially binds collagens IV, VI and type XIII collagen, but also fibril-forming collagens. Specific binding sites in collagen I and IV have been identified...
8 KB (1,090 words) - 21:55, 30 September 2023